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中国精品科技期刊2020
司洲,陈昊翔,樊梓鸾. 五味子多糖提取、结构特征及生物活性研究进展[J]. 食品工业科技,2024,45(3):1−9. doi: 10.13386/j.issn1002-0306.2023060200.
引用本文: 司洲,陈昊翔,樊梓鸾. 五味子多糖提取、结构特征及生物活性研究进展[J]. 食品工业科技,2024,45(3):1−9. doi: 10.13386/j.issn1002-0306.2023060200.
SI Zhou, CHEN Haoxiang, FAN Ziluan. Progress on the Extraction, Structure Characterization and Bioactivity of Schisandra chinensis Polysaccharides[J]. Science and Technology of Food Industry, 2024, 45(3): 1−9. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2023060200.
Citation: SI Zhou, CHEN Haoxiang, FAN Ziluan. Progress on the Extraction, Structure Characterization and Bioactivity of Schisandra chinensis Polysaccharides[J]. Science and Technology of Food Industry, 2024, 45(3): 1−9. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2023060200.

五味子多糖提取、结构特征及生物活性研究进展

Progress on the Extraction, Structure Characterization and Bioactivity of Schisandra chinensis Polysaccharides

  • 摘要: 五味子是木兰科植物五味子(Schisandra chinensis (Turcz.) Baill),或华中五味子(Schisandra sphenanchera Rehd. etWils.)的干燥成熟果实,富含多糖、木脂素、挥发油、多酚等多种活性成分。多糖作为其主要的活性成分,提取工艺有双水相萃取、酶解法、超声法、微波法、超声微波协同、微波酶法协同、水提法等,其中双水相萃取效率最高,超声法和水提法应用最广泛。五味子多糖主要由鼠李糖、甘露糖、葡萄糖、半乳糖、阿拉伯糖和半乳糖醛酸组成,平均分子量大致范围在103~105 Da。现代药理学研究表明,五味子多糖具有显著的抗氧化、免疫调节、抗肿瘤、保肝、降血糖、血脂等功效,在食品、医药领域高值化开发具有重要的意义。因此,本文对近年来国内外五味子多糖提取工艺、结构特征和生物活性及其相关机制进行系统总结,并对其研究方向与应用前景进行展望,以期为五味子深入研究和应用开发提供参考。

     

    Abstract: Schisandra chinensis refers to the dried mature fruit of the plant Schisandra chinensis (Turcz.) Baill from the Magnoliaceae family, or Schisandra sphenanchera Rehd. etWils. It is rich in various active components such as polysaccharides, lignans, volatile oils, and polyphenols. Polysaccharides, as its main active ingredients, are extracted by biphasic extraction, enzymatic method, ultrasonic method, microwave method, ultrasonic-microwave synergy, microwave-enzymatic synergy, and aqueous extraction, among which biphasic extraction has the highest efficiency, and ultrasonic and aqueous extraction are the most widely used methods. Schisandra chinensis polysaccharides are mainly composed of rhamnose, mannose, glucose, galactose, arabinose and galacturonic acid, and the average molecular weight roughly ranges from 103~105 Da. Modern pharmacological studies have shown that Schisandra chinensis polysaccharides have significant antioxidant, immunomodulatory, antitumor, hepatoprotective, hypoglycemic and lipid-lowering efficacy, and they are of significant significance for the development of high-value in the field of food and medicine. Therefore, this paper systematically summarizes the extraction process, structural characteristics and biological activities of Schisandra chinensis polysaccharides and their related mechanisms at home and abroad in recent years, and looks forward to its research direction and application prospects, with a view to providing reference for the in-depth research and application development of Schisandra chinensis.

     

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