Abstract: Based on the core corpus of Web of Science (WOS), CiteSpace software is utilized to analyze the annual number of publications, authors, institutional and national cooperation networks, keyword co-occurrence and emergence, and literature co-citation maps of 8310 related articles and reviews which is in the field of food and gut microbiota and published between 2004 and 2022. The results present that the annual number of publications in the field of food and gut microbiota is increasing from 2005, and the main research topic in this field is the influence of diet on gut microbiota and related diseases. Currently, research frontier is emulsifiers, symbiosis, gut microbiota, Akkermansia muciniphila, and Kefir. The number of publications from Chinese authors rank second in this field, but the international cooperation is lacking. In the future, more international cooperation should be performed to improve research skills.