Abstract: Dynamic high pressure microfluidization (DHPM) is a newly developed food processing technology, it has important applications in the preparation process of emulsification, homogenization and refinement of delivery systems due to its strong shearing, crushing, high-velocity impact, cavitation, oscillation and expansion. Herein, technologies of emulsification and homogenization, technical characteristics of emulsion preparation using DHPM, and the applications of DHPM in the preparation of emulsion-based delivery systems are summarized, to provide theoretical reference for promoting the progress of DHPM and the industrial production of emulsion-based delivery systems.