Abstract: The antioxidative activity of sesame coat extraction were increased after being soaked with hydrochloric acid in certain acid concentration,soaking temperature and time. On the basis of single-factor experiments,an orthogonal experiment was carried out.According to the orthogonal experiment,the best acid soaking technological condition was obtained.When using0.35 mol/L of hydrochloric acid,soaking procedure conducted for 1.5 h with temperature of 70 ℃,and material-liquid ratio of1∶10,the free radical scavenging capacities of extraction to 2,2-diphenyl-1-picrylhydrazyl radical( DPPH·) was 86.35%.However,at the same concentration of extraction from no acid soaking sesame coat,the free radical scavenging capacities of extraction to 2,2-diphenyl-1-picrylhydrazyl radical( DPPH·) was just 32.27%. The conclusion is that acid soaking sesame coat can increase the antioxidation of lignans.