Research Progress of Polyphenols in Reducing Lactoprotein Sensitization

NONG Liyan; TANG Daobang; LIU Xueming; WANG Xuping; CHENG Jingrong; LIN Yaosheng; ZOU Jinhao; YANG Huaigu

doi:10.13386/j.issn1002-0306.2022080301

Volume 44 Issue 12

Jun. 2023

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Science and Technology of Food Industry > 2023 > 44(12): 422-429. > DOI: 10.13386/j.issn1002-0306.2022080301

NONG Liyan, TANG Daobang, LIU Xueming, et al. Research Progress of Polyphenols in Reducing Lactoprotein Sensitization[J]. Science and Technology of Food Industry, 2023, 44(12): 422−429. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2022080301.

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Research Progress of Polyphenols in Reducing Lactoprotein Sensitization

1.
Sericultural & Agri-Food Research Institute, Guangdong Academy of Agricultural Sciences, Key Laboratory of Functional Foods, Ministry of Agriculture and Rural Affairs, Guangdong Key Laboratory of Agricultural Products Processing, Guangzhou 510610, China
2.
College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China

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Received Date: August 30, 2022
Available Online: April 10, 2023

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Abstract

Abstract

Certain infants and children have relatively high risk of the onset of anaphylaxis when exposed to the foods containing cow milk protein. This pathogenic immunological process is mainly mediated by IgE. Currently, the chief methods eliminating the sensitization of milk protein include heat treatment, high pressure treatment, enzymatic hydrolysis, and glycosylation modification, etc. Based on different mechanisms, each technique has specific advantages, nevertheless, also accompanied with ineluctable shortcomings, such as reducing the nutritional value or generating odd flavors. As a type of secondary metabolites with wide botanical resources, polyphenols exhibit pleiotropic bioactivities involving anti-aging, antibiosis, anti-inflammation and antioxidation. It is well known that polyphenols have strong affinity to proteins via covalent or non-covalent binding, which is so-called 'polyphenol-protein interaction (PPI)'. Accumulating reports showed that phenolic compounds could reduce the immunoreactivity of diverse food allergens through PPI. This review summarizes and discusses the role of PPI on the desensitization of lactoproteins, and proposed some promising conceptions in the light of up-to-date researches, hoping to provide new ideas and theoretical foundations for the development of safe dairy products of low-sensitization.
- plant polyphenols,
- cow milk protein,
- polyphenol-protein interaction,
- desensitization

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References (69)

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