Development and Application Progress of Food for Special Medical Purpose for Phenylketonuria

LU Chenhui; HE Yongxi; WEI Haodong; FENG Yongwei; GAO Hui; SHI Xueli; ZHANG Yi

doi:10.13386/j.issn1002-0306.2021070262

Volume 43 Issue 16

Aug. 2022

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Science and Technology of Food Industry > 2022 > 43(16): 413-420. > DOI: 10.13386/j.issn1002-0306.2021070262

LU Chenhui, HE Yongxi, WEI Haodong, et al. Development and Application Progress of Food for Special Medical Purpose for Phenylketonuria[J]. Science and Technology of Food Industry, 2022, 43(16): 413−420. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2021070262.

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Development and Application Progress of Food for Special Medical Purpose for Phenylketonuria

LU Chenhui^1,,
HE Yongxi¹,
WEI Haodong¹,
FENG Yongwei^{2, 3, ,},
GAO Hui⁴,
SHI Xueli⁴,
ZHANG Yi^1, ,

1.
State Key Laboratory of Food Science and Technology, Jiangnan University, Institute of Analytical Food Safety, School of Food Science, Wuxi 214122, China
2.
Wuxi Food Safety Inspection and Testing Center, Wuxi 214100, China
3.
National Market Supervision Technology Innovation Center (Special Food), Wuxi 214131, China
4.
Shijiazhuang Maternal and Child Health Hospital, Shijiazhuang 050051, China

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Received Date: July 22, 2021
Available Online: June 04, 2022

Graphical Abstract

Abstract

Abstract

Patients with phenylketonuria (PKU) have to restrict the intake of phenylalanine (Phe) or its structural analogues for life because of the genetic defect that prevents them from metabolizing Phe normally. Therefore, the research and development of food for special medical purpose for PKU is important to protect the health of patients and improve their quality of life. This paper reviews the dietary regimen for patients with PKU, focusing on special low-protein foods, low-Phe foods, and food for special medical purpose based on glycomacropeptides, and details the sources or preparation techniques and functional properties of these foods, and look into future research directions and research priorities to address the current problems of single product form and poor palatability in this field, with a view to providing a better understanding of the development of food for special medical purpose for PKU. The research direction and focus of future research are also presented to provide reference for the research and development of food for special medical purpose for PKU.
- phenylketonuria,
- low protein,
- glycomacropeptide,
- low phenylalanine peptide,
- food for special medical purpose

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References

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Development and Application Progress of Food for Special Medical Purpose for Phenylketonuria