Research Progress on the Utilization of Vitamin C Against Type 2 Diabetes

DING Lina; WANG Zhibin; WANG Yao; NING Jie; ZHANG Xiandang; DING Wenyu

doi:10.13386/j.issn1002-0306.2020070147

Volume 42 Issue 15

Jul. 2021

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Science and Technology of Food Industry > 2021 > 42(15): 372-376. > DOI: 10.13386/j.issn1002-0306.2020070147

DING Lina, WANG Zhibin, WANG Yao, et al. Research Progress on the Utilization of Vitamin C Against Type 2 Diabetes[J]. Science and Technology of Food Industry, 2021, 42(15): 372−376. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2020070147.

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Research Progress on the Utilization of Vitamin C Against Type 2 Diabetes

1.
Endocrine and Metabolic Diseases Hospital of Shandong First Medical University(Shandong Institute of Endocrine and Metabolic Diseases), Jinan 250062, China
2.
Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250062, China

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Received Date: July 13, 2020
Available Online: May 31, 2021

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Abstract

Abstract

Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder caused by insulin deficiency and insulin resistance.Vitamin C (V_C) is an essential nutrient for human body. Vc is an antioxidant to protect cells from oxidative stress. Oxidative stress state played an important role in the occurrence and development of T2DM and its complications. Appropriate supplementation of V_C can reduce the risk of T2DM and complications. Recent studies has shown that V_C is closely related to the occurrence of T2DM and its complications. The evidence is that plasma V_C levels are generally low in patients with T2DM and inversely associated with the risk of T2DM. Supplementation of V_C in T2DM patients can improve insulin resistance and inflammation, and also reduce the risk of diabetic nephropathy and cardiovascular disease, but there is no significant improvement in diabetic periodontal disease. This paper summarizes the role of V_C in the occurrence and development of T2DM and its complications, with the purpose of providing reference for the prevention and treatment of T2DM.
- vitamin C,
- type 2 diabetes,
- oxidative stress,
- free radicals,
- antioxidants

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References (50)

References

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