Citation: | SHI Changbo, XU Shuo, ZHAO Juyang, et al. Research Progress on the Composition, Preparation and Promotion of Bioactive Substances Bio-utilization of Self-microemulsion Systems in Food[J]. Science and Technology of Food Industry, 2024, 45(17): 426−435. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2023090291. |
[1] |
常雨, 郑逸梅, 罗碧英, 等. 食品级共价复合物在递送生物活性物质方面的研究进展[J]. 食品工业科技,2022,43(13):389−399. [CHANG Yu, ZHENG Yimei, LUO Biying, et al. Research progress of food-grade covalent complexes for delivery of bioactive substances[J]. Science and Technology of Food Industry,2022,43(13):389−399.]
CHANG Yu, ZHENG Yimei, LUO Biying, et al. Research progress of food-grade covalent complexes for delivery of bioactive substances[J]. Science and Technology of Food Industry, 2022, 43(13): 389−399.
|
[2] |
SANTOS D I, SARAIVA J, VICENTE A A, et al. Methods for determining bioavailability and bioaccessibility of bioactive compounds and nutrients[J]. Innovative Thermal and Non-Thermal Processing, Bioaccessibility and Bioavailability of Nutrients and Bioactive Compounds, 2019:23−54.
|
[3] |
陈雨露, 孙婉秋, 高彦祥, 等. 食品运载体系提高酚类物质生物利用度的研究进展[J]. 食品科学,2020,41(5):323−330. [CHEN Yulu, SUN Wanqiu, GAO Yanxiang, et al. Research progress of food delivery system to improve the bioavailability of phenolic substances[J]. Food Science,2020,41(5):323−330.] doi: 10.7506/spkx1002-6630-20190228-225
CHEN Yulu, SUN Wanqiu, GAO Yanxiang, et al. Research progress of food delivery system to improve the bioavailability of phenolic substances[J]. Food Science, 2020, 41(5): 323−330. doi: 10.7506/spkx1002-6630-20190228-225
|
[4] |
TING Y, JIANG Y, HO C T, et al. Common delivery systems for enhancing in vivo bioavailability and biological efficacy of nutraceuticals[J]. Journal of Functional Foods,2014,7:112−128. doi: 10.1016/j.jff.2013.12.010
|
[5] |
WIGHTMAN E L, REAY J L, HASKELL C F, et al. Effects of resveratrol alone or in combination with piperine on cerebral blood flow parameters and cognitive performance in human subjects:A randomised, double-blind, placebo-controlled, cross-over investigation[J]. British Journal of Nutrition,2014,112(2):203−213. doi: 10.1017/S0007114514000737
|
[6] |
柳欢. 基于共轭亚油酸的脂质载体构建及应用[D]. 无锡:江南大学, 2022. [LIU Huan. Construction and application of conjugated linoleic acid based lipid carrier[D]. Wuxi:Jiangnan University, 2022.]
LIU Huan. Construction and application of conjugated linoleic acid based lipid carrier[D]. Wuxi: Jiangnan University, 2022.
|
[7] |
DHAVAL M, VAGHELA P, PATEL K, et al. Lipid-based emulsion drug delivery systems-a comprehensive review[J]. Drug Deliv Transl Res,2022,12(7):1616−1639. doi: 10.1007/s13346-021-01071-9
|
[8] |
KHAN A W, KOTTA S, ANSARI S H, et al. Potentials and challenges in self-nanoemulsifying drug delivery systems[J]. Expert Opinion on Drug Delivery,2012,9(10):1305−1317. doi: 10.1517/17425247.2012.719870
|
[9] |
MAHMOUD E A, BENDAS E R, MOHAMED M I. Preparation and evaluation of self-nanoemulsifying tablets of carvedilol[J]. Aaps Pharmscitech,2009,10(1):183. doi: 10.1208/s12249-009-9192-7
|
[10] |
CAO M, ZHAN M, WANG Z, et al. Development of an orally bioavailable isoliquiritigenin self-nanoemulsifying drug delivery system to effectively treat ovalbumin-induced asthma[J]. Int J Nanomedicine,2020,15:8945−8961. doi: 10.2147/IJN.S269982
|
[11] |
JIANG F, WU G, LI W, et al. Preparation and protective effects of 1, 8-cineole-loaded self-microemulsifying drug delivery system on lipopolysaccharide-induced endothelial injury in mice[J]. European Journal of Pharmaceutical Sciences,2019,127:14−23. doi: 10.1016/j.ejps.2018.10.012
|
[12] |
SANDER C, HOLM P. Porous magnesium aluminometasilicate tablets as carrier of a cyclosporine self-emulsifying formulation[J]. AAPS PharmSciTech,2009,10:1388−1395. doi: 10.1208/s12249-009-9340-0
|
[13] |
沈熊, 吴伟. 自乳化和自微乳化释药系统[J]. 复旦学报:医学版,2003,30(2):180−183. [SHEN Xiong, WU Wei. Self-emulsifying and self-microemulsifying drug release systems[J]. Fudan Journal:Medical Edition,2003,30(2):180−183.]
SHEN Xiong, WU Wei. Self-emulsifying and self-microemulsifying drug release systems[J]. Fudan Journal: Medical Edition, 2003, 30(2): 180−183.
|
[14] |
张楠, 周宏兵, 全东琴. 自微乳释药系统提高药物生物利用度的机理与应用[J]. 中国医药生物技术,2009,4(1):47−50. [ZHANG Nan, ZHOU Hongbing, QUAN Dongqin. Mechanism and application of self-emulsion drug delivery system to improve drug bioavailability[J]. Chinese Journal of Pharmaceutical Biotechnology,2009,4(1):47−50.] doi: 10.3969/j.issn.1673-713X.2009.01.012
ZHANG Nan, ZHOU Hongbing, QUAN Dongqin. Mechanism and application of self-emulsion drug delivery system to improve drug bioavailability[J]. Chinese Journal of Pharmaceutical Biotechnology, 2009, 4(1): 47−50. doi: 10.3969/j.issn.1673-713X.2009.01.012
|
[15] |
仲粒, 李小芳, 刘罗娜, 等. 自微乳技术在中药制剂中的应用及其固化研究进展[J]. 中药与临床,2019,10(Z2):53−58,64. [ZHONG Mi, LI Xiaofang, LIU Lona, et al. Application of self-microemulsion technology in traditional Chinese medicine preparations and research progress of curing[J]. Chinese Medicine and Clinic,2019,10(Z2):53−58,64.]
ZHONG Mi, LI Xiaofang, LIU Lona, et al. Application of self-microemulsion technology in traditional Chinese medicine preparations and research progress of curing[J]. Chinese Medicine and Clinic, 2019, 10(Z2): 53−58,64.
|
[16] |
YANG F, FU C, LÜ L, et al. Self-microemulsifying delivery system of WPI-Dai nanocomplex mixed with nonionic surfactant and its superiority in delivering daidzein[J]. Food Hydrocolloids,2020,108:105952. doi: 10.1016/j.foodhyd.2020.105952
|
[17] |
马薇. PLH自微乳给药系统及其大鼠体内药动学评价[D]. 广州:广东药科大学, 2016. [MA Wei. PLH self-microemulsion drug delivery system and its pharmacokinetic evaluation in rats[D]. Guangzhou:Guangdong Pharmaceutical University, 2016.]
MA Wei. PLH self-microemulsion drug delivery system and its pharmacokinetic evaluation in rats[D]. Guangzhou: Guangdong Pharmaceutical University, 2016.
|
[18] |
TRUONG D H, TRAN T H, RAMASAMY T, et al. Development of solid self-emulsifying formulation for improving the oral bioavailability of erlotinib[J]. AAPS Pharm Sci Tech,2016,17(2):466−473. doi: 10.1208/s12249-015-0370-5
|
[19] |
张娜, 康虞玲, 刘智勤, 等. 自微乳化药物传递系统的应用与进展[J]. 中国医院药学杂志,2010,30(11):960−962. [ZHANG Na, KANG Yuling, LIU Zhiqin, et al. Application and progress of self-microemulsification drug delivery system[J]. Chinese Journal of Hospital Pharmacy,2010,30(11):960−962.]
ZHANG Na, KANG Yuling, LIU Zhiqin, et al. Application and progress of self-microemulsification drug delivery system[J]. Chinese Journal of Hospital Pharmacy, 2010, 30(11): 960−962.
|
[20] |
梅兴国. 维生素K2固体自乳化制剂的处方优化[J]. 湖北科技学院学报:医学版,2020,34(5):381−385,364. [MEI Xingguo. Formulation optimization of vitamin K2 solid self-emulsifying preparation[J]. Journal of Hubei University of Science and Technology:Medical Edition,2020,34(5):381−385,364.]
MEI Xingguo. Formulation optimization of vitamin K2 solid self-emulsifying preparation[J]. Journal of Hubei University of Science and Technology: Medical Edition, 2020, 34(5): 381−385,364.
|
[21] |
李学艳, 王君文, 易金玉, 等. 含虾青素的雨生红球藻粉自微乳的制备及体外评价[J]. 上海海洋大学学报,2021,30(5):940−949. [LI Xueyan, WANG Junwen, YI Jinyu, et al. Preparation and in vitro evaluation of astaxanthin self-microemulsion of Rhodococcus pluvialis powder[J]. Journal of Shanghai Ocean University,2021,30(5):940−949.] doi: 10.12024/jsou.20200703109
LI Xueyan, WANG Junwen, YI Jinyu, et al. Preparation and in vitro evaluation of astaxanthin self-microemulsion of Rhodococcus pluvialis powder[J]. Journal of Shanghai Ocean University, 2021, 30(5): 940−949. doi: 10.12024/jsou.20200703109
|
[22] |
ČERPNJAK K, ZVONAR A, GAŠPERLIN M, et al. Lipid-based systems as promising approach for enhancing the bioavailability of poorly water-soluble drugs[J]. Acta pharmaceutica,2013,63(4):427−445. doi: 10.2478/acph-2013-0040
|
[23] |
FENG W, QIN C, CIPOLLA E, et al. Inclusion of medium-chain triglyceride in lipid-based formulation of cannabidiol facilitates micellar solubilization in vitro, but in vivo performance remains superior with pure sesame oil vehicle[J]. Pharmaceutics,2021,13(9):1349. doi: 10.3390/pharmaceutics13091349
|
[24] |
GAO H, JIA H, DONG J, et al. Integrated in silico formulation design of self-emulsifying drug delivery systems[J]. Acta Pharmaceutica Sinica B,2021,11(11):3585−3594. doi: 10.1016/j.apsb.2021.04.017
|
[25] |
JADHAV H, WAGHMARE J, ANNAPURE U. Study on oxidative stability of deep fat fried food in Canola oil blended with medium chain triglyceride[J]. Indian Journal of Chemical Technology (IJCT),2022,29(1):95−98.
|
[26] |
陈倩, 陈晨, 管清香. 葛根总黄酮自微乳化半固体骨架胶囊的制备[C]//全国青年药学工作者最新科研成果交流会,2012,90−96. [CHEN Qian, CHEN Chen, GUAN Qingxiang. Preparation of total Pueraria flavonoids self-microemulsified semi-solid skeleton capsules[C]//National Young Pharmaceutical Workers Latest Scientific Research Achievements Exchange Meeting,2012,90−96.]
CHEN Qian, CHEN Chen, GUAN Qingxiang. Preparation of total Pueraria flavonoids self-microemulsified semi-solid skeleton capsules[C]//National Young Pharmaceutical Workers Latest Scientific Research Achievements Exchange Meeting, 2012, 90−96.
|
[27] |
GURRAM A K, DESHPANDE P B, KAR S S, et al. Role of components in the formation of self-microemulsifying drug delivery systems[J]. Indian Journal of Pharmaceutical Sciences,2015,77(3):249−257. doi: 10.4103/0250-474X.159596
|
[28] |
DOKANIA S, JOSHI A K. Self-microemulsifying drug delivery system (SMEDDS)-challenges and road ahead[J]. Drug Delivery,2015,22(6):675−90. doi: 10.3109/10717544.2014.896058
|
[29] |
ITA K. Transdermal drug delivery:Concepts and application[M]. Academic Press, 2020.
|
[30] |
DHRITLAHRE R K, RUCHIKA, PADWAD Y, et al. Self-emulsifying formulations to augment therapeutic efficacy of nutraceuticals:From concepts to clinic[J]. Trends in Food Science & Technology,2021,115:347−365.
|
[31] |
WARISNOICHAROEN W, LANSLEY A B, LAWRENCE M J. Toxicological evaluation of mixtures of nonionic surfactants, alone and in combination with oil[J]. Journal of Pharmaceutical Sciences,2003,92(4):859−868. doi: 10.1002/jps.10335
|
[32] |
LI P, GHOSH A, WAGNER R F, et al. Effect of combined use of nonionic surfactant on formation of oil-in-water microemulsions[J]. International Journal of Pharmaceutics,2005,288(1):27−34. doi: 10.1016/j.ijpharm.2004.08.024
|
[33] |
KIM D W, KWON M S, YOUSAF A M, et al. Comparison of a solid SMEDDS and solid dispersion for enhanced stability and bioavailability of clopidogrel napadisilate[J]. Carbohydrate Polymers,2014,114:365−374. doi: 10.1016/j.carbpol.2014.08.034
|
[34] |
卢文彪. 连香方自微乳化给药系统的制备与评价[D]. 广州:广州中医药大学, 2008. [LU Wenbiao. Preparation and evaluation of self-microemulsification drug delivery system of Lianxiang prescription[D]. Guangzhou:Guangzhou University of Traditional Chinese Medicine, 2008.]
LU Wenbiao. Preparation and evaluation of self-microemulsification drug delivery system of Lianxiang prescription[D]. Guangzhou: Guangzhou University of Traditional Chinese Medicine, 2008.
|
[35] |
杨丽雄. 自微乳化释药系统在药物制剂中的应用[J]. 海峡药学,2011,23(12):5−7. [YANG Lixiong. Application of self-microemulsification drug release system in pharmaceutical preparations[J]. Straits Pharmacy,2011,23(12):5−7.] doi: 10.3969/j.issn.1006-3765.2011.12.002
YANG Lixiong. Application of self-microemulsification drug release system in pharmaceutical preparations[J]. Straits Pharmacy, 2011, 23(12): 5−7. doi: 10.3969/j.issn.1006-3765.2011.12.002
|
[36] |
凡小燕. 橙皮苷自微乳的制备与评价[D]. 合肥:安徽医科大学, 2011. [FAN Xiaoyan. Preparation and evaluation of hesperidin self-microemulsion[D]. Hefei:Anhui Medical University, 2011.]
FAN Xiaoyan. Preparation and evaluation of hesperidin self-microemulsion[D]. Hefei: Anhui Medical University, 2011.
|
[37] |
CHEN H, YANG F, LÜ L, et al. Interaction among protein, daidzein and surfactants in the WPI-based daidzein self-microemulsifying delivery system[J]. Food Chemistry,2020,332:127461. doi: 10.1016/j.foodchem.2020.127461
|
[38] |
杨志欣, 张蕾, 王鑫, 等. 自乳化药物递送系统研究概述[J]. 中文科技资料目录-中草药,2019,42(3):563−569. [YANG Zhixin, ZHANG Lei, WANG Xin, et al. Overview of self-emulsifying drug delivery system[J]. Chinese Science and Technology Bibliography-Chinese Herbal Medicine,2019,42(3):563−569.]
YANG Zhixin, ZHANG Lei, WANG Xin, et al. Overview of self-emulsifying drug delivery system[J]. Chinese Science and Technology Bibliography-Chinese Herbal Medicine, 2019, 42(3): 563−569.
|
[39] |
CHEN Y, LI G, WU X, et al. Self-microemulsifying drug delivery system (SMEDDS) of vinpocetine:Formulation development and in vivo assessment[J]. Biological & Pharmaceutical Bulletin,2008,31(1):118−125.
|
[40] |
黎鹏, 程永婷, 马峰, 等. 乳香没药精油自微乳的制备与抗炎镇痛作用评价[J]. 药物评价研究,2023,46(4):795−802. [LI Peng, CHENG Yongting, MA Feng, et al. Preparation of frankincense myrrh essential oil self-microemulsion and evaluation of anti-inflammatory and analgesic effects[J]. Drug Evaluation Research,2023,46(4):795−802.]
LI Peng, CHENG Yongting, MA Feng, et al. Preparation of frankincense myrrh essential oil self-microemulsion and evaluation of anti-inflammatory and analgesic effects[J]. Drug Evaluation Research, 2023, 46(4): 795−802.
|
[41] |
SANEJA A. Recent advances in self-emulsifying drug-delivery systems for oral delivery of cancer chemotherapeutics[M]. 2016.
|
[42] |
毛昕宇. 虾青素微纳米载体的制备与评价[D]. 南京:东南大学, 2019. [MAO Xinyu. Preparation and evaluation of astaxanthin micro nano carriers[D]. Nanjing:Southeast University, 2019.]
MAO Xinyu. Preparation and evaluation of astaxanthin micro nano carriers[D]. Nanjing: Southeast University, 2019.
|
[43] |
WANG Y, CHEN L, ADU-FRIMPONG M, et al. Preparation, in vivo and in vitro evaluation, and pharmacodynamic study of DMY-loaded self-microemulsifying drug delivery system[J]. European Journal of Lipid Science and Technology,2021,123(6):2000369. doi: 10.1002/ejlt.202000369
|
[44] |
DHOLAKIYA A, DUDHAT K, PATEL J, et al. An integrated QbD based approach of SMEDDS and liquisolid compacts to simultaneously improve the solubility and processability of hydrochlorothiazide[J]. Journal of Drug Delivery Science and Technology, 2020:102162.
|
[45] |
VISETVICHAPORN V, KIM K H, JUNG K, et al. Formulation of self-microemulsifying drug delivery system (SMEDDS) by D-optimal mixture design to enhance the oral bioavailability of a new cathepsin K inhibitor (HL235)[J]. International Journal of Pharmaceutics,2020,573:118772. doi: 10.1016/j.ijpharm.2019.118772
|
[46] |
HUANG J, WANG Q, SUN R, et al. A novel solid self-emulsifying delivery system (SEDS) for the encapsulation of linseed oil and quercetin:Preparation and evaluation[J]. Journal of Food Engineering,2018,226(JUN.):22−30.
|
[47] |
张建, 叶珍珍, 崔升淼. 固体自乳化新剂型的研究进展[J]. 中南药学,2011,9(5):358−362. [ZHANG Jian, YE Zhenzhen, CUI Shengmiao. Research progress on new solid self-emulsifying formulations[J]. Zhongnan Pharmacy,2011,9(5):358−362.] doi: 10.3969/j.issn.1672-2981.2011.05.011
ZHANG Jian, YE Zhenzhen, CUI Shengmiao. Research progress on new solid self-emulsifying formulations[J]. Zhongnan Pharmacy, 2011, 9(5): 358−362. doi: 10.3969/j.issn.1672-2981.2011.05.011
|
[48] |
POUTON C W. Formulation of poorly water-soluble drugs for oral administration:Physicochemical and physiological issues and the lipid formulation classification system[J]. European Journal of Pharmaceutical Sciences,2006,29(3-4):278−287. doi: 10.1016/j.ejps.2006.04.016
|
[49] |
黄娟, 岳晶晶, 冯璇, 等. 二氢杨梅素固体自微乳的制备及表征[J]. 食品科学,2022,43(16):145−152. [HUANG Juan, YUE Jingjing, FENG Xuan, et al. Preparation and characterization of dihydromyricetin solid self-microemulsion[J]. Food Science,2022,43(16):145−152.] doi: 10.7506/spkx1002-6630-20210905-053
HUANG Juan, YUE Jingjing, FENG Xuan, et al. Preparation and characterization of dihydromyricetin solid self-microemulsion[J]. Food Science, 2022, 43(16): 145−152. doi: 10.7506/spkx1002-6630-20210905-053
|
[50] |
TANG B, CHENG G, GU J C, et al. Development of solid self-emulsifying drug delivery systems:Preparation techniques and dosage forms[J]. Drug Discovery Today,2008,13(13-14):606−612. doi: 10.1016/j.drudis.2008.04.006
|
[51] |
马祖兵. 大黄素自微乳—微丸释药体系的构建与评价研究[D]. 成都:成都中医药大学, 2019. [MA Zubing. Construction and evaluation of emodin release system from microemulsion to micropellet[D]. Chengdu:Chengdu University of Traditional Chinese Medicine, 2019.]
MA Zubing. Construction and evaluation of emodin release system from microemulsion to micropellet[D]. Chengdu: Chengdu University of Traditional Chinese Medicine, 2019.
|
[52] |
SELJAK K B, ILIĆ I G, GAŠPERLIN M, et al. Self-microemulsifying tablets prepared by direct compression for improved resveratrol delivery[J]. International Journal of Pharmaceutics,2018,548(1):263−275. doi: 10.1016/j.ijpharm.2018.06.065
|
[53] |
王丽娜, 李校娜, 王树鹏, 等. 中药固体自微乳化给药系统的研究进展[J]. 畜牧与兽医,2019,51(5):135−138. [WANG L N, LI X N, WANG S P, et al. Research progress of solid self-microemulsification drug delivery system of traditional Chinese medicine[J]. Animal Husbandry and Veterinary Medicine,2019,51(5):135−138.]
WANG L N, LI X N, WANG S P, et al. Research progress of solid self-microemulsification drug delivery system of traditional Chinese medicine[J]. Animal Husbandry and Veterinary Medicine, 2019, 51(5): 135−138.
|
[54] |
金可欣, 吕江维, 贲昱文, 等. 固体自微乳药物递送系统的研究进展[J]. 药学研究,2019,42(2):126−129,144. [JIN Kexin, LÜ Jiangwei, BEN Yuwen, et al. Research progress of solid self-microemulsion drug delivery system[J]. Pharmaceutical Research,2019,42(2):126−129,144.]
JIN Kexin, LÜ Jiangwei, BEN Yuwen, et al. Research progress of solid self-microemulsion drug delivery system[J]. Pharmaceutical Research, 2019, 42(2): 126−129,144.
|
[55] |
梅康康, 胡容峰, 罗志红, 等. 球晶技术固体自微乳法制备水飞蓟宾缓释微丸[J]. 中国医院药学杂志,2014,34(21):1826−1831. [MEI Kangkang, HU Rongfeng, LUO Zhihong, et al. Preparation of silybin sustained-release pellets by solid self-emulsion method[J]. Chinese Journal of Hospital Pharmacy,2014,34(21):1826−1831.]
MEI Kangkang, HU Rongfeng, LUO Zhihong, et al. Preparation of silybin sustained-release pellets by solid self-emulsion method[J]. Chinese Journal of Hospital Pharmacy, 2014, 34(21): 1826−1831.
|
[56] |
LLERA-ROJAS V G, DEL REAL L A, MENDOZA-MUÑOZ N, et al. Feasibility of obtaining in situ nanocapsules through modified self-microemulsifying drug delivery systems. A new manufacturing approach for oral route administration[J]. Drug Development and Industrial Pharmacy,2017,43(6):925−931. doi: 10.1080/03639045.2017.1285308
|
[57] |
GUILAN Q, BOYI N, VIKRAMJEET S, et al. Supersaturable solid self-microemulsifying drug delivery system:Precipitation inhibition and bioavailability enhancement[J]. International Journal of Nanomedicine,2017,12:8801−8811. doi: 10.2147/IJN.S149717
|
[58] |
KAMBOJ S, RANA V. Quality-by-design based development of a self-microemulsifying drug delivery system to reduce the effect of food on nelfinavir mesylate[J]. International Journal of Pharmaceutics,2016(501):311−325.
|
[59] |
张莉莉, 李婉菁, 彭锦学, 等. 应用离子液体溶剂体系提取天然虾青素的研究进展[J]. 食品工业科技,2020,41(8):341−346. [ZHANG Lili, LI Wanjing, PENG Jinxue, et al. Research progress of natural astaxanthin extraction by ionic liquid solvent system[J]. Science and Technology of Food Industry,2020,41(8):341−346.]
ZHANG Lili, LI Wanjing, PENG Jinxue, et al. Research progress of natural astaxanthin extraction by ionic liquid solvent system[J]. Science and Technology of Food Industry, 2020, 41(8): 341−346.
|
[60] |
张智衡. 玉米醇溶蛋白基多酚递送体系构建及其消化特性研究[D]. 无锡:江南大学, 2023. [ZHANG Zhiheng. Study on the construction of zein-based polyphenoldelivery systems and their digestion characteristics[D]. Wuxi:Jiangnan University, 2023.]
ZHANG Zhiheng. Study on the construction of zein-based polyphenoldelivery systems and their digestion characteristics[D]. Wuxi: Jiangnan University, 2023.
|
[61] |
HOLM R, PORTER C, EDWARDS G A, et al. Examination of oral absorption and lymphatic transport of halofantrine in a triple-cannulated canine model after administration in self-microemulsifying drug delivery systems (SMEDDS) containing structured triglycerides[J]. European Journal of Pharmaceutical Sciences,2003,20(1):91−97. doi: 10.1016/S0928-0987(03)00174-X
|
[62] |
谭亚男, 尹宗宁. 自微乳化给药系统促进卤泛群经淋巴转运的研究[J]. 食品与药品,2021(4):332−337. [TAN Yanan, YIN Zongning. Study on the promotion of translymphatic transport of halopantrin by self-microemulsification drug delivery system[J]. Food and Drug,2021(4):332−337.] doi: 10.3969/j.issn.1672-979X.2021.04.009
TAN Yanan, YIN Zongning. Study on the promotion of translymphatic transport of halopantrin by self-microemulsification drug delivery system[J]. Food and Drug, 2021(4): 332−337. doi: 10.3969/j.issn.1672-979X.2021.04.009
|
[63] |
梁鑫淼, 王超然, 郭志谋, 等. 一种酸枣仁黄酮磷脂复合物及其制备方法和应用:CN112544972A[P]. 2021. [LIANG Xinmiao, WANG Chaoran, GUO Zhimo, et al. A kind of jujube kernel flavonoid phospholipid complex and its preparation method and application:CN112544972A[P]. 2021.]
LIANG Xinmiao, WANG Chaoran, GUO Zhimo, et al. A kind of jujube kernel flavonoid phospholipid complex and its preparation method and application: CN112544972A[P]. 2021.
|
[64] |
EL-SAYED H S, CHIZZOLA R, RAMADAN A A, et al. Chemical composition and antimicrobial activity of garlic essential oils evaluated in organic solvent, emulsifying, and self-microemulsifying water based delivery systems[J]. Food Chemistry,2017,221(APR.15):196−204.
|
[65] |
ALMASI L, RADI M, AMIRI S. The release rate and antimicrobial activity of calcium-alginate films containing self-microemulsifying Thymus vulgaris essential oil against Escherichia coli and Staphylococcus aureus[J]. Journal of Food Safety,2020,40(5):e12828. doi: 10.1111/jfs.12828
|
[66] |
ALMASI L, RADI M, AMIRI S, et al. Fabrication and characterization of antimicrobial biopolymer films containing essential oil-loaded microemulsions or nanoemulsions[J]. Food Hydrocolloids,2021,117(1):106733.
|
[67] |
胡万超, 唐建国. 大蒜提取物抗白念珠菌作用机制研究进展[J]. 中国感染与化疗杂志,2020,20(2):221−225. [HU Wanchao, TANG Jianguo. Research progress of garlic extracts against Candida albicans[J]. Chinese Journal of Infection and Chemotherapy,2020,20(2):221−225.]
HU Wanchao, TANG Jianguo. Research progress of garlic extracts against Candida albicans[J]. Chinese Journal of Infection and Chemotherapy, 2020, 20(2): 221−225.
|
[68] |
LONG Y, HUANG W, WANG Q, et al. Green synthesis of garlic oil nanoemulsion using ultrasonication technique and its mechanism of antifungal action against Penicillium italicum[J]. Ultrasonics Sonochemistry,2020,64:104970. doi: 10.1016/j.ultsonch.2020.104970
|
[69] |
赵家亮, 李春, 刘宁, 等. 食品级非离子表面活性剂微乳的制备及抗菌性研究[J]. 食品工业,2011(9):92−95. [ZHAO Jialiang, LI Chun, LIU Ning, et al. Preparation and antibacterial activity of food grade non-ionic surfactant microemulsion[J]. Food Industry,2011(9):92−95.]
ZHAO Jialiang, LI Chun, LIU Ning, et al. Preparation and antibacterial activity of food grade non-ionic surfactant microemulsion[J]. Food Industry, 2011(9): 92−95.
|
[70] |
王浩. 丁香油乳化体系的制备及抗菌特性的研究[D]. 无锡:江南大学, 2014. [WANG Hao. Study on preparation and antibacterial properties of clove oil emulsification system[D]. Wuxi:Jiangnan University, 2014.]
WANG Hao. Study on preparation and antibacterial properties of clove oil emulsification system[D]. Wuxi: Jiangnan University, 2014.
|
[71] |
肖小年, 周洁, 易孜成, 等. 大蒜油自微乳的制备及其初步稳定性[J]. 南昌大学学报(理科版),2020,44(1):42−48. [XIAO Xiaonian, ZHOU Jie, YI Zicheng, et al. Preparation and preliminary stability of garlic oil self-microemulsion[J]. Journal of Nanchang University:Science Edition,2020,44(1):42−48.] doi: 10.3969/j.issn.1006-0464.2020.01.008
XIAO Xiaonian, ZHOU Jie, YI Zicheng, et al. Preparation and preliminary stability of garlic oil self-microemulsion[J]. Journal of Nanchang University: Science Edition, 2020, 44(1): 42−48. doi: 10.3969/j.issn.1006-0464.2020.01.008
|
[72] |
肖小年, 盛丹梅, 周洁, 等. 大蒜油自微乳的抑菌作用[J]. 中国食品学报,2021,21(12):73−80. [XIAO Xiaonian, SHENG Danmei, ZHOU Jie, et al. Bacteriostasis of garlic oil self-microemulsion[J]. Chinese Journal of Food Science,2021,21(12):73−80.]
XIAO Xiaonian, SHENG Danmei, ZHOU Jie, et al. Bacteriostasis of garlic oil self-microemulsion[J]. Chinese Journal of Food Science, 2021, 21(12): 73−80.
|
[73] |
李媛媛, 于良晓, 裴海生, 等. 药食同源生物活性物质降脂减重机制研究进展[J]. 食品安全质量检测学报,2022,13(22):7407−7414. [LI Yuanyuan, YU Liangxiao, PEI Haisheng, et al. Research progress on the mechanism of lipid and weight loss of homologous bioactive substances[J]. Journal of Food Safety and Quality Inspection,2022,13(22):7407−7414.] doi: 10.3969/j.issn.2095-0381.2022.22.spaqzljcjs202222032
LI Yuanyuan, YU Liangxiao, PEI Haisheng, et al. Research progress on the mechanism of lipid and weight loss of homologous bioactive substances[J]. Journal of Food Safety and Quality Inspection, 2022, 13(22): 7407−7414. doi: 10.3969/j.issn.2095-0381.2022.22.spaqzljcjs202222032
|
[74] |
杨春红, 潘琳, 唐茜, 等. 辅助降血糖功能的药食同源原料的应用概况[J]. 中药与临床,2022,13(1):103−107, 114. [YANG Chunhong, PAN Lin, TANG Qian, et al. Application of homologous materials of medicine and food to assist hypoglycemic function[J]. Chinese Medicine and Clinic,2022,13(1):103−107, 114.] doi: 10.3969/j.issn.1674-926X.2022.01.023
YANG Chunhong, PAN Lin, TANG Qian, et al. Application of homologous materials of medicine and food to assist hypoglycemic function[J]. Chinese Medicine and Clinic, 2022, 13(1): 103−107, 114. doi: 10.3969/j.issn.1674-926X.2022.01.023
|
[75] |
田翠芳, 张昭寰, 陶倩, 等. 抗生物被膜材料在食品微生物安全领域的应用研究进展[J]. 食品科学,2022,43(11):265−272. [TIAN Cuifang, ZHANG Zhaohuan, TAO Qian, et al. Research progress on application of anti-biofilm materials in food microbial safety[J]. Food Science,2022,43(11):265−272.]
TIAN Cuifang, ZHANG Zhaohuan, TAO Qian, et al. Research progress on application of anti-biofilm materials in food microbial safety[J]. Food Science, 2022, 43(11): 265−272.
|
[76] |
张家旭, 郭玉儿, 王信, 等. 金樱子活性成分, 生物功能及其在食品应用中的研究进展[J]. 食品科技,2023,48(1):98−106. [ZHANG Jiaxu, GUO Yuer, WANG Xin, et al. Research progress of active ingredients, biological functions and application in food[J]. Food Science and Technology,2023,48(1):98−106.]
ZHANG Jiaxu, GUO Yuer, WANG Xin, et al. Research progress of active ingredients, biological functions and application in food[J]. Food Science and Technology, 2023, 48(1): 98−106.
|
[77] |
MOSTAFA D M, EL-ALIM S, KASSEM A A. Nanoemulsions:A new approach for enhancing phytonutrient efficacy[M]//Nanotechnology Applications in Food. Academic Press, 2017:107−127.
|
[78] |
金栋, 胡容峰, 周安, 等. 灵芝孢子油自微乳的制备及其质量评价[J]. 安徽中医药大学学报,2017,36(6):89−92. [JIN Dong, HU Rongfeng, ZHOU An, et al. Preparation and quality evaluation of Ganoderma lucidum spore oil self-microemulsion[J]. Journal of Anhui University of Traditional Chinese Medicine,2017,36(6):89−92.] doi: 10.3969/j.issn.2095-7246.2017.06.024
JIN Dong, HU Rongfeng, ZHOU An, et al. Preparation and quality evaluation of Ganoderma lucidum spore oil self-microemulsion[J]. Journal of Anhui University of Traditional Chinese Medicine, 2017, 36(6): 89−92. doi: 10.3969/j.issn.2095-7246.2017.06.024
|
[79] |
XU Y, WANG Q, FENG Y, et al. Enhanced oral bioavailability of [6]-Gingerol-SMEDDS:Preparation, in vitro and in vivo evaluation[J]. Journal of Functional Foods,2016,27:703−710. doi: 10.1016/j.jff.2016.10.007
|
[80] |
CHEN Y, ZHANG H, YANG J, et al. Improved antioxidant capacity of optimization of a self-microemulsifying drug delivery system for resveratrol[J]. Molecules,2015,20(12):21167−21177. doi: 10.3390/molecules201219750
|
[81] |
LYU Q, CHEN L, LIN S, et al. A designed self-microemulsion delivery system for dihydromyricetin and its dietary intervention effect on high-fat-diet fed mice[J]. Food Chemistry,2022(Oct.1):390.
|
[82] |
CHOU Y C, LI S, HO C T, et al. Preparation and evaluation of self-microemulsifying delivery system containing 5-demethyltangeretin on inhibiting xenograft tumor growth in mice[J]. International Journal of Pharmaceutics,2020,579:119134. doi: 10.1016/j.ijpharm.2020.119134
|
1. |
陈璐瑶,张志刚,邢国良,王捷,姚玉军,吕兆林. 沙棘叶及其醇提冻干粉挥发性物质和关键营养成分分析. 食品工业科技. 2025(08): 272-280 .
![]() | |
2. |
宋娟,康三江,张海燕,曾朝珍,袁晶,慕钰文,苟丽娜. 响应面法优化黑苹果发酵工艺及其抗氧化活性评价. 中国酿造. 2024(11): 159-166 .
![]() |