Research Progress on the Regulation Mechanisms of Insulin Secretion by Plant Active Ingredients

ZHANG Xiaoyun; ZHANG Xueqin; MEI Xiaohong

doi:10.13386/j.issn1002-0306.2020080236

Volume 42 Issue 16

Aug. 2021

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Science and Technology of Food Industry > 2021 > 42(16): 412-420. > DOI: 10.13386/j.issn1002-0306.2020080236

ZHANG Xiaoyun, ZHANG Xueqin, MEI Xiaohong. Research Progress on the Regulation Mechanisms of Insulin Secretion by Plant Active Ingredients[J]. Science and Technology of Food Industry, 2021, 42(16): 412−420. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2020080236.

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Research Progress on the Regulation Mechanisms of Insulin Secretion by Plant Active Ingredients

Key Laboratory of Safety Assessment of Genetically Modified Organism (Food Safety), Ministry of Agriculture and Rural Affairs, College of Food Science and Nutrition Engineering, China Agricultural University, Beijing 100083, China

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Received Date: August 23, 2020
Available Online: June 10, 2021

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Abstract

Abstract

The dysfunction of pancreatic insulin secretion is an important pathophysiological basis of diabetes mellitus and the active ingredients extracted from plants have the ability to regulate insulin secretion in the body. These active ingredients mainly include polysaccharides, flavonoids, terpenes, polyphenols, alkaloids and so on. Compared with oral hypoglycemic drugs on insulin secretion, the plant active ingredients regulating insulin secretion has the characteristics of low toxicity and small side effects, which arouses an extensive attention to their hypoglycemic research and development at home and abroad. This paper reviews the research models and regulation mechanisms of insulin secretion by natural plant active ingredients in recent years, which aims to provide scientific reference for the development of nature glucose-lowering products.
- diabetes mellitus,
- plant active ingredients,
- insulin,
- model,
- regulation mechanism

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