Research Progress on Antitumor Mechanism of 6-Shogaol

WANG Zhuan; HU Hongliu; CHEN Qifeng; ZHOU Jie; REN Zhenzhen; JIANG Lihe

doi:10.13386/j.issn1002-0306.2022080339

Volume 44 Issue 11

May 2023

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Science and Technology of Food Industry > 2023 > 44(11): 480-486. > DOI: 10.13386/j.issn1002-0306.2022080339

WANG Zhuan, HU Hongliu, CHEN Qifeng, et al. Research Progress on Antitumor Mechanism of 6-Shogaol[J]. Science and Technology of Food Industry, 2023, 44(11): 480−486. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2022080339.

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Research Progress on Antitumor Mechanism of 6-Shogaol

WANG Zhuan^{1, 2,},
HU Hongliu³,
CHEN Qifeng²,
ZHOU Jie²,
REN Zhenzhen³,
JIANG Lihe^{1, 2, 3, ,}

1.
College of Light Industry and Food Engineering, Guangxi University, Nanning 530004, China
2.
Medical College, Guangxi University, Nanning 530004, China
3.
School of Basic Medical Sciences, Youjiang Medical University for Nationalities, Baise 533000, China

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Received Date: August 30, 2022
Available Online: April 02, 2023

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Abstract

Abstract

The incidence and mortality of cancer are increasing year by year, which seriously threatens human health. 6-Shogaol, as one of the main active components in ginger, has become the focus of attention in recent years due to its advantages of safety and low toxicity. Moreover, it has anti-inflammatory, antioxidant, anti-tumor and other pharmacological effects. Particularly, its anti-tumor activity has received increasing attention. This paper reviews the anti-tumor mechanism of 6-shogaol, including inhibition of cell proliferation, induction of cell apoptosis, arrest of cell cycle, inhibition of cell migration and invasion, effect of autophagy in tumor cells, etc., in order to provide ideas for further research, development and application of 6-shogaol in anti-tumor.
- 6-shogaol,
- anti-tumor,
- mechanism of action,
- research progress

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References

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