Effects of Low Glycemic Index Noodles on Glucose/Lipid Metabolism in Diabetic Mice

YU Mengling; ZHANG Sanshan; ZHANG Qiao; HE Yujie; LI Xian; LEI Ji

doi:10.13386/j.issn1002-0306.2022020071

Volume 43 Issue 23

Nov. 2022

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Science and Technology of Food Industry > 2022 > 43(23): 353-359. > DOI: 10.13386/j.issn1002-0306.2022020071

YU Mengling, ZHANG Sanshan, ZHANG Qiao, et al. Effects of Low Glycemic Index Noodles on Glucose/Lipid Metabolism in Diabetic Mice[J]. Science and Technology of Food Industry, 2022, 43(23): 353−359. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2022020071.

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Effects of Low Glycemic Index Noodles on Glucose/Lipid Metabolism in Diabetic Mice

School of Food and Bioengineering, Xihua University, Chengdu 610000, China

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Received Date: February 13, 2022
Available Online: October 07, 2022

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Abstract

Abstract

Objective: To evaluate the effect of low-glycemic index (GI) noodles on improving glucose and lipid metabolism in diabetic mice induced by streptozotocin (STZ). Methods: Diabetic male Kunming mice were induced by STZ, the intervention group was fed with low GI noodles for 7 weeks, the glucose and lipid metabolism index were measured, and compared with the model control group fed with normal noodles. Results: Compared with the diabetic mice in the model group, the body weight, serum insulin (INS) and liver glycogen levels increased significantly (P<0.05) in the intervention group. The glycated serum proteins (GSP), fasting glucose and organ index were decreased significantly (P<0.05). Oral glucose tolerance, liver and pancreatic tissue damage improved significantly (P<0.05), lipid levels showed a trend of improvement. Conclusion: Low GI noodles had an improvement effect on hyperglycemia symptoms and lipid metabolism disorders in diabetic mice, which could provide some reference for the development and application of low GI food.
- glycemic index,
- diabetes,
- sugar metabolism,
- lipid metabolism,
- noodles

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References

[1]	PUNTHAKEE Z, GOLDENBERG R, KATZ P. Definition, classification and diagnosis of diabetes, prediabetes and metabolic syndrome[J]. Canadian Journal of Diabetes,2018,42:S10−S15.
[2]	MELLO V D D, LAAKSONEN D E. Dietary fibers: Current trends and health benefits in the metabolic syndrome and type 2 diabetes[J]. Arquivos Brasileiros De Endocrinologia & Metabologia,2009,53(5):09−18.
[3]	RESHMI S K, SUDHA M L, SHASHIREKHA M N. Starch digestibility and predicted glycemic index in the bread fortified with pomelo (Citrus maxima) fruit segments[J]. Food Chemistry,2017,23:957−965.
[4]	钟雪婷, 康建平, 华苗苗, 等. 基于血糖生成指数的最新应用研究进展[J]. 粮油食品科技,2020,28(2):66−72. [ZHONG X T, KANG J P, HUA M M, et al. Recent advances in research on applications based on glycemic index[J]. Grain, Oil and Food Technology,2020,28(2):66−72.
[5]	杨小雪. 红小豆淀粉消化性及血糖生成指数的影响因素研究[D]. 北京: 中国农业科学院, 2020 YANG X X. Study on the factors affecting the digestibility and glycemic index of red small bean starch[D]. Beijing: The Chinese Academy of Agricultural Sciences, 2020.
[6]	SALMERÓN J, MANSON J E, STAMPFER M J, et al. Dietary fiber, glycemic load, and risk of non-insulin-dependent diabetes mellitus in women[J]. JAMA,1997,277(6):472−477. doi: 10.1001/jama.1997.03540300040031
[7]	AROCHA G M, GOMEZ M, ROSELL C M. Impact of legume flours on quality and in vitro digestibility of starch and protein from gluten-free cakes[J]. Food and Bioprocess Technology,2012,5(8):3142−3150. doi: 10.1007/s11947-011-0642-3
[8]	RYU H-S, ZENG J. Determining the optimal recipe for long-grain jasmine rice with sea tangle laminaria japonica, and its effect on the glycemic index[J]. Fisheries and Aquatic Sciences,2014,17(1):47−57. doi: 10.5657/FAS.2014.0047
[9]	JUN Y, BAE I Y, LEE S, et al. Utilisation of preharvest dropped apple peels as a flour substitute for a lower glycaemic index and higher fibre cake[J]. International Journal of Food Sciences and Nutrition,2014,65(1):62−68. doi: 10.3109/09637486.2013.830083
[10]	陈宇航, 于克学, 王敏, 等. 超细豆渣粉面包的研制及其血糖生成指数的测定[J]. 食品科技,2016(10):133−138. [CHEN Y H, YU K X, WANG M, et al. Development of super fine bean residue powder bread and its determination of glycemic index[J]. Food Technology,2016(10):133−138.
[11]	张宗颖. 低血糖生成指数杂粮复合馒头的研制及临床效果观察[D]. 张家口: 河北北方学院, 2019 ZHANG Z Y. Development and clinical effect of hypoglycemia index[D]. Zhangjiakou: Hebei Northern College, 2019.
[12]	韩小存. 低血糖指数豆类品种的筛选及其在面制品中的应用[D]. 郑州: 河南工业大学, 2013 HAN X C. Screening of hypoglycemic index bean varieties and their application in noodle products[D]. Zhengzhou: Henan University of Technology, 2013.
[13]	王佳, 黄桂颖, 陈海光. 天然食品的降糖作用及其研究进展天然食品的降糖作用及其研究进展[J]. 仲恺农业工程学院学报,2017,30(2):58−63. [WANG J, HUANG G Y, CHEN H G. The hypoglycemic effect and research progress of natural foods and its research progress[J]. Journal of Zhongkai College of Agricultural Engineering,2017,30(2):58−63. doi: 10.3969/j.issn.1674-5663.2017.02.010
[14]	胡玲, 张俊, 雷激. 紫甘蓝挂面制备的关键技术研究[J]. 食品科技,2019,44(11):185−191. [HU L, ZHANG J, LEI J. Research on the key techniques for the preparation of purple cabbage hanging noodles[J]. Food Technology,2019,44(11):185−191.
[15]	高雅君. 低血糖指数馒头加工工艺及其功能特性研究[D]. 郑州: 河南工业大学, 2018 GAO Y J. Study on the processing process and functional characteristics of low-glycaemic index steamed bread with hypoglycemic index[D]. Zhengzhou: Henan University of Technology, 2018.
[16]	王波. 番石榴叶提取物辅助降血糖作用及其机制研究[D]. 成都: 四川大学, 2007 WANG B. Guava leaf extract-assisted hypoglycemic effect and its mechanism study[D]. Chengdu: Sichuan University, 2007.
[17]	秦川, 邓巍, 徐艳峰, 等. 实验动物比较组织学彩色图谱[M]. 科学出版社, 2017, 25(3): 1−249 QIN C, DENG W, XU Y F, et al. Comparative histology color atlas of laboratory animals[M]. Science Press, 2017, 25(3): 1−249.
[18]	中华医学会糖尿病学分会. 中国2型糖尿病防治指南(2020年版)[J]. 国际内分泌代谢杂志,2021,41(5):482−548. [Diabetes Branch of Chinese Medical Association. Chinese guidelines for the prevention and treatment of type 2 diabetes mellitus (2020 edition)[J]. International Journal of Endocrinology and Metabolism,2021,41(5):482−548. doi: 10.3760/cma.j.cn121383-20210825-08063
[19]	李耀冬, 叶静, 肖美添. 复方海藻膳食纤维对糖尿病小鼠降血糖作用的研究[J]. 食品工业科技,2014,35(10):341−345. [LI Y D, YE J, XIAO M T. Study on the hypoglycemic effect of compound seaweed dietary fiber in diabetic mice[J]. Food Industry Technology,2014,35(10):341−345.
[20]	曾山容, 邓小敏, 易倍吉, 等. 中医药治疗2型糖尿病血脂异常的研究进展[J]. 大众科技,2021,23(4):73−75. [ZENG S R, DENG X M, YI B J, et al. Research progress in TCM treatment of type 2 DM dyslipidemia[J]. Mass Technology,2021,23(4):73−75. doi: 10.3969/j.issn.1008-1151.2021.04.022
[21]	邹亚兰, 张卫兵, 贺有元, 等. 大柴胡汤对2型糖尿病合并肥胖患者血糖及血脂水平的影响[J]. 现代医学与健康研究电子杂志,2021,5(9):18−20. [ZOU Y L, ZHANG W B, HE Y Y, et al. Effect of Dacpleurum Tang on blood glucose and lipid levels in patients with type 2 diabetes and obesity[J]. Electronic Journal of Modern Medicine and Health Research,2021,5(9):18−20.
[22]	赵薇, 崔焕波. 糖化血清白蛋白检测在糖调节受损及新诊断糖尿病人群中的临床意义[J]. 中外医疗,2015,34(9):195−196. [ZHAO W, CUI H B. Clinical significance of glycated serum albumin detection in people with impaired glucose regulation and newly diagnosed diabetes mellitus[J]. Chinese and Foreign Medical Care,2015,34(9):195−196. doi: 10.3969/j.issn.1674-0742.2015.09.091
[23]	张慧, 洪雁, 顾正彪, 等. 3种谷物全粉中淀粉的消化性及影响因素[J]. 食品与发酵工业,2012,38(11):26−31. [ZHANG H, HONG Y, GU Z B, et al. Digestive properties and influencing factors of starch in the whole flour of 3 grains[J]. Food and Fermentation Industry,2012,38(11):26−31.
[24]	程林, 陈斌, 蔡宝昌. 山药及其麸炒品的多糖部位对小鼠免疫功能的影响[J]. 中药新药与临床药理,2006,17(2):86−89. [CHENG L, CHEN B, CAI B C. Effect of the polysaccharide site of Chinese yam and its bran fry on the immune function in mice[J]. New Drugs and Clinical Pharmacology of Traditional Chinese Medicine,2006,17(2):86−89. doi: 10.3321/j.issn:1003-9783.2006.02.002
[25]	ZHAO G, KAN J, LI Z, et al. Structural features andimmunological activity of a polysaccharide from Dioscorea opposita Thunb roots[J]. Carbohydrate Polymers,2005,61(2):125−131. doi: 10.1016/j.carbpol.2005.04.020
[26]	张敏. 荞麦凉茶工艺研究及其对Ⅱ型糖尿病小鼠降血糖作用[D]. 杨凌: 西北农林科技大学, 2014 ZHANG M. Study on buckwheat herbal tea technology and its hypoglycemic effect in type diabetic mice[D]. Yangling: Northwest A & F University, 2014.
[27]	缪铭, 江波, 张涛. Kabuli和Desi品种鹰嘴豆淀粉结构及功能性质[J]. 吉林大学学报(工学版),2008(6):1495−1500. [MIU M, JIANG B, ZHANG T. Structural and functional properties of the Kabuli and Desi varieties of chickpea starch[J]. Journal of Jilin University (Engineering Edition),2008(6):1495−1500.
[28]	DAVISON K M, TEMPLE N J. Cereal fiber, fruitfiber, and type 2 diabetes: Explaining the paradox[J]. Journal of Diabetes and Its Complications,2018,32(2):240−245. doi: 10.1016/j.jdiacomp.2017.11.002
[29]	彭晓蝶, 秦樱瑞, 黄先智, 等. 桑叶-苦瓜混合粉对糖尿病小鼠的降糖作用[J]. 现代食品科技,2017,33(4):31−37. [PENG X D, QIN Y R, HUANG X Z, et al. The hypoglycemic effect of mulberry leaf-bitter gourd mixed powder on diabetic mice[J]. Modern Food Technology,2017,33(4):31−37.
[30]	夏晴, 王箴言, 王玉, 等. 桦褐孔菌多糖对糖尿病小鼠的干预作用及机制[J]. 中国食品学报,2021,21(3):71−78. [XIA Q, WANG Z Y, WANG Y, et al. Intervention and mechanism of Betcinola polysaccharides in diabetic mice[J]. Chinese Journal of Food Products,2021,21(3):71−78.
[31]	张宇, 姜毓君, 党芳芳, 等. 副干酪乳杆菌TD062对Ⅱ型糖尿病小鼠的降糖作用[J]. 中国食品学报,2020,20(5):106−112. [ZHANG Y, JIANG Y J, DANG F F, et al. The hypoglycemic effect of L. paracasei TD062 in type diabetic mice[J]. Chinese Journal of Food Products,2020,20(5):106−112.

[1]	cover[J]. Science and Technology of Food Industry, 2022, 43(24).
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[3]	cover[J]. Science and Technology of Food Industry, 2022, 43(19).
[4]	cover[J]. Science and Technology of Food Industry, 2022, 43(18).
[5]	cover[J]. Science and Technology of Food Industry, 2022, 43(17).
[6]	cover[J]. Science and Technology of Food Industry, 2022, 43(13).
[7]	cover[J]. Science and Technology of Food Industry, 2022, 43(11).
[8]	Cover[J]. Science and Technology of Food Industry, 2022, 43(9).
[9]	cover[J]. Science and Technology of Food Industry, 2022, 43(8).
[10]	cover[J]. Science and Technology of Food Industry, 2022, 43(7).