Research Progress on Oral Nano-formulation to Deliver Astaxanthin

ZHONG Chen; LIU Mei; GAO Yan; XU Kefeng; WANG Ying

doi:10.13386/j.issn1002-0306.2023070028

Volume 45 Issue 10

May 2024

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Science and Technology of Food Industry > 2024 > 45(10): 395-400. > DOI: 10.13386/j.issn1002-0306.2023070028

ZHONG Chen, LIU Mei, GAO Yan, et al. Research Progress on Oral Nano-formulation to Deliver Astaxanthin[J]. Science and Technology of Food Industry, 2024, 45(10): 395−400. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2023070028.

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Research Progress on Oral Nano-formulation to Deliver Astaxanthin

ZHONG Chen^1,,
LIU Mei¹,
GAO Yan¹,
XU Kefeng¹,
WANG Ying^{1, 2, ,}

1.
Marine Science Research Institute of Shandong Province, Qingdao 266104, China
2.
Municipal Engineering Research Center of Aquatic Biological Quality Evaluation and Application,Qingdao 266104, China

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Received Date: July 04, 2023
Available Online: March 19, 2024

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Abstract

Abstract

Astaxanthin is a fat-soluble lutein carotenoid with good antioxidant, anti-inflammatory and immunomodulatory activities. However, its poor oral bioavailability lead to limited clinical application. Recently, in order to improve the bioavailability of astaxanthin, various types of nano-formulations have been widely studied. Nano-emulsion, liposome, solid lipid nanoparticles, chitosan and PLGA nanoparticles have been shown to effectively improve the oral bioavailability of astaxanthin. In this review, based on in vitro and in vivo studies, the research progress of nano-formulations for improving the oral bioavailability of astaxanthin are summarized, providing reference for the development of oral delivery of astaxanthin, and achieving its clinical application value in the future.
- astaxanthin,
- oral formulation,
- nanoparticles,
- bioavailability

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References

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