JIN Gangliang, TANG Hao, XIAN Shaohua, et al. Visualization Analysis of Research Progress and Trends for the Biological Activities of Moringa oleifera Lam. DOI: 10.13386/j.issn1002-0306.2022050195
Citation: JIN Gangliang, TANG Hao, XIAN Shaohua, et al. Visualization Analysis of Research Progress and Trends for the Biological Activities of Moringa oleifera Lam. DOI: 10.13386/j.issn1002-0306.2022050195

Visualization Analysis of Research Progress and Trends for the Biological Activities of Moringa oleifera Lam.

More Information
  • Received Date: May 18, 2022
  • Available Online: December 25, 2022
  • Based on the databases of Web of Science (WOS) core collection and CNKI, we performed the visual analysis to the biological activity study of Moringa oleifera Lam. included in these databases from 2000 to 2021 by means of Citespace software (5.8 R3 vision). Anyway, it is the first time that the retrospective study on the biological activity study of M. oleifera Lam. during the past two decade were investigated through Citespace information-visualization analysis method, it is helpful for its prospective study on research hotspot prediction. In this article, we trailed and analyzed several dimensions which included their annual literature distribution, research institutions, national/regional distribution, and so on. Furthermore, the change trends of their research hotspots in the home and abroad with the time change also were analyzed through the keywords and Citespace co-citation clustering, the visual network characteristics of hot topics and evolution revealed the change trend. Eventually, through the investigation study on the reported literatures, we found that Moringa oleifera Lam. had significant advantages in preventing and treating many metabolic diseases. In this regard, we reviewed its current research progress in detail. To sum up, through bring Citespace information-visualization analysis methods to the biological activity study of M. oleifera Lam.in this paper, it was aimed to enable scientific researchers to have a more comprehensive understanding on the activity study trends of M. oleifera Lam., and attract their attention to potential research hotspots, and further promote high value utilization of M. oleifera Lam..
  • [1]
    景志贤, 李梦, 张小波, 等. 基于全球气候数据和MaxEnt模型的辣木全球气候适宜区研究[J]. 中国现代中药,2021,23(8):1352−1356. [JING Z X, LI M, ZHANG X B, et al. Study on the global climate suitable area of Moringa oleifera based on global climatedata and MaxEnt model[J]. Morden Chinese Medicine,2021,23(8):1352−1356. doi: 10.13313/j.issn.1673-4890.20200403005
    [2]
    高启霞, 沙子珺, 唐仕欢, 等. 辣木化学成分及其药理作用研究进展[J]. 医药导报,2020,39(3):350−359. [GAO Q X, SHA Z J, TANG S H, et al. Study on chemical constituents and pharmacological effects of Moringa oleifera: A review[J]. Herald of Medicine,2020,39(3):350−359.
    [3]
    刘子记, 孙继华, 刘昭华, 等. 特色植物辣木的应用价值及发展前景分析[J]. 热带作物学报,2014,35(9):1871−1878. [LIU Z J, SUN J H, LIU Z H, et al. Application value and development prospect of characteristic plant Moringa oleifera[J]. Chinese Journal of Tropical Crops,2014,35(9):1871−1878. doi: 10.3969/j.issn.1000-2561.2014.09.035
    [4]
    LIU J, MA G M, WANG Y, et al. Moringa oleifera leaf flavonoids protect bovine mammary epithelial cells from hydrogen peroxide-induced oxidative stress in vitro[J]. Reproduction in Domestic Animals,2020,55(6):711−719. doi: 10.1111/rda.13670
    [5]
    BARBAGALLO I, VANELLA L, DISTEFANO A, et al. Moringa oleifera Lam. improves lipid metabolism during adipogenic differentiation of human stem cells[J]. European Review Formedical and Pharmacological Sciences,2016,20(24):5223−5232.
    [6]
    MAHAJAN S G, MEHTA A. Immunosuppressive activity of ethanolic extract of seeds of Moringa oleifera Lam. in experimental immune inflammation[J]. Journal of Ethnopharmacology,2010,130(1):183−186. doi: 10.1016/j.jep.2010.04.024
    [7]
    MA Z F, AHMAD J, ZHANG H, et al. Evaluation of phytochemical and medicinal properties of Moringa (Moringa oleifera) as a potential functional food[J]. South African Journal of Botany,2020,129:40−46. doi: 10.1016/j.sajb.2018.12.002
    [8]
    WATERMAN C, CHENG D M, ROJAS-SILVA P, et al. Stable, water extractable isothiocyanates from Moringa oleifera leaves attenuate inflammation in vitro[J]. Phytochemistry,2014,103:114−122. doi: 10.1016/j.phytochem.2014.03.028
    [9]
    李杰, 陈超美. CiteSpace: 科技文本挖掘及可视化[M]. 首都经济贸易大学出版社, 2016

    LI J, CHEN C M. CiteSpace: Science and technology text mining and visualization[M]. Capital University of Economics and Business Press, 2016.
    [10]
    陈悦, 陈超美, 刘则渊, 等. CiteSpace知识图谱的方法论功能[J]. 科学学研究,2015,33(2):242−253. [CHEN Y, CHEN C M, LIU Z Y, et al. Methodological function of citespace knowledge graph[J]. Studies in Science of Science,2015,33(2):242−253. doi: 10.3969/j.issn.1003-2053.2015.02.009
    [11]
    AMAGLO N K, BENNETT R N, LO CURTO R B, et al. Profiling selected phytochemicalsand nutrients in different tissues of the multipurpose tree Moringa oleifera L. grown in Ghana[J]. Food Chemistry,2010,122(4):1047−1054. doi: 10.1016/j.foodchem.2010.03.073
    [12]
    ANWAR F, LATIF S, ASHRAF M, et al. Moringa oleifera: A food plant with multiple medicinal uses[J]. Phytotherapy Research,2007,21(1):17−25. doi: 10.1002/ptr.2023
    [13]
    STOHS S J, HARTMAN M J. Review of the safety and efficacy of Moringa oleifera[J]. Phytotherapy Reserch,2015,29(6):796−804. doi: 10.1002/ptr.5325
    [14]
    MBIKAY M. Therapeutic potential of Moringa oleifera leaves in chronic hyperglycemia and dyslipidennia: A review[J]. Frontiers in Pharmacology,2012,3:00024.
    [15]
    ANWAR F, BHANGER M I. Analytical characterization of Moringa oleifera seed oil grown in temperate regions of Pakistan[J]. Journal of Agricultural and Food Chemistry,2003,51(22):6558−6563. doi: 10.1021/jf0209894
    [16]
    LEONE A, SPADA A, BATTEZZATI A, et al. Cultivation, genetic, ethnopharmacology, phytochemistry and pharmacology of Moringa oleifera leaves: An overview[J]. International Journal of Molecular Sciences,2015,16(6):12791−12835.
    [17]
    AWODELE O, OREAGBA I A, ODOMA S, et al. Toxicological evaluation of the aqueous leaf extract of Moringa oleifera Lam. (Moringaceae)[J]. Journal of Ethnopharmacology,2012,139(2):330−336. doi: 10.1016/j.jep.2011.10.008
    [18]
    AL-ASMARI A K, ALBALAWI S M, ATHAR M T, et al. Moringa oleifera as an anti-cancer agent against breast and colorectal cancer cell lines[J]. Plos One,2015,10(8):e01358.
    [19]
    ADEDAPO A A, MOGBOJURI O M, EMIKPE B O. Safety evaluations of the aqueous extract of the leaves of Moringa oleifera in rats[J]. Journal of Medicinal Plants Research,2009,3(8):586−591.
    [20]
    VERGARA-JIMENEZ M, ALMATRAFI M M, FERNANDEZ M L. Bioactive components in Moringa oleifera leaves protect against chronic disease[J]. Antioxidants, 2017, 6(4): 91.
    [21]
    KAR A, CHOUDHARY B K, BANDYOPADHYAY N G. Comparative evaluation of hypoglycaemic activity of some Indian medicinal plants in alloxan diabetic rats[J]. Journal of Ethnopharmacology,2003,84(1):105−108. doi: 10.1016/S0378-8741(02)00144-7
    [22]
    RODRIGUEZ-PEREZ C, QUIRANTES-PINE R, FERNANDEZ-GUTIERREZ A, et al. Optimization of extraction method to obtain a phenolic compounds-rich extract from Moringa oleifera Lam. leaves[J]. Industrial Crops and Products,2015,66:246−254. doi: 10.1016/j.indcrop.2015.01.002
    [23]
    VERMA A R, VIJAYAKUMAR M, MATHELA C S, et al. In vitro and in vivo antioxidant properties of different fractions of Moringa oleifera leaves[J]. Food and Chemical Toxicology,2009,47(9):2196−2201. doi: 10.1016/j.fct.2009.06.005
    [24]
    VONGSAK B, SITHISARN P, MANGMOOL S, et al. Maximizing total phenolics, total flavonoids contents and antioxidant activity of Moringa oleifera leaf extract by the appropriate extraction method[J]. Industrial Crops and Products,2013,44:566−571. doi: 10.1016/j.indcrop.2012.09.021
    [25]
    IQBAL S, BHANGER M I. Effect of season and production location on antioxidant activity of Moringa oleifera leaves grown in Pakistan[J]. Journal of Food Composition and Analysis,2006,19(6):544−551.
    [26]
    KOU X, LI B, OLAYANJU J B, et al. Nutraceutical or pharmacological potential of Moringa oleifera Lam.[J]. Nutrients, 2018, 10(3).
    [27]
    GHASI S, NWOBODO E, OFILI J O. Hypocholesterolemic effects of crude extract of leaf of Moringa oleifera Lam. in high-fat diet fed wistar rats[J]. Journal of Ethnopharmacology,2000,69(1):21−25. doi: 10.1016/S0378-8741(99)00106-3
    [28]
    MAZUMDER U K, GUPTA M, CHAKRABARTI S, et al. Evaluation of hematological and hepatorenal functions of methanolic extract of Moringa oleifera Lam. root treated mice[J]. Indian Journal of Experimental Biology,1999,37(6):612−614.
    [29]
    MEHTA L K, BALARAMAN R, AMIN A H, et al. Effect of fruits of Moringa oleifera on the lipid profile of normal and hypercholesterolaemic rabbits[J]. Journal of Ethnopharmacology,2003,86(2-3):191−195. doi: 10.1016/S0378-8741(03)00075-8
    [30]
    CHUMARK P, KHUNAWAT P, SANVARINDA Y, et al. The in vitro and ex vivo antioxidant properties, hypolipidaemic and antiatherosclerotic activities of water extract of Moringa oleifera Lam. leaves[J]. Journal of Ethnopharmacology,2008,116(3):439−446. doi: 10.1016/j.jep.2007.12.010
    [31]
    LI L F, MA L, WEN Y L, et al. Crude polysaccharide extracted from Moringa oleifera leaves prevents obesity in association with modulating gut microbiota in high-fat diet-fed mice[J]. Frontiers in Nutrition,2022:9.
    [32]
    MABROUKI L, RJEIBI I, TALEB J, et al. Cardiac ameliorative effect of Moringa oleifera leaf extract in high-fat diet-induced obesity in rat model[J]. Biomed Research International,2020:2020.
    [33]
    MAPFUMO M, LEMBEDE B W, NKOMOZEPI P, et al. Crude Moringa oleifera Lam. seed extract attenuates non-alcoholic fatty liver disease in growing Sprague-dawley rats[J]. South Afrcan Journal of Botany,2020,129:191−197. doi: 10.1016/j.sajb.2019.05.026
    [34]
    MUHAMMAD N, IBRAHIM K G, NDHLALA A R, et al. Moringa oleifera Lam. prevents the development of high fructose diet-induced fatty liver[J]. South Afrcan Journal of Botany,2020,129:32−39. doi: 10.1016/j.sajb.2018.12.003
    [35]
    孙朦, 王鸿飞, 王凯凯, 等. 辣木叶黄酮对小鼠血脂调节作用研究[J]. 核农学报,2018,32(8):1597−1602. [SUN M, WANG H F, WANG K K, et al. Study on the effect of Moringa oleifera leaf flavonoids on the regulation of blood lipids in mice[J]. Journal of Nuclear Agricultural Sciences,2018,32(8):1597−1602. doi: 10.11869/j.issn.100-8551.2018.08.1597
    [36]
    杨倩, 田雪梅, 张晓文, 等. 辣木提取物降脂作用的研究[J]. 食品安全质量检测学报,2017,8(3):963−967. [YANG Q, TIAN X M, ZHANG X W, et al. Study on the hypolipidemic effect of Moringa oleifera extract[J]. Journal of Food Safety and Quality Inspection,2017,8(3):963−967. doi: 10.19812/j.cnki.jfsq11-5956/ts.2017.03.044
    [37]
    余建兴. 辣木油提取技术及对大鼠辅助降血脂作用的研究[D]. 昆明: 昆明医学院, 2009

    YU J X. Study on the extraction technique of Moringa oleifera oil and its beneficial effect on blood lipid reduction in rats[D]. Kunming: Kunming Medical College, 2009.
    [38]
    沙子珺, 黎彩凤, 唐仕欢, 等. 新资源药材辣木叶抗高脂血症的药效与作用机制探析[J]. 中国中药杂志,2021,46(14):3465−3477. [SHA Z J, LI C F, TANG S H, et al. Exploration of the efficacy and mechanism of action of the new resource medicinal herb Moringa oleifera against hyperlipidemia[J]. Chinese Journal of Traditional Chinese Medicine,2021,46(14):3465−3477. doi: 10.19540/j.cnki.cjcmm.20210309.401
    [39]
    CHEN G L, XU Y B, WU J L, et al. Hypoglycemic and hypolipidemic effects of Moringa oleifera leaves and their functional chemical constituents[J]. Food Chemistry,2020:333.
    [40]
    王宏, 刘月, 饶露, 等. 辣木籽提取物对高脂血症小鼠血脂及肝脏的影响[J]. 中国油脂,2022,47(7):66−70. [WANG H, LIU Y, RAO L, et al. Effect of Moringa oleifera seed extract on blood lipid and liver in hyperlipidemia mice[J]. China Oils and Fats,2022,47(7):66−70. doi: 10.19902/j.cnki.zgyz.1003-7969.210412
    [41]
    XIE J, WANG Y, JIANG W, et al. Moringa oleifera leaf petroleum ether extract inhibits lipogenesis by activating the AMPK signaling pathway[J]. Frontiers in Pharmacology,2018,9:1447. doi: 10.3389/fphar.2018.01447
    [42]
    EZZAT S M, EL BISHBISHY M H, ABOREHAB N M, et al. Up regulation of MC4R and PPARα expression mediates the anti-obesity activity of Moringa oleifera Lam. in high fatdiet-induced obesity in rats[J]. Journal of Ethnopharmacology,2020:251.
    [43]
    BALUSAMY S R, PERUMALSAMY H, RANJAN A, et al. A dietary vegetable, Moringa oleifera leaves (drumstick tree) induced fat cell apoptosis by inhibiting adipogenesis in 3T3-L1 adipocytes[J]. Journal of Functionanl Foods,2019,59:251−260. doi: 10.1016/j.jff.2019.05.029
    [44]
    KIM D, CHOI M, SHIN H. Extracts of Moringa oleifera leaves from different cultivation regions show both antioxidant and antiobesity activities[J]. Journal of Food Biochemistry,2020,44(7):e13282.
    [45]
    SWAMY G M, RAMESH G, PRASAD R D, et al. Astragalin, (3-O-glucoside of kaempferol), isolated from Moringa oleifera leaves modulates leptin, adiponectin secretion and inhibits adipogenesis in 3T3-L1 adipocytes[J]. Archives of Physiology and Biochemistry,2020,128:938−944.
    [46]
    UKIYA M, MOTEGI K, SATO D, et al. Effect of compounds from Moringa oleifera Lam. on in vitro non-alcoholic fatty liver disease (NAFLD) model system[J]. Chemistry & Biodiversity,2021,18(7):e210024.
    [47]
    SANGKITIKOMOL W, ROCEJANASAROJ A, TENCOMNAO T. Effect of Moringa oleifera on advanced glycation end-product formation and lipid metabolism gene expression in HepG2 cells[J]. Genetics and Molecular Research,2014,13(1):723−735. doi: 10.4238/2014.January.29.3
    [48]
    JAJA-CHIMEDZA A, ZHANG L, WOLFF K, et al. A dietary isothiocyanate-enriched moringa (Moringa oleifera) seed extract improves glucose tolerance in a high-fat-diet mouse model and modulates the gut microbiome[J]. Journal of Functional Foods,2018,47:376−385. doi: 10.1016/j.jff.2018.05.056
    [49]
    WANG F, BAO Y, SI J, et al. The beneficial effects of a polysaccharide from Moringa oleifera leaf on gut microecology in mice[J]. Journal of Medicinal Food,2019,22(9):907−918. doi: 10.1089/jmf.2018.4382
    [50]
    JAISWAL D, RAI P K, KUMAR A, et al. Effect of Moringa oleifera Lam. leaves aqueous extract therapy on hyperglycemic rats[J]. Journal of Ethnopharmacology,2009,123(3):392−396. doi: 10.1016/j.jep.2009.03.036
    [51]
    LEONE A, BERTOLI S, DI L S, et al. Effect of Moringa oleifera leaf powder on postprandial blood glucose response: In vivo study on saharawi people living in refugee camps[J]. Nutrients, 2018, 10:10.
    [52]
    KHAN W, PARVEEN R, CHESTER K, et al. Hypoglycemic potential of aqueous extract of Moringa oleifera leaf and in vivo GC-MS metabolomics[J]. Frontiers in Pharmacology,2017:8.
    [53]
    MAGAJI U F, SACAN O, YANARDAG R. Alpha amylase, alpha glucosidase and glycation inhibitory activity of Moringa oleifera extracts[J]. South African Journal of Botany,2020,128:225−230. doi: 10.1016/j.sajb.2019.11.024
    [54]
    ADISAKWATTANA S, CHANATHONG B. Alpha-glucosidase inhibitory activity and lipid-lowering mechanisms of Moringa oleifera leaf extract[J]. European Review for Medical and Pharmacological Sciences,2011,15(7):803−808.
    [55]
    BIN A S, ANSARI P, AZAM S, et al. Anti-hyperglycaemic activity of Moringa oleifera is partly mediated by carbohydrase inhibition and glucose-fibre binding[J]. Bioscience Reports,2017,37(3):BSR20170059−BSR20170059.
    [56]
    TSHABALALA T, NDHLALA A R, NCUBE B, et al. Potential substitution of the root with the leaf in the use of Moringa oleifera for antimicrobial, antidiabetic and antioxidant properties[J]. South African Journal of Botany,2020,129:106−112. doi: 10.1016/j.sajb.2019.01.029
    [57]
    SUBRAMANIAM S, ROSDI M H B, KUPPUSAMY U R. Customized cooking methods enhance antioxidant, antiglycemic, and insulin-like properties of momordica charantiaand Moringa oleifera[J]. Journal of Food Quality,2017,2017:1−9.
    [58]
    王远, 郑雯, 袁田青, 等. 辣木叶总黄酮微波辅助提取工艺优化及其抑制α-葡萄糖苷酶活性研究[J]. 核农学报,2018,32(1):84−94. [WANG Y, ZHENG W, YUAN T Q, et al. Optimization of microwave-assisted extraction process of total flavonoids from Moringa oleifera leaves and its inhibition of α-glucosidase activity[J]. Journal of Nuclear Agricultural Sciences,2018,32(1):84−94. doi: 10.11869/j.issn.100-8551.2018.01.0084
    [59]
    OLAYAKI L A, IREKPITA J E, YAKUBU M T, et al. Methanolic extract of Moringa oleifera leaves improves glucose tolerance, glycogen synthesis and lipid metabolism in alloxan-induced diabetic rats[J]. Journal of Basic and Clinical Physiology and Pharmacology,2015,26(6):585−593.
    [60]
    ABD E L A, EL B B E S, MAHBOUB H D, et al. Moringa oleifera leaf extract ameliorates alloxan-induced diabetes in rats by regeneration of beta cells and reductionof pyruvate carboxylase expression[J]. Biochemistry and Cell Biology,2014,92(5):413−419. doi: 10.1139/bcb-2014-0081
    [61]
    吉莉莉. 辣木叶黄酮提取分离纯化及其主要成分异槲皮苷降血糖活性与机理研究[D]. 成都: 四川农业大学, 2015

    JI L L. Extraction, purification and hypoglycemic activity and mechanism of isoquercitrin, the main component of Moringa oleifera leaf flavonoids[D]. Chengdu: Sichuan Agricultural University, 2015.
    [62]
    HAFIZUR R M, MARYAM K, HAMEED A, et al. Insulin releasing effect of some pure compounds from Moringa oleifera on mice islets[J]. Medicinal Chemistry Reserch,2018,27(5):1408−1418. doi: 10.1007/s00044-018-2157-1
    [63]
    ATTAKPA E S, SANGARE M M, BEHANZIN G J, et al. Moringa oleifera Lam. stimulatesactivation of the insulin-dependent akt pathway antidiabetic effect in a diet-induced obesity (DIO) mouse model[J]. Folia Biologca,2017,63(2):42−51.
    [64]
    HUANG Q, LIU R, LIU J, et al. Integrated network pharmacology analysis and experimental validation to reveal the mechanism of anti-insulin resistance effects of Moringa oleifera seeds[J]. Drug Design Development and Therapy,2020,14:4069−4084. doi: 10.2147/DDDT.S265198
    [65]
    KAJIHARA R, NAKATSU S, SHIONO T, et al. Antihypertensive effect of water extracts from leaves of Moringa oleifera Lam. on spontaneously hypertensive rats[J]. Journal of the Japanese Society for Food Science and Technology-Nippon Shokuhin Kagaku Kogaku Kaishi,2008,55(4):183−185. doi: 10.3136/nskkk.55.183
    [66]
    ABROGOUA D P, DANO D S, MANDA P, et al. Effect on blood pressure of a dietary supplement containing traditional medicinal plants of côted’ Ivoire[J]. Journal of Ethnopharmacology,2012,141(3):840−847. doi: 10.1016/j.jep.2012.03.022
    [67]
    ACURAM L K, HERNANDEZ C L C. Anti-hypertensive effect of Moringa oleifera Lam[J]. Cogent Biology,2019,5(1):1596526. doi: 10.1080/23312025.2019.1596526
    [68]
    ADERINOLA T A, FAGBEMI T N, ENUJIUGHA V N, et al. In vitro antihypertensive and antioxidative properties of alcalase-derived Moringa oleifera seed globulin hydrolysate and its membrane fractions[J]. Journal of Food Processing and Preservation, 2019, 43(2): e13862.
    [69]
    陈冰冰, 欧颖仪, 叶灏铎, 等. 富硒辣木叶蛋白ACE抑制肽的酶解工艺优化及活性研究[J]. 食品工业科技,2022,43(3):1−9. [CHEN B B, OU Y Y, YE J Z, et al. Optimization of enzymatic process and activity study of ACE inhibitory peptide of selenium-rich Moringa oleifera leaf protein[J]. Science and Technology of Food Industry,2022,43(3):1−9. doi: 10.13386/j.issn1002-0306.2021060268
    [70]
    RANDRIAMBOAVONJY J I, RIO M, PACAUD P, et al. Moringa oleifera seeds attenuate vascular oxidative and nitrosative stresses in spontaneously hypertensive rats[J]. Oxidative Medicine and Cellular Longevity,2017,2017:4129459.
    [71]
    AEKTHAMMARAT D, PANNANGPETCH P, TANGSUCHARIT P. Moringa oleifera leaf extract lowers high blood pressure by alleviating vascular dysfunction and decreasing oxidative stress in L-NAME hypertensive rats[J]. Phytomedicine,2019,54:9−16. doi: 10.1016/j.phymed.2018.10.023
    [72]
    ATTAKPA E S, BERTIN G A, CHABI N W, et al. Moringa oleifera-rich diet and t cell calcium signaling in spontaneously hypertensive rats[J]. Physiology Reserch,2017,66(5):753−767.
    [73]
    NURHAYATI N, CLARA M K, SITI M, et al. The effect of moringa capsule and moringa tea consumption on the elderly's uric acid level[J]. Indian Journal of Public Health Research & Development,2019,10(3):1061−1065.
    [74]
    钟英英, 周佳明, 叶美凤, 等. 辣木叶提取物对黄嘌呤氧化酶活性的抑制[J]. 食品工业,2020,41(11):55−58. [ZHONG Y Y, ZHOU J M, YE M F, et al. Inhibition of moringa leaf extract on xanthine oxidase activity[J]. Food Industry,2020,41(11):55−58.
    [75]
    TIAN Y, LIN L, ZHAO M, et al. Xanthine oxidase inhibitory activity and antihyperuricemic effect of Moringa oleifera Lam. leaf hydrolysate rich in phenolics and peptides[J]. Journal of Ethnopharmacology,2021,270:113808. doi: 10.1016/j.jep.2021.113808
    [76]
    梁文娟, 和劲松, 田洋, 等. 辣木叶提取物降低高尿酸血症小鼠尿酸水平及机理研究[J]. 安徽农业科学,2017,45(17):108−109, 112. [LIANG W J, HE J S, TIAN Y. et al. Study on the reduction of uric acid level and mechanism of hyperuricemic mice by Moringa oleifera leaf extract[J]. Journal of Anhui Agricultural Sciences,2017,45(17):108−109, 112. doi: 10.3969/j.issn.0517-6611.2017.17.037
    [77]
    GIDAMIS A, PANGA J, SARWATT S, et al. Nutrient and antinutrient contents in raw and cooked young leaves and immature pods of Moringa oleifera Lam[J]. Ecology of Food and Nutrition,2003,42(6):399−411. doi: 10.1080/03670240390268857
    [78]
    GOVENDER L, SIIWELA M. The effect of Moringa oleifera leaf powder on the physical quality, nutritional composition and consumer acceptability of white and brown breads[J]. Foods,2020,9(12):19.
    [79]
    OGUNSINA B S, RADHA C, INDRANI D. Quality characteristics of bread and cookies enriched with debittered Moringa oleifera seed flour[J]. International Journal of Food Sciences and Nutrition,2011,62(2):185−194. doi: 10.3109/09637486.2010.526928
    [80]
    BISANZ J E, ENOS M K, PRAYGOD G, et al. Microbiota at multiple body Sites during pregnancy in a rural tanzanian population and effects of moringa-supplemented probiotic yogurt[J]. Applied and Environmental Microbiology,2015,81(15):4965−4975. doi: 10.1128/AEM.00780-15
    [81]
    BOATENG L, QUARPONG W, OHEMENG A, et al. Effect of complementary foods fortified with Moringa oleifera leaf powder on hemoglobin concentration and growth of infants in the Eastern Region of Ghana[J]. Food Science & Nutrition,2019,7(1):302−311.
    [82]
    GAMBO A, MOODLEY I, BABASHANI M, et al. A double-blind, randomized controlled trial to examine the effect of Moringa oleifera leaf powder supplementation on the immune status and anthropometric parameters of adult HIV patients on antiretroviral therapy in a resource-limited setting[J]. Plos One, 2021, 16(12): e0261935.
    [83]
    TSHINGANI K, DONNEN P, MUKUMBI H, et al. Impact of Moringa oleifera Lam. leaf powder supplementation versus nutritional counseling on the body mass index and immune response of HIV patients on antiretroviral therapy: A single-blind randomized control trial[J]. Bmc Complementary and Alternative Medicine,2017,17(1):420.
    [84]
    PILOTOS J, IBRAHIM K A, MOWA C N, et al. Moringa oleifera treatment increases Tbet expression in CD4+ T cells and remediates immune defects of malnutrition in Plasmodium chabaudi-infected mice[J]. Malaria Journal,2020,19(1):62.
  • Cited by

    Periodical cited type(11)

    1. 苏敏,李红丽,白亚敏,黄大亮,刘元,吴彦蕾. 基于液相色谱-串联高分辨质谱技术的食品中污染物检测技术研究进展. 食品安全质量检测学报. 2025(04): 44-52 .
    2. 张君. 我国南方部分地区蓝莓种植过程中农药残留检测结果分析. 河北农机. 2024(03): 136-138 .
    3. 张申平,秦宇,顾颖娟. QuEChERS-超高效液相色谱-四极杆/静电场轨道阱质谱法测定牛羊乳及其乳粉中21种兽药. 乳业科学与技术. 2024(02): 24-29 .
    4. 李红洲,国果,李博岩,梁桂娟,李志远. 超高效液相色谱-四极杆-飞行时间-高分辨质谱法分析6种李果实中的代谢物差异性. 食品安全质量检测学报. 2024(11): 63-73 .
    5. 刘宇航,于寒冰,杨红菊,马啸,温雅君,孙志伟,习佳林,熊慧勤,肖志勇. 高效液相色谱-四极杆-飞行时间质谱法快速筛查蔬菜中124种药物与个人护理品残留量. 食品安全质量检测学报. 2024(16): 175-184 .
    6. 朱春雨,吴移山,郑景娇. 高效液相色谱-串联质谱法测定鸡蛋中地克珠利、妥曲珠利及其代谢物残留量. 食品安全质量检测学报. 2024(16): 211-218 .
    7. 肖泳,曾小明,李政,袁列江,邓航,王淑霞,潘照. 超高效液相色谱-四极杆/静电场轨道阱高分辨质谱法测定鸡蛋中94种农药残留. 食品与发酵工业. 2024(21): 333-340 .
    8. 王颖怡,吴玉田,孟春杨,周贻兵,刘利亚. HPLC-MS/MS技术同时测定鸡蛋中5种抗球虫药. 食品工业. 2023(06): 291-294 .
    9. 李晓慧,李建洪,王洪萍,金芬. 植物源性食品中化学性危害物质的色谱-质谱检测技术研究进展. 分析测试学报. 2023(10): 1357-1369 .
    10. 周雪莼,胡婷婷,王佳慧,白静,杨颖,侯宇,张哲,张勋. 高效液相色谱-高分辨质谱法快速筛查动物源性药食同源产品中32种抗生素兽药残留. 吉林中医药. 2023(12): 1469-1474 .
    11. 范轶欧,迟英欣,杨路平,焦燕妮. 高分辨质谱技术在环境和食品风险物质非靶向筛查检测中应用的研究进展. 预防医学论坛. 2023(12): 955-960 .

    Other cited types(0)

Catalog

    Article Metrics

    Article views (251) PDF downloads (14) Cited by(11)

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return