Abstract: Cabernet Sauvignon grape leaves collected from Bazhou area in southern Xinjiang were used as the subjects to extract resveratrol through microwave assistant method,and NKA- Ⅱ resin for purification.Experiments showed that the optimum technological conditions for extraction of resveratrol from grape leaves assisted by microwave method were ethanol concentration 40%,microwave power 640 W,extraction time 76 s,ratio of solid to liquid 1∶92. Under these conditions,the extraction of resveratrol was 13.52 mg/g. Through the static test screening,resveratrol the crude product was purified using NKA-II resin. The optimum technological conditions were as follows:the sample solution volume was 6 BV,the concentration of resveratrol 3 mg/m L,the p H of absorbing stock solution was 4,the dynamically absorbing rate of flow was 2 BV/h,with four times the column volume of,90% ethanol solution as desorption agent under flow rate 3 BV/h. And the purity increased from 35.7352 mg/g to 181.5888 mg/g. Conclusion:Although the extraction rate of microwave assisted method was not the highest,but the time was short,and was suitable for industrial production,purification although had certain effect,but still need further research.