Current Advances in Neuroprotective Effects and Relative Mechanisms of Sesamin

JIANG Deqi; MO Juanfeng; BIN Shuilian; TUO Yinting; LI Ziqiang; LI Xinyi; LIANG Ruilan

doi:10.13386/j.issn1002-0306.2021080048

Volume 43 Issue 16

Aug. 2022

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Science and Technology of Food Industry > 2022 > 43(16): 452-457. > DOI: 10.13386/j.issn1002-0306.2021080048

JIANG Deqi, MO Juanfeng, BIN Shuilian, et al. Current Advances in Neuroprotective Effects and Relative Mechanisms of Sesamin[J]. Science and Technology of Food Industry, 2022, 43(16): 452−457. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2021080048.

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Current Advances in Neuroprotective Effects and Relative Mechanisms of Sesamin

1.
College of Biology and Pharmacy, Yulin Normal University, Yulin 537000, China
2.
Bioengineering & Technology Center for Native Medicinal Resources Development, Yulin Normal University, Yulin 537000, China
3.
Guangxi Key Laboratory of Agricultural Resources Chemistry and Biotechnology, Yulin 537000, China

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Received Date: August 04, 2021
Available Online: June 07, 2022

Graphical Abstract

Abstract

Abstract

Sesamin is an important lignan compound, which is mainly isolated from sesame seeds. Sesamin has a variety of biological activities such as anti-oxidative stress, anti-inflammatory, anti-apoptosis, reducing β-amyloid aggregation, anti-excitatory toxicity, promoting dopamine production and neurotrophic factor expression. Sesamin can effectively prevent and treat Alzheimer's disease, Parkinson's disease, traumatic brain injury, depression and anxiety, cerebral ischemia injury and other neuropsychiatric diseases at the animal and cellular levels. In this paper, the neuroprotective effects and related mechanisms of sesamin in vivo and in vitro experiments are reviewed in order to provide scientific basis for the development and application of sesamin-related health care products and food additives.
- sesamin,
- oxidative stress,
- anti-inflammatory,
- Alzheimer's disease,
- neuroprotective

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References (50)

References

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