Abstract: The triterpenes are the typical bioactive components in the Ganoderma lucidum, which has high valuable application and development in the field of medicine and health food. In this paper, by consulting literature and summarizing data, the main techniques and methods of extraction, separation and purification of Ganoderma lucidum triterpenes and their biological activities are reviewed, and the problems existing in the research and application development of Ganoderma lucidum triterpenes are analyzed. Moreover, the future research and application development of the biological activities are prospected in order to provide corresponding reference for the research, application and development of the Ganoderma lucidum triterpenes.