Citation: | LIU Yu, ZHANG Xinxin, WANG Rui, et al. Inverse Virtual Screening, Recombinant Expression, and Activity Characterization of Purine Degrading Enzymes[J]. Science and Technology of Food Industry, 2025, 46(5): 145−152. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2024030464. |
[1] |
BORTOLOTTI M, POLITO L, BATTELLI M G, et al. Xanthine oxidoreductase:One enzyme for multiple physiological tasks[J]. Redox Biology,2021,41:101882. doi: 10.1016/j.redox.2021.101882
|
[2] |
郑敏. 猪肉嘌呤含量表型变异及其遗传基础研究[D]. 南昌:江西农业大学, 2017. [ZHENG M. Phenotypic variation and genetic basis of purine content in pork[D]. Nanchang:Jiangxi Agricultural University, 2017.]
ZHENG M. Phenotypic variation and genetic basis of purine content in pork[D]. Nanchang: Jiangxi Agricultural University, 2017.
|
[3] |
于婷婷, 程翅, 喻田. 尿酸肠道代谢的研究现状[J]. 中国临床药理学杂志,2021,37(21):2978−2984. [YU T T, CHENG C, YU T. Research status of uric acid intestinal metabolism[J]. The Chinese of Clinical Pharmacology,2021,37(21):2978−2984.]
YU T T, CHENG C, YU T. Research status of uric acid intestinal metabolism[J]. The Chinese of Clinical Pharmacology, 2021, 37(21): 2978−2984.
|
[4] |
DU F J, HUANG Y Q, HAN R F, et al. Prevalence and trends of hyperuricemia among adults over 40 years old in an economically developed region of China from 2017 to 2020[J]. Journal of Public Health,2022,32(1):43−51.
|
[5] |
中国民族卫生协会重症代谢疾病分会. 中国高尿酸血症相关疾病诊疗多学科专家共识(2023年版)[J]. 中国实用内科杂志,2023,6(43):461−480. [Chinese National Health Association of Severe Metabolic Diseases Branch. Chinese multidisciplinary expert consensus on the diagnosis and treatment of hyperuricemia-related diseases (2023)[J]. Chinese Journal of Practical Internal Medicine,2023,6(43):461−480.]
Chinese National Health Association of Severe Metabolic Diseases Branch. Chinese multidisciplinary expert consensus on the diagnosis and treatment of hyperuricemia-related diseases (2023)[J]. Chinese Journal of Practical Internal Medicine, 2023, 6(43): 461−480.
|
[6] |
LU J, SUN W Y, CUI L L, et al. Across-sectional study on uric acid levels among Chinese adolescents[J]. Pediatric Nephrology,2020,35:441−446. doi: 10.1007/s00467-019-04357-w
|
[7] |
SHA W Q, HOU C L, YUAN E, et al. Different processed milk with residual xanthine oxidase activity and risk of increasing serum uric acid level[J]. Food Bioscience,2021,40:100892. doi: 10.1016/j.fbio.2021.100892
|
[8] |
CHOI H K, ATKINSON K, KARLSON E W, et al. Purine-rich foods, dairy and protein intake, and the risk of gout in men[J]. The New England Journal of Medicine,2004,350(11):1093−1103. doi: 10.1056/NEJMoa035700
|
[9] |
WANG F J, SUN L, ZONG G, et al. Associations of amino acid and acylcarnitine profiles with incident hyperuricemia in middle-aged and older Chinese individuals[J]. Arthritis Care & Rearch,2020,72(9):1305−1314.
|
[10] |
CHEN D D, LI Q X, WU J C. Efficient removal of purine compounds from solutions via biomass carbons derived from pomelo peel[J]. Journal of Bioscience and Bioengineering,2023,136(5):383−390. doi: 10.1016/j.jbiosc.2023.09.002
|
[11] |
WANG X L, YANG S J, LU J, et al. Screening and application of purine degrading Limosilactobacillus fermentum LF-1 from Huangjiu fermentation broth[J]. Journal of the Science of Food and Agriculture,2023,103(15):7921−7931. doi: 10.1002/jsfa.12881
|
[12] |
谢微. 适合痛风病人食用的低嘌呤脱脂豆腐粉的研制[D]. 大庆:黑龙江八一农垦大学, 2012. [XIE W. Development of low purine defatted tofu powder suitable for gout patients[D]. Daqing:Heilongjiang Bayi Agricultural University, 2012.]
XIE W. Development of low purine defatted tofu powder suitable for gout patients[D]. Daqing: Heilongjiang Bayi Agricultural University, 2012.
|
[13] |
李慧慧. 低嘌呤豆浆及其速溶粉的研究[D]. 贵阳:贵州大学, 2016. [LI H H. Study on low purine soybean milk and its instant powder[D]. Guiyang:Guizhou University, 2016.]
LI H H. Study on low purine soybean milk and its instant powder[D]. Guiyang: Guizhou University, 2016.
|
[14] |
潘婷婷, 韦智, 李佳钰, 等. 浸泡时间对豆浆品质的影响及相关性分析[J]. 食品工业科技,2024,45(9):45−53. [PAN T T, WEI Z, LI J Y, et al. The effect of soaking time on the quality of soybean milk and its correlation analysis[J]. Technology of Food Industry,2024,45(9):45−53.]
PAN T T, WEI Z, LI J Y, et al. The effect of soaking time on the quality of soybean milk and its correlation analysis[J]. Technology of Food Industry, 2024, 45(9): 45−53.
|
[15] |
JANKOWSKA D A, FAULWASSER K, TRAUTWEIN-SCHULT A, et al. Arxula adeninivorans recombinant adenine deaminase and its application in the production of food with low purine content[J]. Journal of Applied Microbiology,2013,115(5):1134−1146. doi: 10.1111/jam.12317
|
[16] |
TRAUTWEIN-SCHULT A, JANKOWSKA D, CORDES A, et al. Arxula adeninivorans recombinant guanine deaminase and its application in the production of food with low purine content[J]. Journal of Molecular Microbiology and Biotechnology,2014,24(2):67−81.
|
[17] |
JANKOWSKA D A, TRAUTWEIN-SCHULT A, CORDES A, et al. Arxula adeninivorans xanthine oxidoreductase and its application in the production of food with low purine content[J]. Journal of Applied Microbiology,2013,115(3):796−807. doi: 10.1111/jam.12284
|
[18] |
LIU X F, OUYANG S S, YU B, et al. PharmMapper Server:A web server for potential drug target identification via pharmacophore mapping approach[J]. Nucleic Acids Research,2010,38:W609−W614. doi: 10.1093/nar/gkq300
|
[19] |
WANG X, PAN C X, GONG J Y, et al. Enhancing the enrichment of pharmacophore-based target prediction for the polypharmacological profiles of drugs[J]. Journal of Chemical Information and Modeling,2016,56(6):1175−1183. doi: 10.1021/acs.jcim.5b00690
|
[20] |
WANG X, SHEN Y H, WANG S W, et al. PharmMapper 2017 update:A web server for potential drug target identification with a comprehensive target pharmacophore database[J]. Nucleic Acids Research,2017,45(W1):W356−W360. doi: 10.1093/nar/gkx374
|
[21] |
EBERHARDT J, SANTOS-MARTINS D, TILLACK A F, et al. AutoDock Vina 1.2. 0:New docking methods, expanded force field, and python bindings[J]. Journal of Chemical Information and Modeling,2021,61(8):3891−3898. doi: 10.1021/acs.jcim.1c00203
|
[22] |
TROTT O, OLSON A J. AutoDock Vina:Improving the speed and accuracy of docking with a new scoring function, efficient optimization and multithreading[J]. Journal of Computational Chemistry,2010,31(2):455−461. doi: 10.1002/jcc.21334
|
[23] |
曲欣. 水产品中嘌呤含量分布及其在贮藏加工中变化规律的研究[D]. 青岛:中国海洋大学, 2013. [QU X. Study on the distribution of purine content in aquatic products and its variation during storage and processing[D]. Qingdao:Ocean University of China, 2013.]
QU X. Study on the distribution of purine content in aquatic products and its variation during storage and processing[D]. Qingdao: Ocean University of China, 2013.
|
[24] |
SHAMSOL AZMAN A N S, TAN J J, ABDULLAH M N H, et al. Network pharmacology and molecular docking analysis of active compounds in Tualang honey against atherosclerosis[J]. Foods,2023,12(9):1779. doi: 10.3390/foods12091779
|
[25] |
王烨. A型H1N1流感病毒神经氨酸酶天然产物抑制剂的计算机模拟研究[D]. 长春:吉林大学, 2012. [WANG Y. Computer simulation of natural product inhibitors of neuraminidase of influenza A H1N1 virus[D]. Changchun:Jilin University, 2012.]
WANG Y. Computer simulation of natural product inhibitors of neuraminidase of influenza A H1N1 virus[D]. Changchun: Jilin University, 2012.
|
[26] |
PORTER T N, LI Y C, RAUSHEL F M. Mechanism of the dihydroorotase reaction[J]. Biochemistry,2004,43:16285−16292. doi: 10.1021/bi048308g
|
[27] |
LI N, CUI R, ZHANG F, et al. A novel enzyme from Rhodotorula mucilaginosa aldolase:Isolation, identification and degradation for patulin in apple juice[J]. Process Biochemistry,2022,116:148−156. doi: 10.1016/j.procbio.2022.03.001
|
[28] |
ZHOU L, LIU W, TEREFE N S. The inactivation kinetics of soluble and membrane-bound polyphenol oxidase in pear during thermal and high-pressure processing[J]. Food and Bioprocess Technology,2018,11(5):1039−1049. doi: 10.1007/s11947-018-2070-0
|
[29] |
TIWARI K, KUMAR R, DUBEY V K. Biochemical characterization of dihydroorotase of Leishmania donovani:Understanding pyrimidine metabolism through its inhibition[J]. Biochimie,2016,131:45−53. doi: 10.1016/j.biochi.2016.09.009
|
[30] |
TRUONG L, HEVENER K E, RICE A J, et al. High-level expression, purification, and characterization of Staphylococcus aureus dihydroorotase (PyrC) as a cleavable His-SUMO fusion[J]. Protein Expression and Purification,2013,88(1):98−106. doi: 10.1016/j.pep.2012.11.018
|
[31] |
陆钰. 褐藻胶裂解酶的高效表达及酶学性质分析[D]. 无锡:江南大学, 2022. [LU Y. High-efficiency expression and enzymatic properties analysis of alginate lyase[D]. Wuxi:Jiangnan University, 2022.]
LU Y. High-efficiency expression and enzymatic properties analysis of alginate lyase[D]. Wuxi: Jiangnan University, 2022.
|
[32] |
王成华, 邢新会. 黄嘌呤氧化酶的研究进展及其发展前景[J]. 广西科学,2017,24(1):15−24. [WANG C H, XING X H. Research progress and development prospect of xanthine oxidase[J]. Guangxi Sciences,2017,24(1):15−24.]
WANG C H, XING X H. Research progress and development prospect of xanthine oxidase[J]. Guangxi Sciences, 2017, 24(1): 15−24.
|
[33] |
SHI P, ZHANG R, LIU C X, et al. Computer-assisted in vitro reconstitution of purine degradation pathway to lower the purine content in food[J]. Journal of the Science of Food and Agriculture,2022,102(15):6787−7413. doi: 10.1002/jsfa.11289
|
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