Abstract: Tea-polyphenol was encapsulated by sodium alginate and chitosan, and prepared by spray drying technology. The optimum conditions of microencapsulating were listed as follows:spray drying condition optimization included inlet air temperature of 180℃ , air flow 750L/h, outlet air temperature of 100℃ ;the wall material optimization included that the mass ratio of the core and wall material was 2 ∶1. The mass ratio of the wall materials were showed as follow:sodium alginate 2.5% (v/v) , chitosan 0.8% (v/v) , calcium chloride 4.5% (v/v) . The best embedding rate was 73.8%, meanwhile the global microencapsulation diameter were nearly about 2¹0μm. The favorite preservative condition was at 5℃ for 22d.