WANG Ran, LI Jian, LI Chen-chen, LIU Ning, LIU Tao. Optimization of ultrasonic-assisted ethanol extraction of total flavonoids from Pinus koraiensis needles by response surface methodology[J]. Science and Technology of Food Industry, 2018, 39(4): 143-149.
Citation: WANG Ran, LI Jian, LI Chen-chen, LIU Ning, LIU Tao. Optimization of ultrasonic-assisted ethanol extraction of total flavonoids from Pinus koraiensis needles by response surface methodology[J]. Science and Technology of Food Industry, 2018, 39(4): 143-149.

Optimization of ultrasonic-assisted ethanol extraction of total flavonoids from Pinus koraiensis needles by response surface methodology

More Information
  • Received Date: June 05, 2017
  • Available Online: December 25, 2020
  • The aim of this paper was to extract the total flavonoids from Xiaoxing’anling Pinus koraiensis needles by ultrasonic assisted ethanol extraction method,and to achieve the purpose of rational utilization of the Northeast Pinus koraiensis needles. The ratio of material to liquid,volume fraction of ethanol,ultrasonic temperature,ultrasonic time were set as the main influencing factors,based on the single factor experiment,the total flavonoid yield was taken as the object of study,Box-Behnken center combination design and response surface methodology were used to optimize the extraction process of total flavonoids from Pinus koraiensis needles. The results showed that when the ratio of material to liquid was 1:52 g/mL,the volume fraction of ethanol was 51%,the ultrasonic temperature was 76 ℃ and the time was 103 min,the yield of total flavonoids was about 5.82%.The process conditions are reasonable and reliable,which provides a theoretical basis for industrial production and extraction.
  • Related Articles

    [1]MAHETIJIANG·Maolidan, WANG Junlong, NUERXIATI·Rehebati, LI Ziwei. Based on Network Pharmacology, Molecular Docking and Experiments to Explore the Anti-gastric Cancer Effect of Apigenin[J]. Science and Technology of Food Industry, 2024, 45(21): 368-377. DOI: 10.13386/j.issn1002-0306.2023110270
    [2]CHU Shaoxuan, WANG Xiao, TANG Zheng, ZHANG Zhiyi, DONG Hongjing, GONG Jianquan, ZHENG Zhenjia. Action Mechanism of Nelumbo nucifera Leaf Alkaloids in the Treatment of Hyperuricemia Based on Network Pharmacology and Molecular Docking[J]. Science and Technology of Food Industry, 2024, 45(17): 10-20. DOI: 10.13386/j.issn1002-0306.2023110189
    [3]LI Tingting, GUAN Ya, HONG Zishan, XIE Jing, TIAN Yang. Study on the Anti-obesity Mechanism of Action of Moringa oleifera Lam. Leaves by Network-Based Pharmacology and Molecular Docking Techniques[J]. Science and Technology of Food Industry, 2023, 44(15): 34-45. DOI: 10.13386/j.issn1002-0306.2022090318
    [4]YANG Juan, DOU Jiahong, SUN Yuelong, WANG Xiaoying, ZHOU Weiwei, ZHANG Guobin, LIU Hongxin, YANG Peilong, LI Xiumei. Molecular Mechanism of Phedimus aizoon (Linnaeus)'t Hart. on Anti-inflammatory Effect Based on Network Pharmacology and Molecular Docking and Experiment Research[J]. Science and Technology of Food Industry, 2023, 44(4): 12-21. DOI: 10.13386/j.issn1002-0306.2022050178
    [5]RUAN Shiyang, CHEN Hui, ZENG Fanli, LIAO Shanggao, LUO Xirong. Study on the Mechanism of Mulberry Twig Improving Hyperuricemia Based on Network Pharmacology and Molecular Docking[J]. Science and Technology of Food Industry, 2022, 43(19): 22-30. DOI: 10.13386/j.issn1002-0306.2021120340
    [6]XU Zhaohui, ZOU Yuan, CHEN Ying, LIANG Biao, ZHAO Qing. Mechanism of Cistanches Herba in Treatment of Parkinson’s Disease Based on Network Pharmacology and Molecular Docking[J]. Science and Technology of Food Industry, 2022, 43(9): 13-22. DOI: 10.13386/j.issn1002-0306.2021100009
    [7]SUN Yajia, SUN Jiuxu, HOU Sihan, YAN Mengyun, PEI Lingpeng. Mechanism of Aralia echinocaulis in Treatment of Osteoporosis Based on Network Pharmacology and Molecular Docking[J]. Science and Technology of Food Industry, 2022, 43(8): 11-21. DOI: 10.13386/j.issn1002-0306.2021100014
    [8]SU Yao, WANG Lan, CHANG Xiangna, GONG Pin, YANG Wenjuan, CUI Dandan. Mechanism of Gynostemma pentaphyllum on Prevention and Treatment of Obesity Based on Network Pharmacology and Molecular Docking Technology[J]. Science and Technology of Food Industry, 2022, 43(4): 12-23. DOI: 10.13386/j.issn1002-0306.2021070083
    [9]ZHAO Zhiheng, BI Jinghui, YE Shijie, HUANG Yongkang, MIN Ting, WANG Hongxun, WANG Limei. Mechanism of Astragalus-Ligustrum lucidum in the Treatment of Immunodeficiency Diseases Based on Network Pharmacology and Molecular Docking[J]. Science and Technology of Food Industry, 2022, 43(3): 374-383. DOI: 10.13386/j.issn1002-0306.2021060024
    [10]Yazhi WANG, Jianyong ZHANG, Cancan DUAN. Mechanism of Relieving Alcohol and Protecting Liver of Yigancao Herbal Tea Based on Network Pharmacology and Molecular Docking Technology[J]. Science and Technology of Food Industry, 2021, 42(8): 8-18. DOI: 10.13386/j.issn1002-0306.2020070092

Catalog

    Article Metrics

    Article views (127) PDF downloads (3) Cited by()

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return