Research Progress of Magnetic Molecularly Imprinted Polymers in Separation and Purification of Natural Active Substances

Magnetic molecularly imprinted polymers are novel separation materials assembled by magnetic nanoparticles and molecularly imprinted polymers, with specific selectivity, easy separation and regeneration, which can be used in the preliminary treatment of food and drugs, and the separation and purification of natural active substances. Herein, the preparation principle and method of magnetic molecular imprinting technology are elucidated, and the research progress (2017~2022) of magnetic molecular imprinting polymers in the separation and purification of natural active substances, such as polyphenols, alkaloids, organic acids, terpenoids, and macromolecules are reviewed. Meanwhile, the difficulties in the field of separation and purification are discussed. This review will provide reference for the enrichment, purification, analysis and detection of natural active substances.