Evaluation of Antioxidant and Antiproliferation Activities of 10 Kinds of Guangdong Medicinal and Edible Plant

Hongxia WAN; Yumei HU; Qiang JIA; Huan OUYANG; Peifang XUE

doi:10.13386/j.issn1002-0306.2020050135

Volume 42 Issue 8

Apr. 2021

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Science and Technology of Food Industry > 2021 > 42(8): 307-312. > DOI: 10.13386/j.issn1002-0306.2020050135

WAN Hongxia, HU Yumei, JIA Qiang, et al. Evaluation of Antioxidant and Antiproliferation Activities of 10 Kinds of Guangdong Medicinal and Edible Plant[J]. Science and Technology of Food Industry, 2021, 42(8): 307−312. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2020050135.

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Evaluation of Antioxidant and Antiproliferation Activities of 10 Kinds of Guangdong Medicinal and Edible Plant

1.
Food department, Guangzhou City Polytechnic, Guangzhou 510405, China
2.
Ying-dong College of Food Science and Engineering, Shaoguan University, Shaoguan 512005, China

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Received Date: May 12, 2020
Available Online: January 27, 2021

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Abstract

Abstract

The flavonoids content (AlCl₃-NaNO₂ method) and total polyphenol contents (Folin-Ciocalteu method) of 10 kinds of Guangdong medicinal and edible plant extracts were determinated. The antioxidant activity (DPPH radical scavenging activity and hydroxyl radical scavenging activity) and the antiproliferation activity of mice colorectal cancer MC-38 cell (CCK-8 kit method) were evaluated. The correlation between the activity of active substance and its contents were analyzed. The results showed that the highest content of total flavonoids was galangal (85.76 ± 3.25 μmol CE/g DW) of 10 Guangdong medicinal and edible plants, and the lowest content of total flavonoids were Kaempferia (0.80 ± 0.05 μmol CE/g DW) and longan (0.69 ± 0.03 μmol CE/g DW). The highest content of total polyphenol (226.26 ± 9.17 μmol GAE/g DW), and the lowest content of total polyphenol was Kaempferia (7.52 ± 0.67 μmol GAE/g DW). The DPPH free radical scavenging activity of the strongest for galangal, the weakest activity for Kaempferia. The activity of scavenging hydroxyl free radical was strongest in Kaempferia, Alpinia oxyphylla and nutmeg(there was no significant difference among them), and the activity was weakest in orange peel. The anti-MC-38 cell proliferation activity was strongest in orange peel and galangal, and weakest in longan. DPPH radical scavenging activity was significantly correlated with the content of total flavonoids and total polyphenols (P<0.05). The correlation between Anti-MC-38 cell proliferation activity and the content of total flavonoids and total polyphenol was very significant (P<0.01). There was no significant correlation between the scavenging activity of hydroxyl radical and the content of total flavonoids and total polyphenols. Although the active efficacy of water extract of edible and medicinal plants had dose effect, it was also affected by the kinds and synergistic effects of its components.
- medicinal and edible plant,
- DPPH radical,
- hydroxyl radical,
- antioxidant activity,
- antiproliferative activity

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