Abstract: The dry fruiting body power of Dictyophora indusiata was extracted by ethylether and ethyl acetate after n-hexane extraction. The ethylether and ethyl acetate extraction rate was 1.57% and 1.85%, respectively.The chemical composition of the extracts had been identified by GC-MS. The analysis results showed that forty-three components had been identified from ethylether extracts and their content was of 99.98%. Seventythree components had been identified from ethyl acetate extracts and their content was of 99.56%. Two kinds of extraction showed a significant antimicrobial activity to Staphylococcus aureus, Bacterium vulgare, Bacillus subtilis and Salmonella typhosa. The inhibitory effect of ethyl acetate extracts were better than that of ethylether extracts.