Abstract: Enzymes are biocatalysts that can perform complex chemical reactions, and have excellent properties such as high activity, good selectivity, and environmental friendliness. However, the sources of enzymes used for catalytic reactions are relatively narrow, the space structure is relatively flexible and easily inactivated. The poor catalytic stability is inadequate, which has objectively limited its further expansion. Enzyme catalytic performance enhancement, including increasing enzyme activity and increasing enzyme catalytic stability, is a research hotspot in the field of bioengineering in recent years. Different carbohydrates have different degrees of protection on enzyme activity. Dextran is a kind of homologous polysaccharide with glucose as unit and connected by glycoside bond. More and more attentions have been paid to the enhancement of enzyme catalytic performance. In recent years, there are relatively many research reports on the enhancement of dextran in the catalytic performance of enzymes. This article mainly reviewes the research progress of dextran as a crosslinking agent, modifier and additive in the process of enzyme immobilization. Examples of the application of sugar in organic solvent and solvent-free enzyme catalytic systems, the effect of dextran on the catalytic performance of the enzyme were analyzed, which laid the foundation for the further application of dextran in enzyme catalysis.