Intestinal Flora: A New Target for the Treatment of Parkinson's Disease

YU Jie; LI Qi; ZHAO Feiyan

doi:10.13386/j.issn1002-0306.2022050347

Volume 43 Issue 21

Oct. 2022

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Science and Technology of Food Industry > 2022 > 43(21): 1-8. > DOI: 10.13386/j.issn1002-0306.2022050347

YU Jie, LI Qi, ZHAO Feiyan. Intestinal Flora: A New Target for the Treatment of Parkinson's Disease[J]. Science and Technology of Food Industry, 2022, 43(21): 1−8. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2022050347.

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Intestinal Flora: A New Target for the Treatment of Parkinson's Disease

Inner Mongolia Key Laboratory of Dairy Biotechnology and Engineering, Key Laboratory of Dairy Products Processing, Ministry of Agriculture and Rural Affairs, Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, Inner Mongolia Agricultural University, Hohhot 010018, China

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Received Date: May 29, 2022
Available Online: August 20, 2022

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Abstract

Abstract

Parkinson's disease (PD) is a neurodegenerative disease influenced by genetic and environmental factors, and its pathogenesis is still unclear. Compared with healthy people, the intestinal flora of patients with PD is disturbed, which is manifested by an increase in the abundance of intestinal microbial and an increase in specific bacteria. Probiotics can effectively improve the quality of PD patients' life by regulating the intestinal flora and improving symptoms such as inflammation, constipation and abdominal pain. Based on these properties, probiotics are expected to become an adjunct to the treatment of Parkinson's disease in real life. Starting from the aspects of intestinal flora, disease course and treatment methods of Parkinson's patients, this paper reviews the research reports in recent years. Moreover, this paper summarizes the characteristics of intestinal flora of Parkinson's patients and the relationship between them, and discusses the new therapeutic methods of probiotic intervention, which provides a new reference for the treatment of Parkinson's disease.
- Parkinson's disease,
- intestinal flora,
- flora disorder,
- probiotics

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References

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