Citation: | WANG Ni, CHEN Mengxia, MENG Fanqiang, et al. Extraction of Polysaccharide from Zingiber officinale Roscoe and Its Regulatory Effect on Intestinal Flora in Diabetic Mice[J]. Science and Technology of Food Industry, 2023, 44(4): 278−286. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2022060155. |
[1] |
MENINI S, IACOBINI C, VITALE M, et al. The inflammasome in chronic complications of diabetes and related metabolic disorders[J]. Cells,2020,9(8):1−27.
|
[2] |
UNAI G, ASIER B, SHIFA J, et al. Pathophysiology of type 2 diabetes mellitus[J]. International Journal of Molecular Sciences,2020,21(17):1−34.
|
[3] |
MIN X, LIU R, FU B, et al. Correlation analysis combined with a floating reference measurement to improve the prediction accuracy of glucose in scattering media[J]. Applied Spectroscopy,2017,71(9):2076−2082. doi: 10.1177/0003702817712227
|
[4] |
尹军霞, 林德荣. 肠道菌群与疾病[J]. 生物学通报,2004,53(3):26−28. [YIN J X, LIN D R. Gut flora and disease[J]. Bulletin of Biology,2004,53(3):26−28. doi: 10.3969/j.issn.0006-3193.2004.03.013
|
[5] |
LI Y G, XU W Y, ZHANG F, et al. The gut microbiota-produced indole-3-propionic acid confers the antihyperlipidemic effect of mulberry-derived 1-deoxynojirimycin[J]. Msystems,2020,5(5):1−15.
|
[6] |
LARSEN N, VOGENSEN F K, VAN DEN BERG F W J, et al. Gut microbiota in human adults with type 2 diabetes differs from non-diabetic adults[J]. PloS One,2010,5(2):1−10.
|
[7] |
WU H, ESTEVE E, TREMAROLI V, et al. Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug[J]. Nature Medicine,2017,23(7):850−858. doi: 10.1038/nm.4345
|
[8] |
中国2型糖尿病防治指南(2020年版)(上)[J]. 中国实用内科杂志, 2021, 41(8): 668−695
Guideline for the prevention and treatment of type 2 diabetes mellitus in China (2020 edition) (Part 1)[J]. Chinese Journal of Practical Internal Medicine, 2021, 41(8): 668−695.
|
[9] |
VIJAN S, SUSSMAN J B, YUDKIN J S, et al. Effect of patients' risks and preferences on health gains with plasma glucose level lowering in type 2 diabetes mellitus[J]. Jama Internal Medicine,2014,174(8):1227−1234. doi: 10.1001/jamainternmed.2014.2894
|
[10] |
王秋霞, 贾美艳, 唐荣平, 等. 天然药物中降血糖成分的研究进展[J]. 中国民族民间医药杂志,2005,14(4):190−193, 248. [WANG Q X, JIA M Y, TANG R P, et al. The chemical constituents review of decreasing blood glucose in natural products[J]. Chinese Journal of Ethnomedicine and Ethnopharmacy,2005,14(4):190−193, 248.
|
[11] |
唐圆, 谢果珍. 多糖与肠道菌群的相互作用研究进展[J]. 现代农业科技,2020,49(9):225−227. [TANG G, XIE G Z. Research progress on interaction between polysaccharide and gut microbiota[J]. Modern Agricultural Science and Technology,2020,49(9):225−227. doi: 10.3969/j.issn.1007-5739.2020.09.135
|
[12] |
单峰, 黄璐琦, 郭娟, 等. 药食同源的历史和发展概况[J]. 生命科学,2015,27(8):1061−1069. [SHAN F, HUANG L Q, GUO J, et al. History and development of "One Root of Medicine and Food"[J]. Chinese Bulletin of Life Sciences,2015,27(8):1061−1069.
|
[13] |
李大峰, 贾冬英, 姚开, 等. 生姜及其提取物在食品加工中的应用[J]. 中国调味品,2011,36(2):20−23, 39. [LI D F, JIA D Y, YAO K, et al. Applications of ginger and its extract in food processing[J]. China Condiment,2011,36(2):20−23, 39. doi: 10.3969/j.issn.1000-9973.2011.02.007
|
[14] |
SUGIMOTO N, KATAKURA M, MATSUZAKI K, et al. Ginger facilitates cell migration and heat tolerance in mouse fibroblast cells[J]. Molecular Medicine Reports,2021,23(4):1−8.
|
[15] |
项佳媚, 许利嘉, 肖伟, 等. 姜的研究进展[J]. 中国药学杂志,2017,52(5):353−357. [XIANG J M, XU L J, XIAO W, et al. Research progress in Zingiber officinale[J]. Chinese Pharmaceutical Journal,2017,52(5):353−357.
|
[16] |
RAAFAT M, EL-SAYED A S A, EL-SAYED M T. Biosynthesis and anti-mycotoxigenic activity of Zingiber officinale Roscoe-derived metal nanoparticles[J]. Molecules,2021,26(8):1−13.
|
[17] |
赵文竹, 张瑞雪, 于志鹏, 等. 生姜的化学成分及生物活性研究进展[J]. 食品工业科技,2016,37(11):383−389. [ZHAO W Z, ZHANG R X, YU Z P, et al. Research progress in ginger chemical composition and biological activity[J]. Science and Technology of Food Industry,2016,37(11):383−389. doi: 10.13386/j.issn1002-0306.2016.11.070
|
[18] |
HOU M D, JUN G, LIU Z Q, et al. Antioxidant and immunomodulatory activitiesin vitro of a neutral polysaccharide from ginger (Zingiber officinale)[J]. Starch-Starke,2021,73(9−10):2100048. doi: 10.1002/star.202100048
|
[19] |
LIAO D W, CHENG C, LIU J P, et al. Characterization and antitumor activities of polysaccharides obtained from ginger (Zingiber officinale) by different extraction methods[J]. International Journal of Biological Macromolecules,2020,152:894−903. doi: 10.1016/j.ijbiomac.2020.02.325
|
[20] |
WANG C F, HE Y X, TANG X Z, et al. Sulfation, structural analysis, and anticoagulant bioactivity of ginger polysaccharides[J]. Journal of Food Science,2020,85(8):2427−2434. doi: 10.1111/1750-3841.15338
|
[21] |
CHEN X H, WANG Z R, KAN J Q. Polysaccharides from ginger stems and leaves: Effects of dual and triple frequency ultrasound assisted extraction on structural characteristics and biological activities[J]. Food Bioscience,2021,42:101166. doi: 10.1016/j.fbio.2021.101166
|
[22] |
冯鑫, 夏宇, 陈贵堂, 等. 生姜皮多糖的分离纯化及其结构组成分析[J]. 食品科学,2017,38(6):185−190. [FENG X, XIA Y, CHEN G T, et al. Purification and structural analysis of polysaccharide from ginger peels[J]. Food Science,2017,38(6):185−190. doi: 10.7506/spkx1002-6630-201706029
|
[23] |
陈丽娟. 银耳多糖快速提取及可控降解的研究[D]. 广州: 华南理工大学, 2017
CHEN L J. Research on fast extraction and controlled degradation of polysaccharide from tremella[D]. Guangzhou: South China University of Technology, 2017.
|
[24] |
王琳炜. 霍山铁皮石斛多糖DOPA-1的结构特征及对HepG2细胞凋亡的影响[D]. 镇江: 江苏大学, 2017
WANG L W. Structural characterization of polysaccharide DOPA-1 isolated from Dendrobium officinale Kimura et Migo in Huoshan and its apoptosis effect on HepG2 cell[D]. Zhenjiang: Jiangsu University, 2017.
|
[25] |
杨永涛. 罗布麻总黄酮的提取、分离纯化及其抗氧化性能研究[D]. 广州: 华南理工大学, 2018
YANG Y T. Study on extraction, purification and antioxidant activity of total flavonoids from Apocynum venetum[D]. Guangzhou: South China University of Technology, 2018.
|
[26] |
李守鹏. 生姜中抗氧化成分的提取及其抗痴呆效果的研究[D]. 泰安: 山东农业大学, 2015
LI S P. Study on extraction and anti-dementia effects of antioxidant constituents from ginger[D]. Taian: Shandong Agricultural University, 2015.
|
[27] |
DUBOIS M, GILLES K A, HAMILTON J K, et al. Colorimetric method for determination of sugars and related substances[J]. Analytical Chemistry,1956,28(3):350−356. doi: 10.1021/ac60111a017
|
[28] |
BRADFORD M M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding[J]. Analytical Biochemistry,1976,72:248−254. doi: 10.1016/0003-2697(76)90527-3
|
[29] |
LI C, HUANG Q, FU X, et al. Characterization, antioxidant and immunomodulatory activities of polysaccharides from Prunella vulgaris Linn[J]. International Journal of Biological Macromolecules,2015,75:298−305. doi: 10.1016/j.ijbiomac.2015.01.010
|
[30] |
沈赤. 绍兴黄酒多糖的分离提取、生物活性及其对肠道微生物的影响[D]. 无锡: 江南大学, 2014
SHEN C. The separation and extraction, biological activities of polysaccharides from Shanxing rice wine and their effects on intestinal microflora[D]. Wuxi: Jiangnan University, 2014.
|
[31] |
JIAO Y K, WANG X Q, JIANG X, et al. Antidiabetic effects of Morus alba fruit polysaccharides on high-fat diet- and streptozotocin-induced type 2 diabetes in rats[J]. Journal of Ethnopharmacology,2017,199:119−127. doi: 10.1016/j.jep.2017.02.003
|
[32] |
王昭珺, 刘晓风, 徐也. 兰州百合芯多糖的提取工艺及其体外抗氧化活性[J]. 现代食品科技,2020,36(9):219−227, 201. [WANG Z J, LIU X F, XU Y. Extraction process of polysaccharides from Lanzhou Lily Cores and evaluation of their antioxidant activity in vitro[J]. Modern Food Science and Technology,2020,36(9):219−227, 201. doi: 10.13982/j.mfst.1673-9078.2020.9.0258
|
[33] |
朱成香. 黄精多糖抗铅-镉复合重金属致肝损伤药效学评价及作用机制研究[D]. 贵阳: 贵州师范大学, 2021
ZHU C X. Pharmacodynamic evaluation and mechanism study of Polygonatum polysaccharide on liver injury induced by lead-cadmium complex heavy metals[D]. Guiyang: Guizhou Normal University, 2021.
|
[34] |
宋振康. 元蘑多糖的提取及其缓解体力疲劳功能的研究[D]. 长春: 长春工业大学, 2021
SONG Z K. Extraction and alleviate physical fatigue of polysaccharide from Hohenbuehelia serotina[D]. Changchun: Changchun University Of Technology, 2021.
|
[35] |
夏宇. 生姜皮多糖的分离纯化、结构分析及其抗氧化活性研究[D]. 南京: 南京农业大学, 2016
XIA Y. Research on extraction, purification, structural analysis and antioxidant activity of polysaccharides from the ginger skin[D]. Nanjing: Nanjing Agricultural University, 2016.
|
[36] |
李波, 张亚茹, 周娅丽, 等. 灵芝三萜和多糖提取工艺研究[J]. 食用菌,2022,44(2):54−57. [LI B, ZHANG Y R, ZHOU Y L, et al. Study on extraction technology of triterpenes and polysaccharides from Ganoderma lucidum[J]. Edible Fungi,2022,44(2):54−57. doi: 10.3969/j.issn.1000-8357.2022.02.018
|
[37] |
马丽媛, 尚尔坤, 张金凤, 等. 超声波辅助复合酶法提取芦荟多糖的研究[J]. 中国食品添加剂,2022,33(3):51−56. [MA L Y, SHANG E K, ZHANG J F, et al. Study on the extraction of aloe polysaccharide by ultrasound assisted compound enzyme[J]. China Food Additives,2022,33(3):51−56. doi: 10.19804/j.issn1006-2513.2022.03.008
|
[38] |
巩晓佩. 硫酸化修饰红枣多糖的结构表征及生物活性的研究[D]. 石河子: 石河子大学, 2021
GONG X P. Study on the structure characterization and biological activity of sulfated modified jujube polysaccharide[D]. Shihezi: Shihezi University, 2021.
|
[39] |
孙明杰, 张越, 姚亮, 等. 茯苓多糖的分离纯化、组成及其抗氧化活性研究[J]. 安徽中医药大学学报,2022,41(1):86−91. [SUN M J, ZHANG Y, YAO L, et al. Isolation, purification, composition, and antioxidant activity of Poria cocos polysaccharides[J]. Journal of Anhui University of Chinese Medicine,2022,41(1):86−91. doi: 10.3969/j.issn.2095-7246.2022.01.017
|
[40] |
宋丽丽, 闻格, 霍姗浩, 等. 小黄姜多糖的分离纯化及其结构特征及抗氧化活性研究[J]. 食品与发酵工业,2020,46(12):73−79. [SONG L L, WEN G, HUO S H, et al. Isolation, purification, structural characterization and antioxidant activity of polysaccharide from Zingiber officinale Roscoe[J]. Food and Fermentation Industries,2020,46(12):73−79. doi: 10.13995/j.cnki.11-1802/ts.023519
|
[41] |
BAI Z Y, MENG J X, HUANG J X, et al. Comparative study on antidiabetic function of six legume crude polysaccharides[J]. International Journal of Biological Macromolecules,2020,154:25−30. doi: 10.1016/j.ijbiomac.2020.03.072
|
[42] |
王晓梅, 张忠山, 郑卫红, 等. 生姜多糖的提取纯化工艺及鉴定[J]. 中国调味品,2011,36(5):44−46, 51. [WANG X M, ZHANG Z S, ZHENG W H, et al. Extraction, purification and identification of polysaccharide from ginger[J]. China Condiment,2011,36(5):44−46, 51. doi: 10.3969/j.issn.1000-9973.2011.05.013
|
[43] |
GUARNER F, MALAGELADA J R. Gut flora in health and disease[J]. Lancet,2003,361(9356):512−519. doi: 10.1016/S0140-6736(03)12489-0
|
[44] |
郑子明. 香菇多糖药代动力学及其体内吸收代谢机制研究[D]. 武汉: 华中科技大学, 2019
ZHENG Z M. Study on pharmacokinetics of polysaccharide from Lentinus edodes and its mechanism of absorption and metabolism in vivo[D]. Wuhan: Huazhong University of Science and Technology, 2019.
|
[45] |
DONG J, LIANG Q X, NIU Y, et al. Effects of Nigella sativa seed polysaccharides on type 2 diabetic mice and gut microbiota[J]. International Journal of Biological Macromolecules,2020,159:725−738. doi: 10.1016/j.ijbiomac.2020.05.042
|
[46] |
KONIKOFF T, GOPHNA U. Oscillospira: A central, enigmatic component of the human gut micropiota[J]. Trends in Microbiology,2016,24(7):523−524. doi: 10.1016/j.tim.2016.02.015
|
[47] |
WEI X Y, TAO J H, XIAO S W, et al. Xiexin Tang improves the symptom of type 2 diabetic rats by modulation of the gut microbiota[J]. Scientific Reports,2018,8(1):1−12.
|
[48] |
OTTMAN N, GEERLINGS S Y, AALVINK S, et al. Action and function of Akkermansia muciniphila in microbiome ecology, health and disease[J]. Best Practice & Research Clinical Gastroenterology,2017,31(6):637−642.
|
[49] |
PEDERSEN H K, GUDMUNDSDOTTIR V, NIELSEN H B, et al. Human gut microbes impact host serum metabolome and insulin sensitivity[J]. Nature,2016,535(7612):376−381. doi: 10.1038/nature18646
|
[50] |
LIU F P, LING Z X, XIAO Y H, et al. Alterations of urinary microbiota in type 2 diabetes mellitus with hypertension and/or hyperlipidemia[J]. Frontiers in Physiology,2017(8):1−11.
|