Research Status of Peptide-Calcium Chelation and Absorption Mechanism

ZHANG Haotong; ZHOU Xuewei; QIAO Kaina; WU Huimin; YANG Rui; ZHANG Yuyu

doi:10.13386/j.issn1002-0306.2023080325

Volume 45 Issue 19

Sep. 2024

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Science and Technology of Food Industry > 2024 > 45(19): 383-391. > DOI: 10.13386/j.issn1002-0306.2023080325

ZHANG Haotong, ZHOU Xuewei, QIAO Kaina, et al. Research Status of Peptide-Calcium Chelation and Absorption Mechanism[J]. Science and Technology of Food Industry, 2024, 45(19): 383−391. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2023080325.

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Research Status of Peptide-Calcium Chelation and Absorption Mechanism

ZHANG Haotong^{1, 2, 3,},
ZHOU Xuewei^{2, 3},
QIAO Kaina^{2, 3},
WU Huimin^{1, 2, 3},
YANG Rui¹,
ZHANG Yuyu^{2, 3, ,}

1.
College of Food Science and Engineering, Tianjin University of Science & Technology, Tianjin 300457, China
2.
Food Laboratory of Zhongyuan, Beijing Technology and Business University, Beijing 100048, China
3.
Key Laboratory of Flavor Science of China General Chamber of Commerce, Beijing Technology and Business University, Beijing 100048, China

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Received Date: September 03, 2023
Available Online: August 01, 2024

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Abstract

Abstract

Calcium is one of the essential macro-elements in the human body. The scientific calcium supplementation is greatly significant to maintaining life and health. The peptide-calcium chelates with good calcium binding capacity and high bioavailability have attracted more attention. This work reviews the binding sites, binding modes, and intermolecular forces between calcium and peptides in peptide-calcium chelates. Compared with free calcium, chelated calcium is more easily absorbed in the intestine according to the summarization of the calcium absorption pathways. Peptide-calcium chelates, as a new generation of calcium supplements, have a rich source of raw materials, high bioavailability, good economic value, and broad development prospects. Further research is needed on the safety, physicochemical stability, digestive stability, and Ca²⁺ release mechanism of peptide-calcium chelates after intestinal absorption. This paper aims to provide new insight into the development of novel calcium supplements.
- calcium,
- peptide-calcium chelates,
- calcium supplements,
- calcium absorption

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References

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