Abstract: Response surface analysis was used to optimize the conditions in grass carp surimi-based products processing.First, Plackett-Burman design was adopted to screen out three important factors affecting the gel strengh of grass carp surimi-based products:washing time, the time of ultrasonic treatmen and chopping time.Then steepest ascent path was adopted to approach the optimal region, and last the Box-Behnken design and response surface analysis were used to determine the optimal levels of the main factors.As a result, the optimal conditions were analyzed as:washing time of 15min, the time of ultrasonic treatmen of 43min, chopping time 15min.Under optimal conditions, the gel strengh of grass carp surimi-based products was 1308.67g·cm-1, which was as 1.46 times as that under the original processing.