Research Progress on Extraction, Separation and Purification Methods, Structural Characterization and Biological Activity of Natural Polysaccharide-Polyphenol Conjugates

REN Yimeng; GAO Yuan; KONG Shuhua; ZHAO Jinwen; REN Dandan; MA Yichao; LIU Shu; HE Yunhai; WANG Qiukuan

doi:10.13386/j.issn1002-0306.2024060022

Volume 46 Issue 10

May 2025

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Science and Technology of Food Industry > 2025 > 46(10): 400-407. > DOI: 10.13386/j.issn1002-0306.2024060022

REN Yimeng, GAO Yuan, KONG Shuhua, et al. Research Progress on Extraction, Separation and Purification Methods, Structural Characterization and Biological Activity of Natural Polysaccharide-Polyphenol Conjugates[J]. Science and Technology of Food Industry, 2025, 46(10): 400−407. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2024060022.

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Research Progress on Extraction, Separation and Purification Methods, Structural Characterization and Biological Activity of Natural Polysaccharide-Polyphenol Conjugates

REN Yimeng^1,,
GAO Yuan¹,
KONG Shuhua¹,
ZHAO Jinwen¹,
REN Dandan^{1, 2, 3, ,},
MA Yichao^{1, 2, 3, ,},
LIU Shu^{1, 2, 3},
HE Yunhai^{1, 2, 3},
WANG Qiukuan^{1, 2, 3}

1.
College of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China
2.
Liaoning Provincial Key Laboratory of Aquatic Products Processing and Comprehensive Utilization, Dalian 116023, China
3.
National Seaweed Processing Technology Research and Development Branch Center, Dalian 116023, China

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Received Date: June 05, 2024
Available Online: March 17, 2025

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Abstract

Abstract

Natural polysaccharide-polyphenol conjugates are compounds formed by the coupling of polysaccharides and polyphenols through chemical or biochemical reactions, which have better biological activities than a single polysaccharide or polyphenol, including anti-inflammatory, antioxidant, anticoagulation, radiation protection, anti-platelet, hypoglycemic activity, etc. So they have broad application prospects in the fields of food, medicine, etc., and have become a current research hotspot. Different extraction, separation and purification methods not only have an impact on the extraction rate of natural polysaccharide-polyphenol conjugates, but also will affect the content of their composition, thereby affecting their biological activity. Due to the complex structure of natural polysaccharide-polyphenol conjugates, its structure and interaction mechanism have not yet been clearly analyzed. The research progress on the extraction, separation, purification, structural characterization, and biological activities of natural polysaccharide-polyphenol conjugates is reviewed in this paper, in order to provide new resources for the development of subsequent functional foods and theoretical references for the application of polysaccharide-polyphenol conjugates in the fields of functional food and cosmetics.

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