Citation: | CHEN Hao, YIN Junye, HAO Jianxiong, et al. Research Progress on the Bioactivity and Mechanisms of Jujube Polysaccharides[J]. Science and Technology of Food Industry, 2024, 45(13): 342−351. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2023070276. |
[1] |
朱星宇, 郭东起. 红枣关键功能成分及其生物活性的研究进展[J]. 食品研究与开发,2021,42(8):197−201. [ZHU X Y, GUO D Q. Research progress of key functional components and biological activities of jujube[J]. Food Research and Development,2021,42(8):197−201.] doi: 10.12161/j.issn.1005-6521.2021.08.032
ZHU X Y, GUO D Q. Research progress of key functional components and biological activities of jujube[J]. Food Research and Development, 2021, 42(8): 197−201. doi: 10.12161/j.issn.1005-6521.2021.08.032
|
[2] |
JI X, PENG Q, YUAN Y, et al. Isolation, structures and bioactivities of the polysaccharides from jujube fruit (Ziziphus jujuba Mill.):A review[J]. Food Chemistry,2017,227:349−357. doi: 10.1016/j.foodchem.2017.01.074
|
[3] |
RUAN J, HAN Y, KENNEDY J F, et al. A review on polysaccharides from jujube and their pharmacological activities[J]. Carbohydrate Polymer Technologies and Applications,2022,3:100220. doi: 10.1016/j.carpta.2022.100220
|
[4] |
马宝珠, 刘世军, 李慧, 等. 大枣不同加工部位含糖量测定及脱糖大枣的研究思路[J]. 西部中医药,2021,34(4):31−35. [MA B Z, LIU S J, LI H, et al. Determination of sugar content in different processing parts of Chinese jujube and research ideas of desugared jujube[J]. Western Chinese Medicine,2021,34(4):31−35.]
MA B Z, LIU S J, LI H, et al. Determination of sugar content in different processing parts of Chinese jujube and research ideas of desugared jujube[J]. Western Chinese Medicine, 2021, 34(4): 31−35.
|
[5] |
张耀雷, 黄立新, 张彩虹, 等. 红枣多糖的研究进展[J]. 食品工业科技,2013,34(23):349−353. [ZHANG Y L, HUANG L X, ZHANG C H, et al. Research progress of polysaccharides from red jujube[J]. Science and Technology of Food Industry,2013,34(23):349−353.]
ZHANG Y L, HUANG L X, ZHANG C H, et al. Research progress of polysaccharides from red jujube[J]. Science and Technology of Food Industry, 2013, 34(23): 349−353.
|
[6] |
ZOU X, XIAO J, CHI J, et al. Physicochemical properties and prebiotic activities of polysaccharides from Zizyphus jujube based on different extraction techniques[J]. International Journal of Biological Macromolecules,2022,223(Pt A):663−672.
|
[7] |
JI X, HOU C, YAN Y, et al. Comparison of structural characterization and antioxidant activity of polysaccharides from jujube (Ziziphus jujuba Mill.) fruit[J]. International Journal of Biological Macromolecules,2020,149:1008−1018. doi: 10.1016/j.ijbiomac.2020.02.018
|
[8] |
LIU X X, LIU H M, YAN Y Y, et al. Structural characterization and antioxidant activity of polysaccharides extracted from jujube using subcritical water[J]. LWT-Science and Technology,2020,117:108645.
|
[9] |
ZHAO Z, LI J, WU X, et al. Structures and immunological activities of two pectic polysaccharides from the fruits of Ziziphus jujuba Mill. cv. jinsixiaozao Hort[J]. Food Research International,2006,39(8):917−923. doi: 10.1016/j.foodres.2006.05.006
|
[10] |
符玉霞, 郭欣, 魏亚博, 等. 红枣多糖的硫酸酯化修饰及其结构特性的研究[J]. 食品工业,2022,43(8):33−38. [FU Y X, GUO X, WEI Y B, et al. Study on sulfated modification and structural properties of jujube polysaccharide[J]. Food Industry,2022,43(8):33−38.]
FU Y X, GUO X, WEI Y B, et al. Study on sulfated modification and structural properties of jujube polysaccharide[J]. Food Industry, 2022, 43(8): 33−38.
|
[11] |
FENG R, KOU J, CHEN S, et al. Preparation optimization, characterization, and antioxidant and prebiotic activities of carboxymethylated polysaccharides from jujube[J]. Journal of Food Quality,2021,2021:1−15.
|
[12] |
CAI Y, CHEN P, WU C, et al. Sulfated modification and biological activities of polysaccharides derived from Zizyphus jujuba cv. Jinchangzao[J]. International Journal of Biological Macromolecules,2018,120:1149−1155. doi: 10.1016/j.ijbiomac.2018.08.141
|
[13] |
夏世金, 孙涛, 吴俊珍. 自由基、炎症与衰老[J]. 实用老年医学,2014,28(2):100−103. [XIA S J, SUN T, WU J Z. Free radicals, inflammation and aging[J]. Practical Geriatrics,2014,28(2):100−103.]
XIA S J, SUN T, WU J Z. Free radicals, inflammation and aging[J]. Practical Geriatrics, 2014, 28(2): 100−103.
|
[14] |
GULCIN I. Antioxidants and antioxidant methods:An updated overview[J]. Archives of Toxicology,2020,94(3):651−715. doi: 10.1007/s00204-020-02689-3
|
[15] |
白冰瑶, 付超, 黄茂汐, 等. 红枣多糖的抗氧化活性及体外模拟消化和酵解研究[J]. 塔里木大学学报,2022,34(2):24−34. [BAI B Y, FU C, HUANG M X, et al. Study on antioxidant activity and in vitro simulated digestion and glycolysis of polysaccharides from red jujube[J]. Journal of Tarim University,2022,34(2):24−34.] doi: 10.3969/j.issn.1009-0568.2022.02.004
BAI B Y, FU C, HUANG M X, et al. Study on antioxidant activity and in vitro simulated digestion and glycolysis of polysaccharides from red jujube[J]. Journal of Tarim University, 2022, 34(2): 24−34. doi: 10.3969/j.issn.1009-0568.2022.02.004
|
[16] |
WANG Y, XU Y, MA X, et al. Extraction, purification, characterization and antioxidant activities of polysaccharides from Zizyphus jujuba cv. Linzexiaozao[J]. International Journal of Biological Macromolecules, 2018, 118(Pt B):2138-2148.
|
[17] |
呼凤兰, 胡诗琪. 吕梁红枣多糖的提取及其抗氧化性研究[J]. 北方园艺,2022(22):91−96. [HU F L, HU S Q. Study on extraction and antioxidant activity of polysaccharides from Chinese jujube[J]. Northern Horticulture,2022(22):91−96.]
HU F L, HU S Q. Study on extraction and antioxidant activity of polysaccharides from Chinese jujube[J]. Northern Horticulture, 2022(22): 91−96.
|
[18] |
展锐, 邵金辉. 大枣多糖抗氧化及抗炎活性的研究[J]. 现代食品科技,2017,33(12):38−43. [ZHAN R, SHAO J H. Study on antioxidant and anti-inflammatory activities of polysaccharides from jujube[J]. Modern Food Science and Technology,2017,33(12):38−43.]
ZHAN R, SHAO J H. Study on antioxidant and anti-inflammatory activities of polysaccharides from jujube[J]. Modern Food Science and Technology, 2017, 33(12): 38−43.
|
[19] |
ZHAN R, XIA L, SHAO J, et al. Polysaccharide isolated from Chinese jujube fruit (Zizyphus jujuba cv. Junzao) exerts anti-inflammatory effects through MAPK signaling[J]. Journal of Functional Foods,2018,40:461−470. doi: 10.1016/j.jff.2017.11.026
|
[20] |
LIU Y, ZHANG Y, MEI N, et al. Three acidic polysaccharides derived from sour jujube seeds protect intestinal epithelial barrier function in LPS induced Caco-2 cell inflammation model[J]. Int J Biol Macromol,2023,240:124435. doi: 10.1016/j.ijbiomac.2023.124435
|
[21] |
YANG Y, QIU Z, LI L, et al. Structural characterization and antioxidant activities of one neutral polysaccharide and three acid polysaccharides from Ziziphus jujuba cv. Hamidazao:A comparison[J]. Carbohydrate Polymers,2021,261:117879. doi: 10.1016/j.carbpol.2021.117879
|
[22] |
WANG B. Chemical characterization and ameliorating effect of polysaccharide from Chinese jujube on intestine oxidative injury by ischemia and reperfusion[J]. International Journal of Biological Macromolecules,2011,48(3):386−391. doi: 10.1016/j.ijbiomac.2010.12.005
|
[23] |
SHEN X, TANG Y, YANG R, et al. The protective effect of Zizyphus jujube fruit on carbon tetrachloride-induced hepatic injury in mice by anti-oxidative activities[J]. Journal of Ethnopharmacology,2009,122(3):555−560. doi: 10.1016/j.jep.2009.01.027
|
[24] |
LIU L. Study of jujube polysaccharide on protection from lipid peroxidation damage of cardiac muscle tissue after exercise[P]. Proceedings of the 2016 6th International Conference on Applied Science, Engineering and Technology, 2016.
|
[25] |
LIU C, QIU Z, GU D, et al. A novel anti-inflammatory polysaccharide from blackened jujube:Structural features and protective effect on dextran sulfate sodium-induced colitic mice[J]. Food Chemistry,2023,405(PA):134869.
|
[26] |
高蓓, 初海超, 芦文丽, 等. 1990~2019年中国恶性肿瘤疾病负担变化趋势分析[J]. 中华疾病控制杂志,2022,26(4):430−436,489. [GAO B, CHU H C, LU W L, et al. Trend analysis of malignant tumor disease burden in China from 1990 to 2019[J]. Chinese Journal of Disease Control,2022,26(4):430−436,489.]
GAO B, CHU H C, LU W L, et al. Trend analysis of malignant tumor disease burden in China from 1990 to 2019[J]. Chinese Journal of Disease Control, 2022, 26(4): 430−436,489.
|
[27] |
CAI Y, XUE M, CHEN W, et al. Expenditure of hospital care on cancer in China, from 2011 to 2015[J]. Chinese Journal of Cancer Research,2017,29(3):253−262. doi: 10.21147/j.issn.1000-9604.2017.03.11
|
[28] |
KHAN T, DATE A, CHAWDA H, et al. Polysaccharides as potential anticancer agents-A review of their progress[J]. Carbohydrate Polymers,2019,210:412−428. doi: 10.1016/j.carbpol.2019.01.064
|
[29] |
李晋, 徐尚福, 殷国海, 等. 红枣多糖对人肝癌HepG-2细胞的抑制作用[J]. 贵州医药,2014,38(6):506−508. [LI J, XU S F, YIN G H, et al. Inhibitory effect of jujube polysaccharide on HepG-2 cells of human hepatoma[J]. Guizhou Medicine,2014,38(6):506−508.] doi: 10.3969/j.ISSN.1000-744X.2014.06.007
LI J, XU S F, YIN G H, et al. Inhibitory effect of jujube polysaccharide on HepG-2 cells of human hepatoma[J]. Guizhou Medicine, 2014, 38(6): 506−508. doi: 10.3969/j.ISSN.1000-744X.2014.06.007
|
[30] |
LIANG Q, WANG X, YANG S, et al. Characterization of the antioxidative polysaccharides from Ziziphus jujube cv. Goutouzao and its tumor-inhibitory effects on human colorectal carcinoma LoVo cells via immunocyte activation[J]. Journal of Food Biochemistry,2020,44(11):e13462.
|
[31] |
HUNG C F, HSU B Y, CHANG S C, et al. Antiproliferation of melanoma cells by polysaccharide isolated from Zizyphus jujuba[J]. Nutrition,2012,28(1):98−105. doi: 10.1016/j.nut.2011.05.009
|
[32] |
JI X, HOU C, GAO Y, et al. Metagenomic analysis of gut microbiota modulatory effects of jujube (Ziziphus jujuba Mill.) polysaccharides in a colorectal cancer mouse model[J]. Food & Function,2020,11(1):163−173.
|
[33] |
JI X, HOU C, ZHANG X, et al. Microbiome-metabolomic analysis of the impact of Zizyphus jujuba cv. Muzao polysaccharides consumption on colorectal cancer mice fecal microbiota and metabolites[J]. International Journal of Biological Macromolecules,2019,131:1067−1076. doi: 10.1016/j.ijbiomac.2019.03.175
|
[34] |
WU Z, GAO R, LI H, et al. New insight into the joint significance of dietary jujube polysaccharides and 6-gingerol in antioxidant and antitumor activities[J]. RSC Advances,2021,11(53):33219−33234. doi: 10.1039/D1RA03640H
|
[35] |
张仙土, 付承林, 陈灵斌, 等. 大枣多糖对S-180瘤细胞杀伤性实验研究[J]. 中国现代医生,2012,50(12):20−21. [ZHANG X Z, FU C L, CHEN L B, et al. Effect of polysaccharides on S-180 tumor cells[J]. China Modern Doctor,2012,50(12):20−21.] doi: 10.3969/j.issn.1673-9701.2012.12.009
ZHANG X Z, FU C L, CHEN L B, et al. Effect of polysaccharides on S-180 tumor cells[J]. China Modern Doctor, 2012, 50(12): 20−21. doi: 10.3969/j.issn.1673-9701.2012.12.009
|
[36] |
WU Z, LI H, WANG Y, et al. Optimization extraction, structural features and antitumor activity of polysaccharides from Z. jujuba cv. Ruoqiangzao seeds[J]. International Journal of Biological Macromolecules,2019,135:1151−1161. doi: 10.1016/j.ijbiomac.2019.06.020
|
[37] |
RAMBERG J E, NELSON E D, SINNOTT R A. Immunomodulatory dietary polysaccharides:A systematic review of the literature[J]. Nutrition Journal,2010,9:54. doi: 10.1186/1475-2891-9-54
|
[38] |
李容, 陈华国, 周欣. 植物多糖免疫调节机制研究进展[J]. 天然产物研究与开发,2018,30(11):2017−2022,2031. [LI R, CHEN H G, ZHOU X. Research progress in immunomodulatory mechanisms of plant polysaccharides[J]. Natural Products Research and Development,2018,30(11):2017−2022,2031.]
LI R, CHEN H G, ZHOU X. Research progress in immunomodulatory mechanisms of plant polysaccharides[J]. Natural Products Research and Development, 2018, 30(11): 2017−2022,2031.
|
[39] |
李凤娇, 李敬双, 王一伦, 等. 大枣多糖对小鼠淋巴细胞免疫调节作用的研究[J]. 粮油食品科技,2021,29(1):141−147. [LI F J, LI J S, WANG Y L, et al. Effects of Jujube polysaccharides on immune regulation of mouse lymphocytes[J]. Science and Technology of Cereals, Oils and Foods,2021,29(1):141−147.]
LI F J, LI J S, WANG Y L, et al. Effects of Jujube polysaccharides on immune regulation of mouse lymphocytes[J]. Science and Technology of Cereals, Oils and Foods, 2021, 29(1): 141−147.
|
[40] |
顾有方, 丁静静, 孙运, 等. 大枣多糖对小鼠腹腔巨噬细胞吞噬功能的影响[J]. 中国中医药科技,2009,16(4):290−291. [GU Y F, DING J J, SUN Y, et al. Effects of jujube polysaccharides on phagocytic function of mouse peritoneal macrophages[J]. Chinese Journal of Traditional Medical Science and Technology,2009,16(4):290−291.] doi: 10.3969/j.issn.1005-7072.2009.04.020
GU Y F, DING J J, SUN Y, et al. Effects of jujube polysaccharides on phagocytic function of mouse peritoneal macrophages[J]. Chinese Journal of Traditional Medical Science and Technology, 2009, 16(4): 290−291. doi: 10.3969/j.issn.1005-7072.2009.04.020
|
[41] |
CUI G, ZHANG W, WANG Q, et al. Extraction optimization, characterization and immunity activity of polysaccharides from Fructus Jujubae[J]. Carbohydrate Polymers,2014,111:245−255. doi: 10.1016/j.carbpol.2014.04.041
|
[42] |
牛佳卉, 袁静, 魏然, 等. 红枣多糖对小鼠肠道免疫屏障的保护作用及机制研究[J]. 食品工业科技,2021,42(4):295−300,306. [NIN J H, YANG J, WEI R, et al. Protective effect and mechanism of jujube polysaccharide on intestinal immune barrier in mice[J]. Science and Technology of Food Industry,2021,42(4):295−300,306.]
NIN J H, YANG J, WEI R, et al. Protective effect and mechanism of jujube polysaccharide on intestinal immune barrier in mice[J]. Science and Technology of Food Industry, 2021, 42(4): 295−300,306.
|
[43] |
刘丹丹, 郑丰渠, 苗明三. 大枣多糖对氢化可的松致小鼠免疫抑制模型免疫功能的影响[J]. 中医学报,2011,26(7):809−810. [LIU D D, ZHENG F Q, MIAO M S. Effect of jujube polysaccharide on immune function of hydrocortisone induced mice immune suppression model[J]. Journal of Chinese Medicine,2011,26(7):809−810.]
LIU D D, ZHENG F Q, MIAO M S. Effect of jujube polysaccharide on immune function of hydrocortisone induced mice immune suppression model[J]. Journal of Chinese Medicine, 2011, 26(7): 809−810.
|
[44] |
ZOU M, CHEN Y, SUN-WATERHOUSE D, et al. Immunomodulatory acidic polysaccharides from Zizyphus jujuba cv. Huizao:Insights into their chemical characteristics and modes of action[J]. Food Chemistry,2018,258:35−42. doi: 10.1016/j.foodchem.2018.03.052
|
[45] |
叶美怡, 高明子, 刘佳, 等. 大枣多糖对鸡淋巴细胞免疫功能影响的研究[J]. 饲料研究,2022,45(8):40−43. [YE M Y, GAO M Z, LIU J, et al. Effects of jujube polysaccharides on immune function of chicken lymphocytes[J]. Feed Research,2022,45(8):40−43.]
YE M Y, GAO M Z, LIU J, et al. Effects of jujube polysaccharides on immune function of chicken lymphocytes[J]. Feed Research, 2022, 45(8): 40−43.
|
[46] |
田萌, 毛丽娟, 赵影, 等. 慢性疲劳综合症的发病机制及运动处方制定[J]. 体育科研,2015,36(1):45−48. [TIAN M, MAO L J, ZHAO Y, et al. Pathogenesis and exercise prescription formulation of chronic fatigue syndrome[J]. Sports Science Research,2015,36(1):45−48.] doi: 10.3969/j.issn.1006-1207.2015.01.010
TIAN M, MAO L J, ZHAO Y, et al. Pathogenesis and exercise prescription formulation of chronic fatigue syndrome[J]. Sports Science Research, 2015, 36(1): 45−48. doi: 10.3969/j.issn.1006-1207.2015.01.010
|
[47] |
胡起华, 陈菲. 慢性疲劳综合症中西医研究概述[J]. 云南中医中药杂志,2012,33(4):75−77. [HU Q H, CHEN F. Overview of Chinese and Western studies on chronic fatigue syndrome[J]. Yunnan Journal of Traditional Chinese Medicine and Materia Medica,2012,33(4):75−77.] doi: 10.3969/j.issn.1007-2349.2012.04.046
HU Q H, CHEN F. Overview of Chinese and Western studies on chronic fatigue syndrome[J]. Yunnan Journal of Traditional Chinese Medicine and Materia Medica, 2012, 33(4): 75−77. doi: 10.3969/j.issn.1007-2349.2012.04.046
|
[48] |
冯雯, 张彤, 徐诗静. 从中西医结合医角度谈慢性疲劳综合征[J]. 世界最新医学信息文摘,2016,16(69):266−267. [FENG W, ZHANG T, XU S J. Chronic fatigue syndrome from the perspective of integrated Chinese and Western medicine[J]. World Latest Medical Information,2016,16(69):266−267.]
FENG W, ZHANG T, XU S J. Chronic fatigue syndrome from the perspective of integrated Chinese and Western medicine[J]. World Latest Medical Information, 2016, 16(69): 266−267.
|
[49] |
赵其达拉吐, 孙美艳. 富含大枣多糖食品对运动员缓解运动性疲劳的效果研究[J]. 食品研究与开发,2016,37(18):182−185. [ZHAO Q D L T, SUN M Y. Effect of jujube polysaccharide rich food on relieving exercise fatigue of athletes[J]. Food Research and Development,2016,37(18):182−185.] doi: 10.3969/j.issn.1005-6521.2016.18.043
ZHAO Q D L T, SUN M Y. Effect of jujube polysaccharide rich food on relieving exercise fatigue of athletes[J]. Food Research and Development, 2016, 37(18): 182−185. doi: 10.3969/j.issn.1005-6521.2016.18.043
|
[50] |
马晓宁, 秦令祥, 冀晓龙, 等. Design-Expert软件设计优化内黄大枣多糖的硒化修饰及其抗氧化、抗疲劳作用研究[J]. 食品安全质量检测学报,2023,14(10):164−172. [MA X N, QIN L X, JI X L, et al. Study on selenium modification and anti-oxidation and anti-fatigue effects of polysaccharides of Neihuang jujube by Design-Expert software[J]. Journal of Food Safety & Quality,2023,14(10):164−172.]
MA X N, QIN L X, JI X L, et al. Study on selenium modification and anti-oxidation and anti-fatigue effects of polysaccharides of Neihuang jujube by Design-Expert software[J]. Journal of Food Safety & Quality, 2023, 14(10): 164−172.
|
[51] |
邵长专, 唐刚. 大枣多糖对慢性疲劳综合症大鼠的作用效果[J]. 食品科学,2015,36(1):205−208. [SHAO C Z, TANG G. Effects of polysaccharides from jujube on chronic fatigue syndrome rats[J]. Food Science,2015,36(1):205−208.] doi: 10.7506/spkx1002-6630-201501039
SHAO C Z, TANG G. Effects of polysaccharides from jujube on chronic fatigue syndrome rats[J]. Food Science, 2015, 36(1): 205−208. doi: 10.7506/spkx1002-6630-201501039
|
[52] |
李强, 刘钧珂. 吕梁木枣多糖与交城骏枣多糖的抗疲劳作用比较研究[J]. 中国调味品,2023,48(2):83−86. [LI Q, LIU J K. Comparative study on the anti-fatigue effects of polysaccharides from Lüliang jujube and Jiacheng jujube[J]. Chinese Condiment,2023,48(2):83−86.] doi: 10.3969/j.issn.1000-9973.2023.02.015
LI Q, LIU J K. Comparative study on the anti-fatigue effects of polysaccharides from Lüliang jujube and Jiacheng jujube[J]. Chinese Condiment, 2023, 48(2): 83−86. doi: 10.3969/j.issn.1000-9973.2023.02.015
|
[53] |
GUO X. Effect of jujube date polysaccharide in resisting sports fatigue[J]. Advance Journal of Food Science and Technology,2015,9(12):939−943. doi: 10.19026/ajfst.9.1778
|
[54] |
王凤舞, 沈心荷, 任嘉玮, 等. 大枣多糖对香菇多糖抗疲劳抗氧化的增效作用的研究[J]. 食品科技,2014,39(9):210−215. [WANG F W, SHEN X H, REN J W, et al. Study on the synergistic effect of jujube polysaccharides on fatigue and oxidation resistance of Lentinus edodes polysaccharides[J]. Food Science and Technology,2014,39(9):210−215.]
WANG F W, SHEN X H, REN J W, et al. Study on the synergistic effect of jujube polysaccharides on fatigue and oxidation resistance of Lentinus edodes polysaccharides[J]. Food Science and Technology, 2014, 39(9): 210−215.
|
[55] |
邓昕雨, 马骁. 肝损伤发生机制及其治疗研究进展[J]. 中药与临床,2022,13(5):118−123,128. [DENG X Y, MA X. Progress in the pathogenesis and treatment of liver injury[J]. Pharmacy and Clinics of Chinese Materia Medica,2022,13(5):118−123,128.] doi: 10.3969/j.issn.1674-926X.2022.05.025
DENG X Y, MA X. Progress in the pathogenesis and treatment of liver injury[J]. Pharmacy and Clinics of Chinese Materia Medica, 2022, 13(5): 118−123,128. doi: 10.3969/j.issn.1674-926X.2022.05.025
|
[56] |
池肇春. 药物性肝损伤研究现状与进展[J]. 世界华人消化杂志,2021,29(16):915−925. [CHI Z C. Research status and progress of drug-induced liver injury[J]. Word Chinese Journal of Digestology,2021,29(16):915−925.] doi: 10.11569/wcjd.v29.i16.915
CHI Z C. Research status and progress of drug-induced liver injury[J]. Word Chinese Journal of Digestology, 2021, 29(16): 915−925. doi: 10.11569/wcjd.v29.i16.915
|
[57] |
瞿文生, 尹继业, 高月求, 等. 天然多糖对化学性肝损伤的干预和治疗效果评价研究进展[J]. 国际药学研究杂志,2018,45(12):885−898. [QU W S, YIN J Y, GAO Y Q, et al. Research progress of natural polysaccharides in the treatment of chemical liver injury[J]. Journal of International Pharmaceutical Research,2018,45(12):885−898.]
QU W S, YIN J Y, GAO Y Q, et al. Research progress of natural polysaccharides in the treatment of chemical liver injury[J]. Journal of International Pharmaceutical Research, 2018, 45(12): 885−898.
|
[58] |
张钟, 吴茂东. 大枣多糖对小鼠化学性肝损伤的保护作用和抗疲劳作用[J]. 南京农业大学学报,2006(1):94−97. [ZHANG Z, WU M D. Protective effect and anti-fatigue effect of polysaccharides from jujube on chemical liver injury in mice[J]. Journal of Nanjing Agricultural University,2006(1):94−97.]
ZHANG Z, WU M D. Protective effect and anti-fatigue effect of polysaccharides from jujube on chemical liver injury in mice[J]. Journal of Nanjing Agricultural University, 2006(1): 94−97.
|
[59] |
LIU G, LIU X, ZHANG Y, et al. Hepatoprotective effects of polysaccharides extracted from Zizyphus jujube cv. Huanghetanzao[J]. International Journal of Biological Macromolecules,2015,76:169−175. doi: 10.1016/j.ijbiomac.2015.01.061
|
[60] |
YUE Y, WU S, ZHANG H, et al. Characterization and hepatoprotective effect of polysaccharides from Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H. F. Chou sarcocarp[J]. Food and Chemical Toxicology,2014,74:76−84. doi: 10.1016/j.fct.2014.09.006
|
[61] |
WANG D, ZHAO Y, JIAO Y, et al. Antioxidative and hepatoprotective effects of the polysaccharides from Zizyphus jujube cv. Shaanbeitanzao[J]. Carbohydrate Polymers,2012,88(4):1453−1459. doi: 10.1016/j.carbpol.2012.02.046
|
[62] |
苗明三, 魏荣锐. 大枣多糖对乙硫氨酸及扑热息痛所致小鼠肝损伤模型的保护作用[J]. 中华中医药杂志,2010,25(8):1290−1292. [MIAO M S, WEI R R. Protective effect of polysaccharides from jujube on liver injury induced by ethothione and paracetamol in mice[J]. Journal of Chinese Traditional Medicine,2010,25(8):1290−1292.]
MIAO M S, WEI R R. Protective effect of polysaccharides from jujube on liver injury induced by ethothione and paracetamol in mice[J]. Journal of Chinese Traditional Medicine, 2010, 25(8): 1290−1292.
|
[63] |
杨生海, 陈建茂, 马磊, 等. 大枣渣多糖对CCl4肝损伤小鼠的保护作用[J]. 宁夏医科大学学报,2011,33(9):874−875,902. [YANG S H, CHEN J M, MA L, et al. Protective effect of polysaccharides from jujube residue on CCl4 liver injury in mice[J]. Journal of Ningxia Medical University,2011,33(9):874−875,902.] doi: 10.3969/j.issn.1674-6309.2011.09.026
YANG S H, CHEN J M, MA L, et al. Protective effect of polysaccharides from jujube residue on CCl4 liver injury in mice[J]. Journal of Ningxia Medical University, 2011, 33(9): 874−875,902. doi: 10.3969/j.issn.1674-6309.2011.09.026
|
[64] |
苗明三, 苗艳艳, 魏荣锐. 大枣多糖对CCl4所致大、小鼠肝损伤模型的保护作用[J]. 中华中医药杂志,2011,26(9):1997−2000. [MIAO M S, MIAO Y Y, WEI R R. Protective effect of polysaccharides from jujube on liver injury induced by CCl4 in rats and mice[J]. Journal of Chinese Traditional Medicine,2011,26(9):1997−2000.]
MIAO M S, MIAO Y Y, WEI R R. Protective effect of polysaccharides from jujube on liver injury induced by CCl4 in rats and mice[J]. Journal of Chinese Traditional Medicine, 2011, 26(9): 1997−2000.
|
[65] |
中国居民营养与慢性病状况报告(2020年)[J]. 营养学报,2020,42(6):521. [Report on nutrition and chronic diseases in China[J]. Acta Nutriologica Sinica,2020,42(6):521.]
Report on nutrition and chronic diseases in China[J]. Acta Nutriologica Sinica, 2020, 42(6): 521.
|
[66] |
张丽雯, 阮梅花, 刘加兰, 等. 糖尿病领域研发态势分析[J]. 遗传,2022,44(10):824−839. [ZHANG L W, RUAN M H, LIU J L, et al. Research and development situation analysis in diabetes field[J]. Heredity,2022,44(10):824−839.]
ZHANG L W, RUAN M H, LIU J L, et al. Research and development situation analysis in diabetes field[J]. Heredity, 2022, 44(10): 824−839.
|
[67] |
李结文. 2型糖尿病合并高血压患者血脂、血糖代谢情况及其与高血压病程的关系分析[J]. 智慧健康,2023,9(1):85−88. [LI J W. Analysis on the metabolism of blood lipid and blood glucose and its relationship with the course of hypertension in patients with type 2 diabetes mellitus[J]. Wisdom and Health,2023,9(1):85−88.]
LI J W. Analysis on the metabolism of blood lipid and blood glucose and its relationship with the course of hypertension in patients with type 2 diabetes mellitus[J]. Wisdom and Health, 2023, 9(1): 85−88.
|
[68] |
谢雨彤, 罗依扎·瓦哈甫, 杨洁. 红枣多糖对链脲佐菌素诱导的糖尿病小鼠的降血糖作用[J]. 食品科技,2018,43(9):244−250. [XIE Y T, LUO Y Z·W H P, YANG J. Hypoglycemic effects of jujube polysaccharides on streptozotocin induced diabetic mice[J]. Food Science and Technology,2018,43(9):244−250.]
XIE Y T, LUO Y Z·W H P, YANG J. Hypoglycemic effects of jujube polysaccharides on streptozotocin induced diabetic mice[J]. Food Science and Technology, 2018, 43(9): 244−250.
|
[69] |
ZHAO Y, YANG X, REN D, et al. Preventive effects of jujube polysaccharides on fructose-induced insulin resistance and dyslipidemia in mice[J]. Food & Function,2014,5(8):1771−1778.
|
[70] |
JI X, LIU F, PENG Q, et al. Purification, structural characterization, and hypolipidemic effects of a neutral polysaccharide from Ziziphus jujuba cv. Muzao[J]. Food Chemistry,2018,245:1124−1130. doi: 10.1016/j.foodchem.2017.11.058
|
[71] |
龚频, 王佩佩, 同美霖, 等. 红枣多糖的提取工艺及药理活性研究[J]. 食品工业科技,2022,43(13):198−207. [GONG P, WANG P P, TONG M L, et al. Study on extraction technology and pharmacological activity of polysaccharides from jujube[J]. Science and Technology of Food Industry,2022,43(13):198−207.]
GONG P, WANG P P, TONG M L, et al. Study on extraction technology and pharmacological activity of polysaccharides from jujube[J]. Science and Technology of Food Industry, 2022, 43(13): 198−207.
|
[72] |
罗依扎·瓦哈甫, 骆新, 谢飞, 等. 红枣多糖对小鼠血糖及血清胰岛素水平影响的初步研究[J]. 食品工业科技,2012,33(22):369−371,374. [LUO Y Z·W H P, LUO X, XIE F, et al. Effects of polysaccharides from red jujube on blood glucose and serum insulin levels in mice[J]. Science and Technology of Food Industry,2012,33(22):369−371,374.]
LUO Y Z·W H P, LUO X, XIE F, et al. Effects of polysaccharides from red jujube on blood glucose and serum insulin levels in mice[J]. Science and Technology of Food Industry, 2012, 33(22): 369−371,374.
|
[73] |
商常发, 赵芝刚, 顾有方, 等. 大枣多糖对大鼠血清钙和葡萄糖水平的影响[J]. 中国中医药科技,2007(2):102−103. [SHANG C F, ZHAO Z G, GU Y F, et al. Effects of polysaccharides from jujube on serum calcium and glucose levels in rats[J]. Chinese Journal of Traditional Medical Science and Technology,2007(2):102−103.] doi: 10.3969/j.issn.1005-7072.2007.02.018
SHANG C F, ZHAO Z G, GU Y F, et al. Effects of polysaccharides from jujube on serum calcium and glucose levels in rats[J]. Chinese Journal of Traditional Medical Science and Technology, 2007(2): 102−103. doi: 10.3969/j.issn.1005-7072.2007.02.018
|
[74] |
XU D, XIAO J, JIANG D, et al. Inhibitory effects of a water-soluble jujube polysaccharide against biofilm-forming oral pathogenic bacteria[J]. International Journal Biological Macromolecules,2022,208:1046−1062. doi: 10.1016/j.ijbiomac.2022.03.196
|
[75] |
徐瑜玲, 苗明三, 孙艳红, 等. 大枣多糖对气血双虚模型小鼠造血功能的影响[J]. 中国临床康复,2004(24):5050−5051. [XU Y L, MIAO M S, SUN Y H, et al. Effect of jujube polysaccharide on hematopoietic function of mice with Qi and blood deficiency[J]. Chinese Journal of Clinical Rehabilitation,2004(24):5050−5051.]
XU Y L, MIAO M S, SUN Y H, et al. Effect of jujube polysaccharide on hematopoietic function of mice with Qi and blood deficiency[J]. Chinese Journal of Clinical Rehabilitation, 2004(24): 5050−5051.
|
[76] |
HUANG S, JIANG X, CHEN Q, et al. Jujube polysaccharides mitigated anemia in rats with chronic kidney disease:Regulation of short chain fatty acids release and erythropoietin production[J]. Journal of Functional Foods,2021,86:104673. doi: 10.1016/j.jff.2021.104673
|
[77] |
周文君, 池建伟, 易阳, 等. 龙眼、枸杞和红枣多糖的理化性质及其协同益生活性[J]. 现代食品科技,2021,37(11):58−67. [ZHOU W J, CHI J W, YI Y, et al. Physicochemical properties and synergistic probiotics of polysaccharides from longan, wolfberry and jujube[J]. Modern Food Science and Technology,2021,37(11):58−67.]
ZHOU W J, CHI J W, YI Y, et al. Physicochemical properties and synergistic probiotics of polysaccharides from longan, wolfberry and jujube[J]. Modern Food Science and Technology, 2021, 37(11): 58−67.
|
[78] |
HAN X, ZHOU Q, GAO Z, et al. In vitro digestion and fecal fermentation behaviors of polysaccharides from Ziziphus Jujuba cv. Pozao and its interaction with human gut microbiota[J]. Food Research International, 2022, 162(Pt A):112022.
|
[79] |
王娜, 冯艳风, 范会平, 等. 大枣粗多糖体外抗凝血活性的差异化研究[J]. 中国食品学报,2013,13(12):34−39. [WANG N, FENG Y F, FAN H P, et al. Differentiation of anticoagulant activity of crude polysaccharides from jujube in vitro[J]. Journal of Chinese Institute of Food Science and Technology,2013,13(12):34−39.]
WANG N, FENG Y F, FAN H P, et al. Differentiation of anticoagulant activity of crude polysaccharides from jujube in vitro[J]. Journal of Chinese Institute of Food Science and Technology, 2013, 13(12): 34−39.
|
[80] |
苗明三, 苗艳艳, 孙艳红. 大枣多糖对血虚大鼠全血细胞及红细胞ATP酶活力的影响[J]. 中国临床康复,2006(11):97−99. [MIAO M S, MIAO Y Y, SUN Y H. Effect of jujube polysaccharide on ATPase activity of whole blood cells and red blood cells in rats with blood deficiency[J]. Chinese Journal of Clinical Rehabilitation,2006(11):97−99.]
MIAO M S, MIAO Y Y, SUN Y H. Effect of jujube polysaccharide on ATPase activity of whole blood cells and red blood cells in rats with blood deficiency[J]. Chinese Journal of Clinical Rehabilitation, 2006(11): 97−99.
|
[81] |
HUANG Y L, YEN G C, SHEU F, et al. Effects of water-soluble carbohydrate concentrate from Chinese jujube on different intestinal and fecal indices[J]. Journal of Agricultural and Food Chemistry,2008,56(5):1734−1739.
|
1. |
张鹏,王延锋,史磊,闫水华,王金贺,刘姿彤,葛欣然,赵静. 蜜环菌菌种选育及多糖药理活性的研究进展. 食药用菌. 2024(02): 104-108+148 .
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