Abstract: In this experiment, optimization for anthocyanins extraction from purple leaves of Camellia ptilophylla chang was investigated using response surface methodology.The optimization strategy used was a three-factor three-level quadratic regression rotary combination design.The importance of three process parameters affecting extraction yield of anthocyanins in the order from highest to lowest was:ultrasonic treatment time, ultrasonic power, liquid-to-solid ratio.Ultrasonic treatment time of 25min, ultrasonic power 158W, liquid-to-solid ratio 1∶33 (g/mL) were found optimum for anthocyanins extraction from Camellia ptilophylla chang.Under the optimum technology, the extraction of anthocyanins was 8.092mg/g.