Abstract: A ion chromatography method( IC) was developed for the determination of 14 organic acid and anion in noni powder by Dionex ICS-5000 with conductivity detection.The separation of the organic acids and inorganic anions in noni powder was performed on Ion Pac AS11- HC analytical column plus Ion Pac AG11- HC guard column,ASRS 300( 4 mm) electric inhibition model,and KOH as gradient eluent at a flow rate of 1.0 m L / min. The column temperature was 30 ℃. At the above chromatographic conditions,ideal separation of 14 organic acid and anion can be obtained.The analysis mothod exhibited a good linear relationship( r≥0.9988) at the range of 1 ~ 50 mg / L,low detection limit( ≤0.508 mg / L),good recovery( 91.50% ~107.22%),and good precision( RSD% ranging from 0.18% to 5.2%,n = 8).The organic acids and inorganic anions component within Noni powder were lactic acid,malic acid,oxalic acid,citric acid,chloride,sulfate and phosphate.The concentration of those analytes that mentioned above were 5.893,74.631,9.631,10.826,27.930,4.226,7.747 mg / g respectively while some of which were not detected.This developed method was simple,efficient,and suitable for the determination of these14 organic acid and anion in noni powders.