Abstract: Traditional Chinese medicine fermentation technology is an important method with a long history. With the improvement of national health awareness, the usage of probiotics in fermented traditional Chinese medicine has become a hot spot in scientific research. At the same time, probiotics have been widely used in dual-use traditional Chinese medicine. A series of healthy products developed by traditional Chinese medicine fermentation technology are favored by consumers and have broad market prospects. Traditional Chinese medicine fermented by probiotics has the advantages of improving efficacy, easier absorption by the human body, and reducing toxic and side effects. This article described the research status of traditional Chinese medicine fermented by probiotics from two aspects:Single strain fermentation and multi strain mixed fermentation. And probiotic fermented edible traditional Chinese medicine development of related products were reviewed. It provided a reference for further research and development in this field.