Application of Ion Mobility Mass Spectrometry in Food Analysis

SI Bo; GU Yating; YANG Chen; LU Yongling; LÜ Lishuang

doi:10.13386/j.issn1002-0306.2023100003

Volume 45 Issue 19

Sep. 2024

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Science and Technology of Food Industry > 2024 > 45(19): 399-406. > DOI: 10.13386/j.issn1002-0306.2023100003

SI Bo, GU Yating, YANG Chen, et al. Application of Ion Mobility Mass Spectrometry in Food Analysis[J]. Science and Technology of Food Industry, 2024, 45(19): 399−406. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2023100003.

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Application of Ion Mobility Mass Spectrometry in Food Analysis

1.
Suqian Product Quality Supervision and Inspection Institute, Suqian 223800, China
2.
College of Food and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, China

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Received Date: October 08, 2023
Available Online: July 29, 2024

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Abstract

Abstract

Ion mobility spectroscopy is a technique to characterize compounds based on the differences in the migration of sample ions under the combined action of electric field and air flow. Ions can be separated according to their quantity of electric charge, mass, size and shape. Meanwhile, the collision cross section of the ions can also be calculated to obtain chemical compound structural information, which has shown excellent performance in separating isomers of substances. In recent years, a variety of ion mobility technologies combined with mass spectrometry technology have emerged, and been widely used in food, biology, medicine, environment and other fields. In this paper, the types and working principles of ion mobility spectroscopy are introduced, the advantages and disadvantages of various types of instruments are analyzed, and the application of ion mobility spectrometry, liquid chromatography and mass spectrometry multidimensional combination in analyzing and identifying nutritive and active ingredients and chemical hazards in food is reviewed. The application prospect and development trend of this technology are also prospected.

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