Research Progress in Preparation and Application of Emulsion Microgel Particle

YAN Wenjia; JIA Xin; YAN Jinxin; YIN Lijun

doi:10.13386/j.issn1002-0306.2020070201

Volume 42 Issue 15

Jul. 2021

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Science and Technology of Food Industry > 2021 > 42(15): 383-388. > DOI: 10.13386/j.issn1002-0306.2020070201

YAN Wenjia, JIA Xin, YAN Jinxin, et al. Research Progress in Preparation and Application of Emulsion Microgel Particle[J]. Science and Technology of Food Industry, 2021, 42(15): 383−388. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2020070201.

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Research Progress in Preparation and Application of Emulsion Microgel Particle

College of Food Science and Technology, China Agricultural University, Beijing 100083, China

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Received Date: July 16, 2020
Available Online: May 31, 2021

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Abstract

Abstract

Lipophile active molecules such as vitamins, fatty acids and essential oils are sensitive to oxygen, heat and light, and are easy to be oxidized and degraded during food process or physiological transportation, which limit their application in food industry. Among the technologies that can be used to deliver lipophilic molecules, emulsion microgel particles, relatively new soft solid particle delivery systems, have attracted increasing attention due to their discrete size and smart release characteristics. Encapsulation of lipophilic active molecules by emulsion microgel particles can significantly improve the physicochemical stability of lipophilic molecules. Moreover, emulsion microgel particles can release effectively the lipophilic active molecules at targeted locations to improve their bioavailability. In this paper, the domestic and foreign literatures about emulsion microgel particle delivery carriers are summarized. The preparation, controlled release property and main applications of emulsion microgel particle delivery carriers are emphatically discussed. At last, the current problems and future development of emulsion microgel particle delivery systems of lipophilic molecules are analyzed and prospected, aiming to provide reference for the application of emulsion microgel particle in food industry.
- emulsion microgel particle,
- preparation,
- lipophilic molecule,
- delivery system

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References

[1]	Prakash A, Baskaran R, Paramasivam N, et al. Essential oil based nanoemulsions to improve the microbial quality of minimally processed fruits and vegetables: A review[J]. Food Research International,2018,111:509−523. doi: 10.1016/j.foodres.2018.05.066
[2]	刘贝, 陆剑锋, 姜绍通, 等. 维生素D₂明胶微球的制备工艺研究及性能表征[J]. 中国食品添加剂,2017(5):68−74. doi: 10.3969/j.issn.1006-2513.2017.05.005
[3]	汪鸿. 微胶囊技术在高不饱和脂肪酸油脂中的研究进展[J]. 食品安全导刊,2017(33):37. doi: 10.3969/j.issn.1674-0270.2017.33.025
[4]	Wei Z, Huang Q. Assembly of protein-polysaccharide complexes for delivery of bioactive ingredients: A perspective paper[J]. Journal of Agricultural and Food Chemistry,2019,67(5):1344−1352. doi: 10.1021/acs.jafc.8b06063
[5]	Bao C, Jiang P, Chai J, et al. The delivery of sensitive food bioactive ingredients: Absorption mechanisms, influencing factors, encapsulation techniques and evaluation models[J]. Food Research International,2019,120:130−140. doi: 10.1016/j.foodres.2019.02.024
[6]	Torres O, Murray B, Sarkar A. Design of novel emulsion microgel particles of tuneable size[J]. Food Hydrocolloids,2017,71:47−59. doi: 10.1016/j.foodhyd.2017.04.029
[7]	Lin D, Kelly A L, Miao S. Preparation, structure-property relationships and applications of different emulsion gels: Bulk emulsion gels, emulsion gel particles, and fluid emulsion gels[J]. Trends in Food Science & Technology,2020,102:123−137.
[8]	Harper J M, Clark J P. Food extrusion[J]. Critical Reviews in Food Science & Nutrition,1979,11(2):155−215.
[9]	Egan T, O’Riordan D, O’Sullivan M, et al. Cold-set whey protein microgels as pH modulated immobilisation matrices for charged bioactives[J]. Food Chemistry,2014,156:197−203. doi: 10.1016/j.foodchem.2014.01.109
[10]	Lin D, Kelly A L, Maidannyk V, et al. Effect of concentrations of alginate, soy protein isolate and sunflower oil on water loss, shrinkage, elastic and structural properties of alginate-based emulsion gel beads during gelation[J]. Food Hydrocolloids,2020:105998.
[11]	Sung M R, Xiao H, Decker E A, et al. Fabrication, characterization and properties of filled hydrogel particles formed by the emulsion-template method[J]. Journal of Food Engineering,2015,155:16−21. doi: 10.1016/j.jfoodeng.2015.01.007
[12]	Egan T, Jacquier J C, Rosenberg Y, et al. Cold-set whey protein microgels for the stable immobilization of lipids[J]. Food Hydrocolloids,2013,31(2):317−324. doi: 10.1016/j.foodhyd.2012.11.008
[13]	Moakes R J A, Sullo A, Norton I T. Preparation and rheological properties of whey protein emulsion fluid gels[J]. RSC Advances,2015,5(75):60786−60795. doi: 10.1039/C5RA12684C
[14]	Moakes R J A, Sullo A, Norton I T. Preparation and characterisation of whey protein fluid gels: The effects of shear and thermal history[J]. Food Hydrocolloids,2015,45:227−235. doi: 10.1016/j.foodhyd.2014.11.024
[15]	McClements D J. Enhanced delivery of lipophilic bioactives using emulsions: A review of major factors affecting vitamin, nutraceutical, and lipid bioaccessibility[J]. Food & Function,2018,9(1):22−41.
[16]	Laing D G, Jinks A. Flavour perception mechanisms[J]. Trends in Food Science & Technology,1996,7(12):387−389.
[17]	Corstens M N, Berton-Carabin C C, Elichiry-Ortiz P T, et al. Emulsion-alginate beads designed to controlin vitro intestinal lipolysis: Towards appetite control[J]. Journal of Functional Foods,2017,34:319−328. doi: 10.1016/j.jff.2017.05.003
[18]	Wang M, Doi T, Hu X, et al. Influence of ionic strength on the thermostability and flavor (allyl methyl disulfide) release profiles of calcium alginate microgels[J]. Food Hydrocolloids,2019,93:24−33. doi: 10.1016/j.foodhyd.2019.02.013
[19]	Torres O, Murray B S, Sarkar A. Overcomingin vitro gastric destabilisation of emulsion droplets using emulsion microgel particles for targeted intestinal release of fatty acids[J]. Food Hydrocolloids,2019,89:523−533. doi: 10.1016/j.foodhyd.2018.11.010
[20]	Ma D, Tu Z C, Wang H, et al. Microgel-in-microgel biopolymer delivery systems: Controlled digestion of encapsulated lipid droplets under simulated gastrointestinal conditions[J]. Journal of Agricultural and Food Chemistry,2018,66(15):3930−3938. doi: 10.1021/acs.jafc.8b00132
[21]	Bokkhim H, Bansal N, Grøndahl L, et al. In-vitro digestion of different forms of bovine lactoferrin encapsulated in alginate micro-gel particles[J]. Food Hydrocolloids,2016,52:231−242. doi: 10.1016/j.foodhyd.2015.07.007
[22]	Hasanvand E, Fathi M, Bassiri A, et al. Novel starch based nanocarrier for vitamin D fortification of milk: Production and characterization[J]. Food and Bioproducts Processing,2015,96:264−277. doi: 10.1016/j.fbp.2015.09.007
[23]	Kuhn K R, E Silva F G D, Netto F M, et al. Production of whey protein isolate-gellan microbeads for encapsulation and release of flaxseed bioactive compounds[J]. Journal of Food Engineering,2019,247:104−114. doi: 10.1016/j.jfoodeng.2018.12.002
[24]	Deng Y, Zhong G, Wang Y, et al. Quality by design approach for the preparation of fat-soluble vitamins lipid injectable emulsion[J]. International Journal of Pharmaceutics,2019,571:118717. doi: 10.1016/j.ijpharm.2019.118717
[25]	Ozturk B, Argin S, Ozilgen M, et al. Nanoemulsion delivery systems for oil-soluble vitamins: Influence of carrier oil type on lipid digestion and vitamin D₃ bioaccessibility[J]. Food Chemistry,2015,187:499−506. doi: 10.1016/j.foodchem.2015.04.065
[26]	Rejinold N S, Kim H K, Isakovic A F, et al. Therapeutic vitamin delivery: Chemical and physical methods with future directions[J]. Journal of Controlled Release,2019,298:83−98. doi: 10.1016/j.jconrel.2019.01.038
[27]	Wang B, Vongsvivut J, Adhikari B, et al. Microencapsulation of tuna oil fortified with the multiple lipophilic ingredients vitamins A, D₃, E, K₂, curcumin and coenzyme Q10[J]. Journal of Functional Foods,2015,19:893−901. doi: 10.1016/j.jff.2015.03.027
[28]	Teng Z, Luo Y, Wang Q. Carboxymethyl chitosan-soy protein complex nanoparticles for the encapsulation and controlled release of vitamin D₃[J]. Food Chemistry,2013,141(1):524−532. doi: 10.1016/j.foodchem.2013.03.043
[29]	Eratte D, Dowling K, Barrow C J, et al. Recent advances in the microencapsulation of omega-3 oil and probiotic bacteria through complex coacervation: A review[J]. Trends in Food Science & Technology,2018,71:121−131.
[30]	刘婷婷, 石少侠, 段虎平, 等. 亚麻籽营养成分提取及其功能和应用研究进展[J]. 中国油脂,2020(3):20.
[31]	Bakry A M, Huang J, Zhai Y, et al. Myofibrillar protein with κ-or λ-carrageenans as novel shell materials for microencapsulation of tuna oil through complex coacervation[J]. Food Hydrocolloids,2019,96:43−53. doi: 10.1016/j.foodhyd.2019.04.070
[32]	Abbasi F, Samadi F, Jafari S M, et al. Production of omega-3 fatty acid-enriched broiler chicken meat by the application of nanoencapsultsed flaxseed oil prepared via ultrasonication[J]. Journal of Functional Foods,2019,57:373−381. doi: 10.1016/j.jff.2019.04.030
[33]	Wang B, Adhikari B, Barrow C J. Optimisation of the microencapsulation of tuna oil in gelatin-sodium hexametaphosphate using complex coacervation[J]. Food Chemistry,2014,158:358−365. doi: 10.1016/j.foodchem.2014.02.135
[34]	Hashim A F, Hamed S F, Hamid H A A, et al. Antioxidant and antibacterial activities of omega-3 rich oils/curcumin nanoemulsions loaded in chitosan and alginate-based microbeads[J]. International Journal of Biological Macromolecules,2019,140:682−696. doi: 10.1016/j.ijbiomac.2019.08.085
[35]	Alleleyn A M E, Van Avesaat M, Troost F J, et al. Gastrointestinal nutrient infusion site and eating behavior: Evidence for a proximal to distal gradient within the small intestine?[J]. Nutrients,2016,8(3):117. doi: 10.3390/nu8030117
[36]	Chen F, Deng Z, Zhang Z, et al. Controlling lipid digestion profiles using mixtures of different types of microgel: Alginate beads and carrageenan beads[J]. Journal of Food Engineering,2018,238:156−163. doi: 10.1016/j.jfoodeng.2018.06.009
[37]	Guo Q, Ye A, Lad M, et al. Impact of colloidal structure of gastric digesta on in-vitro intestinal digestion of whey protein emulsion gels[J]. Food Hydrocolloids,2016,54:255−265. doi: 10.1016/j.foodhyd.2015.10.006
[38]	Guo Q, Bellissimo N, Rousseau D. Role of gel structure in controlling in vitro intestinal lipid digestion in whey protein emulsion gels[J]. Food Hydrocolloids,2017,69:264−272. doi: 10.1016/j.foodhyd.2017.01.037
[39]	Dias C B, Zhu X, Thompson A K, et al. Effect of the food form and structure on lipid digestion and postprandial lipaemic response[J]. Food & Function,2019,10(1):112−124.
[40]	Fuhrmann P L, Sala G, Stieger M, et al. Effect of oil droplet inhomogeneity at different length scales on mechanical and sensory properties of emulsion-filled gels: Length scale matters[J]. Food Hydrocolloids,2020,101:105462. doi: 10.1016/j.foodhyd.2019.105462
[41]	Lin D, Kelly A L, Maidannyk V, et al. Effect of structuring emulsion gels by whey or soy protein isolate on the structure, mechanical properties, andin-vitro digestion of alginate-based emulsion gel beads[J]. Food Hydrocolloids,2020:106165.
[42]	Valdivieso-Ugarte M, Gomez-Llorente C, Plaza-Díaz J, et al. Antimicrobial, antioxidant, and immunomodulatory properties of essential oils: A systematic review[J]. Nutrients,2019,11(11):2786. doi: 10.3390/nu11112786
[43]	Doost A S, Nasrabadi M N, Kassozi V, et al. Recent advances in food colloidal delivery systems for essential oils and their main components[J]. Trends in Food Science & Technology,2020,99:474−486.
[44]	Reineccius G A. Flavor encapsulation[J]. Food Reviews International,1989,5(2):147−176. doi: 10.1080/87559128909540848
[45]	Kwan A, Davidov-Pardo G. Controlled release of flavor oil nanoemulsions encapsulated in filled soluble hydrogels[J]. Food Chemistry,2018,250:46−53. doi: 10.1016/j.foodchem.2017.12.089
[46]	Shetta A, Kegere J, Mamdouh W. Comparative study of encapsulated peppermint and green tea essential oils in chitosan nanoparticles: Encapsulation, thermal stability, in-vitro release, antioxidant and antibacterial activities[J]. International Journal of Biological Macromolecules,2019,126:731−742. doi: 10.1016/j.ijbiomac.2018.12.161

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