Citation: | BAO Hairong, CHEN Baike. Preparation of Solid Dispersion and Its Application in Functional Food[J]. Science and Technology of Food Industry, 2021, 42(16): 397−403. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2020080152. |
[1] |
Sekiguchi K, Obi N. Studies on absorption of eutectic mixture. i. a comparison of the behavior of eutectic mixture of sulfathiazole and that of ordinary sulfathiazole in man[J]. Chem Pharm Bull,1961,9(11):866−872. doi: 10.1248/cpb.9.866
|
[2] |
Sanjay Kshirsagar, Manisha Choudhari, Reshmi Sathyan, et al. Solubility enhancement by various techniques based on pharmaceutical and medicinal chemistry approach: An overview[J]. Asian Journal of Pharmacy and Technology,2019,9(2):141−146. doi: 10.5958/2231-5713.2019.00024.2
|
[3] |
Scott V Jermain, Chris Brough, Robert O Williams. Amorphous solid dispersions and nanocrystal technologies for poorly water-soluble drug delivery-An update[J]. International Journal of Pharmaceutics,2018,535(1-2):379−392. doi: 10.1016/j.ijpharm.2017.10.051
|
[4] |
刘建平, 生物药剂学与药物动力学[M]. 第4版. 北京: 人民卫生出版社, 2011: 125−130.
|
[5] |
曹文. 药物制剂新技术在现代中药研究中的应用[J]. 临床合理用药志,2019,12(26):165−166.
|
[6] |
李范珠, 李永吉. 中药药剂学[M]. 北京: 人民卫生出版社, 2012: 30−50.
|
[7] |
Kawabata Y, Wada K, Nakatani M, et al. Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: Basic approaches and practical applications[J]. Int J Pharm,2011,420(1):1−10. doi: 10.1016/j.ijpharm.2011.08.032
|
[8] |
Bertoni S, Albertini B, Passerini N. Spray congealing: An emerging technology to prepare solid dispersions with enhanced oral bioavailability of poorly water soluble drugs[J]. Molecules,2019,24(19):3471. doi: 10.3390/molecules24193471
|
[9] |
李美云, 雷小小, 周江, 等. 星点设计-效应面法优化莲心总碱固体分散体渗透泵控释片处方[J]. 中草药,2016(47):3210.
|
[10] |
Antónia Gonçalves, Nooshin Nikmaram, Shahin Roohinejad, et al. Production, properties, and applications of solid self-emulsifying delivery systems (s-seds) in the food and pharmaceutical industries[J]. Colloids & Surfaces A Physicochemical & Engineering Aspects,2018,538:108−126.
|
[11] |
Schittny A, Philipp-bauer S, Detampel P, et al. Mechanistic insights into effect of surfactants on oral bioavailability of amorphous solid dispersions[J]. Journal of Controlled Release,2020,320:214−225. doi: 10.1016/j.jconrel.2020.01.031
|
[12] |
马诗经. 姜黄素固体制剂制备及其抗炎作用与机理研究[D]. 广东: 广东工业大学, 2016.
|
[13] |
李美琪. 大黄素和白屈菜红碱的固体化学研究[D]. 上海: 中国科学院大学(中国科学院上海药物研究所), 2019.
|
[14] |
李安. L-硒-甲基硒代半胱氨酸固体分散体的制备及在牛奶中的应用[D]. 江西: 南昌大学, 2014.
|
[15] |
Li M, Meng F, Tsutsumi Y, et al. Understanding molecular interactions in rafoxanide-povidone amorphous solid dispersions from ultrafast magic angle spinning nmr[J]. Molecular Pharmaceutics,2020,17(6):2196−2207. doi: 10.1021/acs.molpharmaceut.0c00317
|
[16] |
Cunha R H, Nele M, Dias M L. Reaction and thermal behavior of vitrimer-like polyhydroxy esters based on polyethylene glycol diglycidyl ether[J]. Journal of Applied Polymer Science,2020,137(43):e49329. doi: 10.1002/app.49329
|
[17] |
Lee, Ping I, Sun, et al. Probing the mechanisms of drug release from amorphous solid dispersions in medium-soluble and medium-insoluble carriers[J]. Journal of Controlled Release: Official Journal of the Controlled Release Society,2015,211:85−93. doi: 10.1016/j.jconrel.2015.06.004
|
[18] |
Nieto K, Mallery S R, Schwendeman S P. Microencapsulation of amorphous solid dispersions of fenretinide enhances drug solubility and release from plga in vitro and in vivo[J]. International Journal of Pharmaceutics,2020:119475.
|
[19] |
崔福德. 药剂学[M]. 第7版. 北京: 人民卫生出版社, 2012: 230−240.
|
[20] |
吴玉小, 白长喜. 关于固体分散技术[J]. 内蒙古中医药,2013,32(7):132−134. doi: 10.3969/j.issn.1006-0979.2013.07.116
|
[21] |
Bera S, Maity S, Ghosh B, et al. Development and characterization of solid dispersion system for enhancing the solubility and dissolution rate of dietary capsaicin[J]. Current Drug Therapy,2020,15(2):143−151. doi: 10.2174/1574885514666190724143351
|
[22] |
N Zajc, A Obreza, M Bele. Physical properties and dissolution behaviour of nifedipine/mannitol solid dispersions prepared by hot melt method[J]. Int J Pharm,2005,291:51−58. doi: 10.1016/j.ijpharm.2004.07.042
|
[23] |
Chen B, Wang X, Zhang Y, et al. Improved solubility, dissolution rate, and oral bioavailability of main biflavonoids fromSelaginella doederleinii extract by amorphous solid dispersion[J]. Drug Delivery,2020,27(1):309−322. doi: 10.1080/10717544.2020.1716876
|
[24] |
Alhijjaj M, Yassin S, Reading M, et al. Characterization of heterogeneity and spatial distribution of phases in complex solid dispersions by thermal analysis by structural characterization and x-ray micro computed tomography[J]. Pharmaceutical Research,2017,34(5):971−989. doi: 10.1007/s11095-016-1923-3
|
[25] |
Vo L N, Park C, Lee B J. Current trends and future perspectives of solid dispersions containing poorly water-soluble drugs[J]. European Journal of Pharmaceutics & Biopharmaceutics Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E V,2013,85(3):799−813.
|
[26] |
Chauhan H, Hui-Gu C, Atef E. Correlating the behavior of polymers in solution as precipitation inhibitor to its amorphous stabilization ability in solid dispersions[J]. Journal of Pharmaceutical Sciences,2013,102(6):1924−1935. doi: 10.1002/jps.23539
|
[27] |
Bialleck S, Rein H. Preparation of starch-based pellets by hot-melt extrusion[J]. European Journal of Pharmaceutics & Biopharmaceutics Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E V,2011,79(2):440−448.
|
[28] |
Roya Ghanavati, Azade Taheri, Alireza Homayouni. Anomalous dissolution behavior of celecoxib in pvp/isomalt solid dispersions prepared using spray drier[J]. Materials Science & Engineering C Materials for Biological Applications,2017,72:501.
|
[29] |
游国叶, 樊轻亚, 杜晶, 等. Formulation optimization of capsaicin solid dispersion and its characterization[J]. 中国药房,2019,30(11):1464−1469.
|
[30] |
徐德锋, 刘亚林, 王文杰, 等. 二甲基姜黄素固体分散体的制备及表征[J]. 中国医药工业杂志,2019,50(2):82−87.
|
[31] |
Chen Yuejie, Wang Shujing, Wang Shan, et al. Sodium lauryl sulfate competitively interacts with hpmc-as and consequently reduces oral bioavailability of posaconazole/hpmc-as amorphous solid dispersion[J]. Molecular Pharmaceutics,2016,13(8):2787−2795. doi: 10.1021/acs.molpharmaceut.6b00391
|
[32] |
Sinha S, Ali M, Baboota S, et al. Solid dispersion as an approach for bioavailability enhancement of poorly water-soluble drug ritonavir[J]. Aaps Pharmscitech,2010,11(2):518−527. doi: 10.1208/s12249-010-9404-1
|
[33] |
Bisharat L, Alkhatib H S, Abdelhafez A, et al. Hot melt extruded zein for controlled delivery of diclofenac sodium: Effect of drug loading and medium composition[J]. International Journal of Pharmaceutics,2020:119503.
|
[34] |
Marcos Bonilla-Hernández, Zapata-Catzin G A, Omar de Jesús Castillo-Cruz, et al. Synthesis and characterization of metformin-pluronic based polyurethanes for controlled drug delivery[J]. International Journal of Polymeric Materials,2020:1−12.
|
[35] |
Nagi A S, Chatlapalli R S, Hasan S, et al. Compositions containing micronized tanaproget prepared by wet granulation: US20060247234 A1[P]. US 2014.
|
[36] |
张锴, 王珂, 徐英楠, 等. 基于固体分散技术的山楂叶总黄酮缓释胶囊的研制及释药机制研究[J]. 中国现代应用药学,2017(3):78−84.
|
[37] |
李庆国, 关世侠, 郭慧珍. 水飞蓟素缓释片的制备及体外释药机制研究[J]. 中国药房,2013,24(19):1770−1772. doi: 10.6039/j.issn.1001-0408.2013.19.15
|
[38] |
Kolašinac N, Kachrimanis K, Homšek I, et al. Solubility enhancement of desloratadine by solid dispersion in poloxamers[J]. International Journal of Pharmaceutics,2012,436(1-2):161−170. doi: 10.1016/j.ijpharm.2012.06.060
|
[39] |
Sahoo N G, Kakran M, Li L, et al. Dissolution enhancement of a poorly water-soluble antimalarial drug by means of a modified multi-fluid nozzle pilot spray drier[J]. Materials Science & engineering,2011,31(2):391−399.
|
[40] |
Verhoeven E, Beer T R M D, Schacht E, et al. Influence of polyethylene glycol/polyethylene oxide on the release characteristics of sustained-release ethylcellulose mini-matrices produced by hot-melt extrusion: In vitro and in vivo evaluations[J]. European Journal of Pharmaceutics & Biopharmaceutics,2009,72(2):430−470.
|
[41] |
Maniruzzaman M, Boateng J S, Bonnefille M, et al. Taste masking of paracetamol by hot-melt extrusion: anin vitro and in vivo evaluation[J]. European Journal of Pharmaceutics & Biopharmaceutics Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E V,2012,80(2):433−442.
|
[42] |
Moes J, Koolen S, Huitema A, et al. Development of an oral solid dispersion formulation for use in low-dose metronomic chemotherapy of paclitaxel[J]. European Journal of Pharmaceutics & Biopharmaceutics,2013,83(1):87−94.
|
[43] |
Haley McFall, Sandeep Sarabua, Vijaykumar Shankar, et al. Formulation of aripiprazole-loaded pH-modulated solid dispersions via hot-melt extrusion technology: In vitro and in vivo studies[J]. International Journal of Pharmaceutics,2019,554:302−311. doi: 10.1016/j.ijpharm.2018.11.005
|
[44] |
王腾飞, 张先华, 王丽. 阿奇霉素固体分散体制备工艺研究[J]. 中国药业,2020,29(3):31−34. doi: 10.3969/j.issn.1006-4931.2020.03.009
|
[45] |
Hwang I, Kang C Y, Park J B. Advances in hot-melt extrusion technology toward pharmaceutical objectives[J]. Journal of Pharmaceutical Investigation,2017,47(2):123−132. doi: 10.1007/s40005-017-0309-9
|
[46] |
Repka M A, Bandari S, Kallakunta V R, et al. Melt extrusion with poorly soluble drugs-An integrated review[J]. International Journal of Pharmaceutics,2018,535(1-2):68−85.
|
[47] |
Repka M A, Shah S, Lu J, et al. Melt extrusion: process to product[J]. Expert Opinion on Drug Delivery,2012,9(1):105−125. doi: 10.1517/17425247.2012.642365
|
[48] |
Djuris J, Milovanovic S, Medarevic D, et al. Selection of the suitable polymer for supercritical fluid assisted preparation of carvedilol solid dispersions[J]. International Journal of Pharmaceutics,2018:65.
|
[49] |
Ehsan Adeli. A comparative evaluation between utilizing sas supercritical fluid technique and solvent evaporation method in preparation of azithromycin solid dispersions for dissolution rate enhancement[J]. The Journal of Supercritical Fluids,2014:87.
|
[50] |
Fromme A, Fischer C, Keine K, et al. Characterization and correlation of mobile phase dispersion of aqueous-organic solvent systems in centrifugal partition chromatography[J]. Journal of Chromatography A,2020:460990.
|
[51] |
Tong H H Y, Du Z, Wang G N, et al. Spray freeze drying with polyvinylpyrrolidone and sodium caprate for improved dissolution and oral bioavailability of oleanolic acid, a bcs class IV compound[J]. International Journal of Pharmaceutics,2011,404(1−2):148−158. doi: 10.1016/j.ijpharm.2010.11.027
|
[52] |
Lili Fitriani, Irma Afriyanti, Afriyani, et al. Solid dispersion of usnic acid-hpmc 2910 prepared by spray drying and freeze drying techniques[J]. Oriental Journal of Chemistry,2018,34(4):2083−2088. doi: 10.13005/ojc/3404048
|
[53] |
Motallae S, Taheri A, Homayouni A. Preparation and characterization of solid dispersions of celecoxib obtained by spray-drying ethanolic suspensions containing pvp-k30 or isomalt[J]. Journal of Drug Delivery Science and Technology,2018,46:188−196. doi: 10.1016/j.jddst.2018.05.020
|
[54] |
Shah N, Sandhu H, Phuapradit W, et al. Development of novel microprecipitated bulk powder (mbp) technology for manufacturing stable amorphous formulations of poorly soluble drugs[J]. International Journal of Pharmaceutics,2012,438(53-60).
|
[55] |
Nishikawa R, Aridome N, Ojima N, et al. Structure and properties of fiber-reinforced polypropylene prepared by direct incorporation of aqueous solution of poly(vinyl alcohol)[J]. Polymer,2020,199:122566. doi: 10.1016/j.polymer.2020.122566
|
[56] |
Dong Z, Chatterji A, Sandhu H, et al. Evaluation of solid state properties of solid dispersions prepared by hot-melt extrusion and solvent co-precipitation[J]. International Journal of Pharmaceutics,2008,355(1-2):141−149. doi: 10.1016/j.ijpharm.2007.12.017
|
[57] |
牛晓磊, 贾润霞, 谈秀凤. 橙皮苷磷脂复合物固体分散体的制备、表征及其体内药动学研究[J]. 中成药,2020,42(9):2255−2259. doi: 10.3969/j.issn.1001-1528.2020.09.002
|
[58] |
赵强, 武倩, 刘喜纲. 齐墩果酸固体分散体的制备[J]. 中成药,2018,40(10):2170−2176. doi: 10.3969/j.issn.1001-1528.2018.10.011
|
[59] |
Shen X X, Branford-White C, White K, et al. Oral fast-dissolving drug delivery membranes prepared from electrospun polyvinylpyrrolidone ultrafine fibers[J]. Nanotechnology,2009,20(5):55104. doi: 10.1088/0957-4484/20/5/055104
|
[60] |
Kawakami K. Miscibility analysis of particulate solid dispersions prepared by electrospray deposition[J]. International Journal of Pharmaceutics,2012,433(1-2):71−78. doi: 10.1016/j.ijpharm.2012.04.082
|
[61] |
Yu D G, Yang J M, Branford-white C, et al. Third generation solid dispersions of ferulic acid in electrospun composite nanofibers[J]. International Journal of Pharmaceutics,2010,400(1-2):158−164. doi: 10.1016/j.ijpharm.2010.08.010
|
[62] |
Balogh A, Farkas B, Palvolgyi A, et al. Novel alternating current electrospinning of hydroxypropylmethylcellulose acetate succinate (HPMCAS) nanofibers for dissolution enhancement: the importance of solution conductivity[J]. J Pharm Sci,2017,106(6):1634−1643. doi: 10.1016/j.xphs.2017.02.021
|
[63] |
Nagy Z K, Balogh A, B Démuth, et al. High speed electrospinning for scaled-up production of amorphous solid dispersion of itraconazole[J]. Int J Pharm,2015,480(1−2):137−142. doi: 10.1016/j.ijpharm.2015.01.025
|
[64] |
谭佳威, 孙如煜, 曾滟棱, 等. 固体分散技术在制剂领域的研究进展[J]. 药物评价研究,2017,40(8):1182−1188.
|
[65] |
马艳秋, 曲韵智, 李津明. 固体分散体老化现象与抗老化的研究进展[J]. 中国新药杂志,2007,16(6):442−446. doi: 10.3321/j.issn:1003-3734.2007.06.006
|
[66] |
王文月, 陈菊明, 庄珊珊, 等. 防止固体分散体老化的研究进展[J]. 中国医院药学杂志,2014,34(21):1858−1861.
|
[67] |
Venecia W, Lou X C, Osterling D J, et al. Relationship between amorphous solid dispersion in vivo absorption andin vitro dissolution: Phase behavior during dissolution, speciation, and membrane mass transport[J]. Control Release,2018,292(3):172−182.
|
[68] |
Large M J, Ogilvie S P, King A A K. Understanding solvent spreading for langmuir deposition of nanomaterial films: A hansen solubility parameter approach[J]. Langmuir,2017,33(51):14766−14771. doi: 10.1021/acs.langmuir.7b03867
|
[69] |
Hormann T E, Jager N, Funke A, et al. Formulation per- formance and processability window for manufacturing a dual-polymer amorphous solid dispersion via hot-melt extrusion and strand pelletization[J]. Int J Pharm,2018,553(1-2):408−421. doi: 10.1016/j.ijpharm.2018.10.035
|
[70] |
刘旭, 温新国, 缪旭, 等. 固体分散体物理稳定性影响因素及抗老化研究进展[J]. 中国现代应用药学,2011,28(8):710−717.
|
[71] |
Yang J, Grey K, Doney J. An improved kinetics approach to describe the physical stability of amorphous solid dispersions[J]. Int J Pharm,2010,384(1-2):24−31. doi: 10.1016/j.ijpharm.2009.09.035
|
[72] |
张佳佳, 朱源, 余江南, 等. 辛香料挥发油类化学成分的新型载体系统研究进展[J]. 中国中药杂志,2015,40(20):3932−3936.
|
[73] |
时念秋, 张勇, 冯波, 等. 不同制备工艺制得姜黄素固体分散体的性质比较研究[J]. 中国药学杂志,2016,v. 51(10):49−54.
|
[74] |
索炜. 大黄酸固体分散体在大鼠体内药物动力学和药效学的研究[D]. 河北: 河北联合大学, 2011.
|
[75] |
姜修婷. 基于固体分散技术的叶黄素片的制备及评价[D]. 山东: 青岛科技大学, 2018.
|
[76] |
陈钊, 蒋建中, 崔正刚. 表面活性剂-纳米颗粒相互作用与智能体系的构建(Ⅱ)相反电荷表面活性剂-纳米颗粒相互作用(i)——开关转移构建开关性Pickering乳状液和Pickering泡沫[J]. 日用化学工业,2019,49(8):492−502. doi: 10.3969/j.issn.1001-1803.2019.08.002
|
[77] |
田诗伟, 毛国梁, 张珈瑜, 等. 开关型Pickering乳液体系[J]. 化学进展,2020,32(4):434−453.
|
[78] |
王然, 张春玉, 刘洋, 等. 淀粉微粒和酪蛋白酸钠协同稳定Pickering乳状液性质研究[J]. 食品科学,,2020,41(12):60−65.
|
[79] |
曹亚倩, 肖军霞, 蒋林宏, 等. 玉米纤维素在Pickering乳液制备中的应用研究[J]. 中国粮油学报,2020,35(4):54−60. doi: 10.3969/j.issn.1003-0174.2020.04.010
|
1. |
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