Research Progress of <i>in Vitro</i> Models for Bioaccessibility and Bioavailability and Their Applications in Food Contaminants Exposure Assessment

XU Feifei; LI Yueqi; LIN Jun; LAI Yuefei; CHI Huiqin; WU Weiliang; YANG Xingfen

doi:10.13386/j.issn1002-0306.2020070049

Volume 42 Issue 13

Jun. 2021

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Science and Technology of Food Industry > 2021 > 42(13): 395-403. > DOI: 10.13386/j.issn1002-0306.2020070049

XU Feifei, LI Yueqi, LIN Jun, et al. Research Progress of in Vitro Models for Bioaccessibility and Bioavailability and Their Applications in Food Contaminants Exposure Assessment[J]. Science and Technology of Food Industry, 2021, 42(13): 395−403. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2020070049.

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Research Progress of in Vitro Models for Bioaccessibility and Bioavailability and Their Applications in Food Contaminants Exposure Assessment

1.
Food Safety and Health Research Center, Guangdong Provincial Key Laboratory of Tropical Disease Research, Guangdong-Hongkong-Macao Joint Laboratory for Contaminants Exposure and Health, School of Public Health, Southern Medical University, Guangzhou 510515, China
2.
Department of Preventive Medicine, Faculty of Medical Science, Jinan University, Guangzhou 510632, China

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Received Date: July 05, 2020
Available Online: April 26, 2021

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Abstract

Abstract

With the new generation of toxicity test method technology feasible in different fields, its application in food safety risk assessment further improves the accuracy of exposure assessment. The key correction factors introduced in the process of food assessment, such as bioaccessibility and bioavailability of contaminants, can provide more precise essential data for food safety management, including food safety control and food safety standard establishment and revision. Accordingly, this paper reviews and compares various in vitro alternative models and their applications for bioaccessibility and bioavailability in food risk assessment of chemical contaminants, and presents an outlook on the future of new methods and technologies, to provide a methodological reference for accurate assessment of the exposure of chemical contaminants via dietary.
- bioaccessibility,
- bioavailability,
- in vitro model,
- chemical contaminant,
- risk assessment

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