Simultaneous Determination of Seventeen Active Ingredients in Novel Tianlongquan Pithos Stored Liquor by HPLC

MO Wei; ZHANG Long; YE Jingxuan; LIANG Zhenrong; WAN Ruijie; ZHANG Yuhong; YANG Jinhai; HAO Junguang

doi:10.13386/j.issn1002-0306.2022050249

Volume 44 Issue 5

Feb. 2023

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Science and Technology of Food Industry > 2023 > 44(5): 299-307. > DOI: 10.13386/j.issn1002-0306.2022050249

MO Wei, ZHANG Long, YE Jingxuan, et al. Simultaneous Determination of Seventeen Active Ingredients in Novel Tianlongquan Pithos Stored Liquor by HPLC[J]. Science and Technology of Food Industry, 2023, 44(5): 299−307. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2022050249.

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Simultaneous Determination of Seventeen Active Ingredients in Novel Tianlongquan Pithos Stored Liquor by HPLC

MO Wei^{1, 2, 3,},
ZHANG Long^{4, 5},
YE Jingxuan⁴,
LIANG Zhenrong⁴,
WAN Ruijie^{4, 5},
ZHANG Yuhong^{2, 3},
YANG Jinhai⁶,
HAO Junguang^{2, 3, ,}

1.
College of Light Industry and Food Engineering, Guangxi University, Nanning 530000, China
2.
Qinzhou Key Laboratory of Food Flavor Analysis and Control, College of Food Science and Engineering, Beibu Gulf University, Qinzhou 535011, China
3.
Guangxi College and University Key Laboratory of High-value Utilization of Seafood and Prepared Food in Beibu Gulf, College of Food Engineering, Beibu Gulf University, Qinzhou 535011, China
4.
Guangxi Tianlongquan Wine Co., Ltd., Luocheng 546400, China
5.
Jin Pai Co., Ltd., Daye 435100, China
6.
Institute of Science and Technology Information of Luocheng Mulao Autonomous County, Luocheng 546400, China

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Received Date: May 22, 2022
Available Online: December 31, 2022

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Abstract

Abstract

Objective: In order to satisfy the enterprise's precise control the dosage of active ingredients in the new Tianlongquan pithos-stored liquor dosed with radix puerariae, siraitiae fructus and tartary buckwheat extracts. To establish a method for the simultaneous determination of 17 active ingredients (3′-hydroxypuerarin, chlorogenic acid, puerarin, epicatechin, catechins, 3′-methoxypuerarin, puerarin apioside, daidzin, ferulic acid, rutin, quercetin, isoquercitrin, kaempferol-3-O-rutinoside, mogroside IV, mogroside V, quercetin, kaempferol) by high performance liquid chromatography (HPLC). Methods: Through gradient optimization was carried out to separate each component effectively, and methodological investigations was performed for quantitation method. Results: The effective separation was achieved within 70 min on a Waters Atlantis^®T3 column (4.6 mm×250 mm, 5 μm) using a optimized gradient of mobile phase consisting of acetonitrile-0.1% phosphoric acid water, and with the quantitative wavelength was 203, 250, 280 and 365 nm correspondingly. This quantitative method was of with good repeatability (relative standard deviation RSD≤4.06%), high precision (RSD≤3.86%) and reliable recovery (average recoveries ranging from 92.46% to 106.25%, RSD≤4.56%). Conclusion: The method is simple, efficient and accurate, and suitable for the quality control of the active ingredients in pithos-stored liquor.
- high performance liquid chromatography (HPLC),
- active ingredients,
- product quality,
- Tianlongquan pithos-stored liquor

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References (27)

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