The stability and inhibitory effect of F5-SPs derived from sericin peptides on α-Glucosidase

Tooking the inhibitory activity of F5-SPs derived from serine peptides on α-glucosidaseas the investigated index,the effects of temperature,pH,time of ultraviolet and artificial digestion on the stability of F5-SPs were investigated. The results showed that F5-SPs were stable at higher temperatures(>37 ℃). In the case of strong acid and strong alkali,the inhibitory activity of F5-SPs on α-glucosidase was significantly reduced. The effect of UV irradiation on F5-SPs was moderate. In addition,the F5-SPs had a certain degree of loss of α-glucosidase inhibitory activity after treatment with two kinds of artificial digestive solution. Sericin peptide F5-SPs has a certain toleranceon the temperature,pH,ultraviolet and artificial digestive solution. The result showed that the newly discovered F5-SPs derived from serine peptides with α-glucosidase inhibitory activity had a certain tolerance to temperature,pH,ultraviolet and artificial digestive solution,and had great potential for application and development.