WANG Wenli, ZHANG Jinling, WEI Yaning, et al. Extraction, Purification and Bioactivity of Natural Polysaccharides: A Review[J]. Science and Technology of Food Industry, 2022, 43(22): 470−480. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2021120256.
Citation: WANG Wenli, ZHANG Jinling, WEI Yaning, et al. Extraction, Purification and Bioactivity of Natural Polysaccharides: A Review[J]. Science and Technology of Food Industry, 2022, 43(22): 470−480. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2021120256.

Extraction, Purification and Bioactivity of Natural Polysaccharides: A Review

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  • Received Date: December 22, 2021
  • Available Online: September 12, 2022
  • Many researchers have confirmed that natural polysaccharides have the effects of antioxidation, anti-aging, anti-tumor, reducing blood glucose and regulating intestinal flora. Consequently, natural polysaccharides have good development potential and application prospects in the fields of biomedicine, food, and health products. Recently, the extraction, purification, physicochemical properties, and bioactivities of natural polysaccharides have been drawing much attention from scholars around the world. However, different raw materials, extraction, and purification methods lead to differences in the structure and bioactivities of natural polysaccharides. This paper systematically reviews the latest extraction, separation and purification methods, and the hottest biological activities of natural polysaccharides to provide an important reference for plant polysaccharides as functional food and effective therapeutic drugs, and provide an important basis for the development of food based on human health in the future.
  • [1]
    边亮, 陈华国, 周欣. 植物多糖的抗肿瘤活性研究进展[J]. 食品科学,2020,41(7):275−282. [BIAN L, CHEN H G, ZHOU X. Recent advances in understanding the antitumor activity of polysaccharides from plants[J]. Food Science,2020,41(7):275−282. doi: 10.7506/spkx1002-6630-20190330-392
    [2]
    JIN W, XIANG L, PENG D, et al. Study on the coupling progress of thermo-induced anthocyanins degradation and polysaccharides gelation[J]. Food Hydrocolloids,2020,105:105822. doi: 10.1016/j.foodhyd.2020.105822
    [3]
    LI N, WANG C, GEORGIEV M I, et al. Advances in dietary polysaccharides as anticancer agents: Structure-activity relationship[J]. Trends in Food Science & Technology,2021,111:360−377.
    [4]
    YMZAB C, LCPAB C, LJZAB C, et al. Chemical structure and antioxidant activity of a polysaccharide from Siraitia grosvenorii[J]. International Journal of Biological Macromolecules,2020,165:1900−1910. doi: 10.1016/j.ijbiomac.2020.10.127
    [5]
    KELLER M B, BADINO S F, BLOSSOM B M, et al. Promoting and impeding effects of Lytic polysaccharide monooxygenases on glycoside hydrolase activity[J]. ACS Sustainable Chemistry and Engineering,2020,8(37):14117−14126. doi: 10.1021/acssuschemeng.0c04779
    [6]
    LUAN F, JI Y, PENG L, et al. Extraction, purification, structural characteristics and biological properties of the polysaccharides from codonopsis pilosula: A review[J]. Carbohydrate Polymers,2021,261(12):117863.
    [7]
    陈超. 榛蘑多糖的提取, 纯化及体外降血脂研究[D]. 哈尔滨: 东北农业大学, 2017

    CHEN C. Extraction, purification and lowing plasma cholseterol in vitro of polysaccharide from Armillaria Mellea[D]. Harbin: Northeast Agricultural University, 2017.
    [8]
    覃海元, 潘嫣丽, 覃梅珍. 热水与超声波提取鹿角灵芝多糖工艺比较研究[J]. 中国食品添加剂,2011,6(3):91−95. [QIN H Y, PAN Y L, QIN M Z. Comparative study polysaccharide extraction from antler-shape ganoderma lucidum by hot-water and ultrasonic wave[J]. China Food Additives,2011,6(3):91−95. doi: 10.3969/j.issn.1006-2513.2011.03.014
    [9]
    SHAKHMATOV E G, MAKAROVA E N, BELYY V A. Structural studies of biologically active pectin-containing polysaccharides of pomegranate Punica granatum[J]. International Journal of Biological Macromolecules,2018,122:29−36.
    [10]
    SHU Y. Research on extraction condition and anti-oxidation of jujube polysaccharide[J]. Food & Machinery,2012,28(4):117−120.
    [11]
    LIU H M, WANG F Y, LIU Y L. Hot-compressed water extraction of polysaccharides from soy hulls[J]. Food Chemistry,2016,202:104−109. doi: 10.1016/j.foodchem.2016.01.129
    [12]
    TANG Y, XIAO Y, TANG Z, et al. Extraction of polysaccharides from Amaranthus hybridus L. by hot water and analysis of their antioxidant activity[J]. Peer J,2019,7:e7149. doi: 10.7717/peerj.7149
    [13]
    GAN C Y, LATIFF A A. Extraction of antioxidant pectic-polysaccharide from mangosteen (Garcinia mangostana) rind: Optimization using response surface methodology[J]. Carbohydrate Polymers,2011,83(2):600−607. doi: 10.1016/j.carbpol.2010.08.025
    [14]
    YUN L, LI D, YANG L, et al. Hot water extraction and artificial simulated gastrointestinal digestion of wheat germ polysaccharide[J]. International journal of biological macromolecules,2018,123:174−181.
    [15]
    ZHOU P, EID M, XIONG W, et al. Comparative study between cold and hot water extracted polysaccharides from Plantago ovata seed husk by using rheological methods[J]. Food Hydrocolloids,2020,101:105465. doi: 10.1016/j.foodhyd.2019.105465
    [16]
    KERBOUA K A, BENOSMANE L, NAMOUNE S, et al. Anti-inflammatory and antioxidant activity of the hot water-soluble polysaccharides from Anacyclus pyrethrum L. Lag. roots[J]. Journal of Ethnopharmacology,2021,281(1):114491.
    [17]
    FAN T, HU J, FU L, et al. Optimization of enzymolysis-ultrasonic assisted extraction of polysaccharides from Momordica charabtia L. by response surface methodology[J]. Carbohydrate Polymers,2015,115:701−706. doi: 10.1016/j.carbpol.2014.09.009
    [18]
    ZHANG F, DING H, CAO Y, et al. Study on ultrasonic-assisted extraction of polysaccharides fromfruiting body of Armillaria luteo-virens[J]. Science and Technology of Food Industry,2012,33(9):218−221.
    [19]
    曹丹, 孙于寒, 彭浩, 等. 均匀设计法优化灰树花多糖超声波辅助提取工艺及其抗氧化活性分析[J]. 食品研究与开发,2021,42(5):113−118. [CAO D, SUN Y H, PENG H, et al. Optimization of ultrasonic-assisted extraction process of polysaccharides from Grifola frondosa by uniform design and its antioxidant activity analysis[J]. Food Research and Development,2021,42(5):113−118.
    [20]
    杨燕敏, 郑振佳, 高琳, 等. 红枣多糖超声波提取、结构表征及抗氧化活性评价[J]. 食品与发酵工业,2021,47(5):120−126. [YANG Y M, ZHENG Z J, GAO L, et al. Ultrasonic extraction of jujube polysaccharide and its structure and antioxidant activity characterization[J]. Food and Fermentation Industries,2021,47(5):120−126. doi: 10.13995/j.cnki.11-1802/ts.025592
    [21]
    SONG J, DONG S, HANG S, et al. Optimization of ultrasonic extraction of Lycium barbarum polysaccharides using response surface methodology[J]. International Journal of Food Engineering,2020,16(11):20200153.
    [22]
    LUO J, SUN Q, MA Z, et al. Ultrasonic extraction, structural characterization, and bioactivities of nonstarch polysaccharides from red yeast rice[J]. Biotechnology and Applied Biochemistry,2020,67(2):273−286. doi: 10.1002/bab.1844
    [23]
    XIE J H, XIE M Y, SHEN M Y, et al. Optimisation of microwave‐assisted extraction of polysaccharides from Cyclocarya paliurus (Batal. ) Iljinskaja using response surface methodology[J]. Journal Science Food Agriculture,2010,90(8):1353−1360. doi: 10.1002/jsfa.3935
    [24]
    KUMAR C S, SIVAKUMAR M, RUCKMANI K. Microwave-assisted extraction of polysaccharides from Cyphomandra betacea and its biological activities[J]. International Journal of Biological Macromolecules,2016,92:682−693. doi: 10.1016/j.ijbiomac.2016.07.062
    [25]
    陈晓辉, 陈雨婕, 闻正顺, 等. 正交试验优选微波辅助提取火麻仁多糖的工艺[J]. 安徽农业科学,2021,49(6):166−169. [CHEN X H, CHEN Y J, WEN Z S, et al. Optimization of microwave-assisted extraction process of hemp seed polysaccharide based on orthogonal experiment[J]. Journal of Anhui Agricultural Sciences,2021,49(6):166−169. doi: 10.3969/j.issn.0517-6611.2021.06.045
    [26]
    AL-DHABI A, PONMURUGAN K. Microwave assisted extraction and characterization of polysaccharide from waste jamun fruit seeds[J]. International Journal of Biological Macromolecules,2020,152:1157−1163. doi: 10.1016/j.ijbiomac.2019.10.204
    [27]
    CHEN Y, XUE Y. Optimization of microwave assisted extraction, chemical characterization and antitumor activities of polysaccharides from Porphyra haitanensis[J]. Carbohydrate Polymers,2019,206:179−186. doi: 10.1016/j.carbpol.2018.10.093
    [28]
    XU L, YU J, WANG X, et al. Microwave extraction optimization using the response surface methodology of fructus meliae toosendan polysaccharides and its antioxidant activity[J]. International Journal of Biological Macromolecules,2018,118:1501−1510. doi: 10.1016/j.ijbiomac.2018.06.172
    [29]
    YIN X, YOU Q, JIANG Z. Optimization of enzyme assisted extraction of polysaccharides from Tricholoma matsutake by response surface methodology[J]. Carbohydrate Polymers,2011,86(3):1358−1364. doi: 10.1016/j.carbpol.2011.06.053
    [30]
    温思萌, 王亚冬, 昝立峰, 等. 响应面优化酶法提取茯苓多糖工艺[J]. 中国食品添加剂,2021,32(8):36−43. [WEN S M, WANG Y D, MIN L F, et al. Optimization of enzymatic extraction of pachyman from Poria cocos by response surface methodology[J]. China Food Additives,2021,32(8):36−43. doi: 10.19804/j.issn1006-2513.2021.08.006
    [31]
    丁霄霄, 李凤伟, 商曰玲, 等. 灵芝多糖的复合酶法提取工艺优化[J]. 食品研究与开发,2020,41(5):34−39. [DING X X, LI F W, SHANG Y L, et al. Optimization of extraction technology of Ganoderma lucidum polysaccharide by enzyme complex[J]. Food Research and Development,2020,41(5):34−39. doi: 10.12161/j.issn.1005-6521.2020.05.006
    [32]
    CHAI Y, KAN L, ZHAO M. Enzymatic extraction optimization, anti-HBV and antioxidant activities of polysaccharides from Viscum coloratum (Kom. ) Nakai[J]. International Journal of Biological Macromolecules,2019,134:588−594. doi: 10.1016/j.ijbiomac.2019.04.173
    [33]
    CHEN Z, ZHANG W, TANG X, et al. Extraction and characterization of polysaccharides from semen cassiae by microwave-assisted aqueous two-phase extraction coupled with spectroscopy and HPLC[J]. Carbohydrate Polymers,2016:263−270.
    [34]
    ZHANG X, TENG G, ZHANG J. Ethanol/salt aqueous two-phase system based ultrasonically assisted extraction of polysaccharides from Lilium davidiivar. unicolor salisb: Physicochemical characterization and antiglycation properties[J]. Journal of Molecular Liquids,2018,256:497−506. doi: 10.1016/j.molliq.2018.02.059
    [35]
    HUANG Y, WU X, ZHOU S, et al. Biphasic extraction of different polysaccharides from radix sophorae tonkinensis by microwave-assisted aqueous two-phase extraction: Process optimization, structural characterization and mechanism exploration[J]. Separation & Purification Technology,2018,207:187−198.
    [36]
    李化, 柯华香, 李发洁, 等. Box-Behnken响应面法优选五味子多糖双水相提取工艺[J]. 中药材,2016,39(3):593−597. [LI H, KE H X, LI F J, et al. Optimization of aqueous two-phase extraction of polysaccharide from Schisandra chinensis using response surface methodology with Box-Behnken design[J]. Journal of Chinese Medicinal Materials,2016,39(3):593−597. doi: 10.13863/j.issn1001-4454.2016.03.032
    [37]
    祁小妮, 王斌, 李振亮, 等. 乙醇/(NH4)2SO4双水相体系提取红景天多糖及抑菌抗氧化活性研究[J]. 食品与发酵工业,2018,44(2):135−142. [QI X N, WANG B, LI Z L, et al. Study on the extraction of polysaccharide from rhodiola roseame by ethanol/ammonium sulphate aqueous two-phase system and its antibacterial and antioxidant activity[J]. Food and Fermentation Industries,2018,44(2):135−142.
    [38]
    党金宁, 祁小妮, 李振亮, 等. 乙醇/(NH4)2SO4双水相体系提取蕨麻多糖及其抑菌抗氧化活性[J]. 食品工业科技,2018,39(5):191−196,202. [DANG J N, QI X N, LI Z L, et al. Extraction of polysaccharide by ethanol/ammonium sulphate aqueous two-phase system from theArgentina anserina and its antibacterial and antioxidant activity[J]. Science and Technology of Food Industry,2018,39(5):191−196,202.
    [39]
    邢健敏, 李芬芳, 梁逸曾, 等. 聚乙二醇/硫酸铵双水相体系提取分离芦荟多糖及含量的测定[J]. 中国药学杂志,2007,42(7):541−544. [XING J M, LI F F, LIANG Y Z, et al. Determination and extraction of aloe polysaccharides by polyethylene glycol/(NH4)2SO4 two phase system[J]. Chinese Pharmaceutical Journal,2007,42(7):541−544. doi: 10.3321/j.issn:1001-2494.2007.07.018
    [40]
    尹明松, 丁贺辉, 潘飞兵, 等. 响应面优化超声辅助双水相提取槟榔多糖及抗氧化活性研究[J]. 食品研究与开发,2021,42(19):163−170. [YIN M S, DING H H, PAN F B, et al. Optimization of ultrasonic-assisted aqueous two-phase extraction of Areca catechu L. polysaccharide using response surface design and assessment of its antioxidant activities[J]. Food Research and Development,2021,42(19):163−170. doi: 10.12161/j.issn.1005-6521.2021.19.023
    [41]
    巫永华, 陆文静, 刘梦虎, 等. 响应面优化超声波辅助双水相提取牛蒡多糖及抗氧化分析[J]. 食品与发酵工业,2020,46(5):215−223. [WU Y H, LU W J, LIU M H, et al. Optimization of ultrasonic-assisted aqueous two-phase extraction of burdock polysaccharide by response surface design and its antioxidant activities[J]. Food and Fermentation Industries,2020,46(5):215−223. doi: 10.13995/j.cnki.11-1802/ts.022554
    [42]
    JI X, QIANG P, YUAN Y, et al. Extraction and physicochemical properties of polysaccharides from Ziziphus jujuba cv. Muzao by ultrasound-assisted aqueous two-phase extraction[J]. International Journal of Biological Macromolecules,2018,108:541−549. doi: 10.1016/j.ijbiomac.2017.12.042
    [43]
    TANG W, PENG Q X, YAN Y M, et al. Study on purification of polysaccharides in root of Salvia miltiorrhiza by macroporous adsorption resin and ion-exchange resin methods[J]. Journal of Chinese Medicinal Materials,2010,33(12):1937−1941.
    [44]
    HU Z, ZHOU H, LI Y, et al. Optimized purification process of polysaccharides from Carex meyeriana Kunth by macroporous resin, its characterization and immunomodulatory activity[J]. International Journal of Biological Macromolecules,2019,132:76−86. doi: 10.1016/j.ijbiomac.2019.03.207
    [45]
    YANG P, ZHOU M, ZHOU C, et al. Separation and purification of both tea seed polysaccharide and saponin from camellia cake extract using macroporous resin[J]. Journal of Separation Science,2015,38(4):656−662. doi: 10.1002/jssc.201401123
    [46]
    潘峰, 阮国永, 杨建波, 等. 大孔吸附树脂纯化吴茱萸果实多糖工艺优化[J]. 现代食品科技,2021,37(9):216−225. [PAN F, RUAN G Y, YANG J B, et al. Optimization of the purification process for the polysaccharides from Tetradium ruticarpum fruit using macroporous adsorption resins[J]. Modern Food Science and Technology,2021,37(9):216−225. doi: 10.13982/j.mfst.1673-9078.2021.9.0047
    [47]
    孙延芳, 梁宗锁, 张欣, 等. 芒果多糖的纯化与光谱分析[J]. 食品科学,2012,33(7):93−95. [SUN Y F, LIANG Z S, ZHANG X, et al. Purification and spectroscopic analysis of polysacchaxide from mango[J]. Food Science,2012,33(7):93−95.
    [48]
    张志宏, 邢娜, 彭东辉, 等. 黄瓜子多糖的分离、纯化和体外抗氧化活性研究[J]. 中国药房,2021,32(4):432−438. [ZHANG Z H, XING N, PENG D H, et al. Study on isolation, purification and in vitro antioxidant activity of the polysaccharides from Cucumis satiuus[J]. China Pharmacy,2021,32(4):432−438. doi: 10.6039/j.issn.1001-0408.2021.04.08
    [49]
    刘鑫, 陈香玉, 郭锐, 等. 碧螺春多糖的超声辅助酶提取工艺优化、分离纯化及性质分析[J]. 食品工业科技,2021,42(16):138−146. [LIU X, CHEN X Y, GUO R, et al. Process optimization of ultrasound-assisted enzyme extraction of biluochun polysaccharide and its separation, purification and property analysis[J]. Science and Technology of Food Industry,2021,42(16):138−146. doi: 10.13386/j.issn1002-0306.2020110007
    [50]
    龚雯, 唐婕, 韦雅渊, 等. 金花茶多糖分离纯化、结构表征及其体外抗氧化性[J]. 食品与机械,2021,37(6):184−190. [GONG W, TANG J, WEI Y Y, et al. Isolation, purification, structural characterization of polysaccharide fromCamellia nitidissima Chi and its antioxidant activities in vitro[J]. Food & Machinery,2021,37(6):184−190. doi: 10.13652/j.issn.1003-5788.2021.06.031
    [51]
    肖健, 曹荣安, 贾建, 等. DEAE琼脂糖凝胶纯化龙胆多糖及其分子特性[J]. 食品科学,2016,37(15):130−135. [XIAO J, CAO R A, JIA J, et al. Purification and molecular characterization of polysaccharides from gentianae radix et rhizoma by DEAE sepharose fast flow chromatography[J]. Food Science,2016,37(15):130−135. doi: 10.7506/spkx1002-6630-201615022
    [52]
    罗晶洁, 王尉, 曹学丽. 桑叶多糖的分离纯化及对α-葡萄糖苷酶的抑制活性[J]. 食品科学,2011,32(3):112−116. [LUO J J, WANG W, CAO X L. Isolation, purification and anti-α-glucosidase activity of polysaccharides from mulberry leaves[J]. Food Science,2011,32(3):112−116.
    [53]
    申明月, 聂少平, 谢明勇. 茶叶多糖的纯化及其光谱特性研究[J]. 食品科学,2007,28(11):39−43. [SHEN M Y, NIE S P, XIE M Y. Study on purification and characteristics of tea polysaccharide[J]. Food Science,2007,28(11):39−43. doi: 10.3321/j.issn:1002-6630.2007.11.003
    [54]
    REN Y, LIU S. Effects of separation and purification on structural characteristics of polysaccharide from quinoa (Chenopodium quinoa Willd)[J]. Biochemical and Biophysical Research Communications,2020,522(2):286−291. doi: 10.1016/j.bbrc.2019.10.030
    [55]
    李德灵, 林锦铭, 陈海平, 等. 连续动态逆流提取对香菇多糖抗氧化活性的影响[J]. 包装与食品机械,2021,39(3):35−40. [LI D L, LIN J M, CHEN H P, et al. Effect of continuous dynamic countercurrent extraction on antioxidant activity ofLentinus edodes polysaccharide[J]. Packaging and Food Machinery| Pack Food Mach,2021,39(3):35−40. doi: 10.3969/j.issn.1005-1295.2021.03.006
    [56]
    许海燕, 彭修娟, 王珊, 等. 桦菌芝多糖抗氧化性及抑菌活性研究[J]. 食品与机械,2020,36(7):171−174. [XU H Y, PENG X J, WANG S, et al. Study on antioxidant and antibacterial activities of polysaccharides in phropolyporus fomentarius[J]. Food & Machinery,2020,36(7):171−174. doi: 10.13652/j.issn.1003-5788.2020.07.035
    [57]
    CAO M, WANG S, GAO Y, et al. Study on physicochemical properties and antioxidant activity of polysaccharides from Desmodesmus armatus[J]. Journal of Food Biochemistry,2020,44(7):1−13.
    [58]
    ZHANG Y, CHEN Z, HUANG Z, et al. A comparative study on the structures of Grifola frondosa polysaccharides obtained by different decolourization methods and their in vitro antioxidant activities[J]. Food & Function,2019,10(10):6720−6731.
    [59]
    CHEN S, HUANG H, HUANG G. Extraction, derivatization and antioxidant activity of cucumber polysaccharide[J]. International Journal of Biological Macromolecules,2019,140:1047−1053. doi: 10.1016/j.ijbiomac.2019.08.203
    [60]
    刘平平, 虞旦, 王昌涛, 等. 三七发酵液多糖抗衰老活性研究[J]. 日用化学工业,2019,49(6):369−376. [LIU P P, YU D, WANG C T, et al. Study on anti-aging activity of polysaccharides in Sanqi fermentation liquor[J]. China Surfactant Detergent & Cosmetics,2019,49(6):369−376. doi: 10.3969/j.issn.1001-1803.2019.06.004
    [61]
    张诗山, 张虹, 牛锡珍, 等. 南非紫菜多糖抗衰老作用的研究[J]. 海洋科学,2013(9):68−71. [ZHANG S S, ZHANG H, NIU X Z, et al. Anti-ageing effect of polysaccharide from Porphyra capensis on ageing mice[J]. Marine Sciences,2013(9):68−71.
    [62]
    DING Q, YANG D, ZHANG W, et al. Antioxidant and anti-aging activities of the polysaccharide TLH-3 from Tricholoma lobayense[J]. International Journal of Biological Macromolecules,2016,85:133−140. doi: 10.1016/j.ijbiomac.2015.12.058
    [63]
    LI S, LIU M, ZHANG C, et al. Purification, in vitro antioxidant and in vivo anti-aging activities of soluble polysaccharides by enzyme-assisted extraction from Agaricus bisporus[J]. International Journal of Biological Macromolecules,2018,109(109):457−466.
    [64]
    WANG X, HUO X, LIU Z, et al. Investigations on the anti-aging activity of polysaccharides from Chinese yam and their regulation on klotho gene expression in mice[J]. Journal of Molecular Structure,2020,1208:127895. doi: 10.1016/j.molstruc.2020.127895
    [65]
    谢飞, 李伟, 陈美珍, 等. 野生蝉花多糖抗肿瘤活性及其作用机制[J]. 食品科学,2016,37(13):209−213. [XIE F, LI W, CHEN M Z, et al. Antitumor activity and mechanism of action of wild Cordyceps sobolifera polysaccharide[J]. Food Science,2016,37(13):209−213. doi: 10.7506/spkx1002-6630-201613038
    [66]
    钟闰, 吴思伟, 何秀苗, 等. 杜氏盐藻胞外多糖抗肿瘤活性及其机制研究[J]. 食品工业科技,2020,41(22):126−133. [ZHONG R, WU S W, HE X M, et al. Antitumor activity and mechanism of exopolysaccharide from Dunaliella salina[J]. Science and Technology of Food Industry,2020,41(22):126−133.
    [67]
    CORSO C R, OLIVEIRA N M T DE, CORDEIRO L M, et al. Polysaccharides with antitumor effect in breast cancer: A systematic review of non-clinical studies[J]. Nutrients,2021,13(6):2008. doi: 10.3390/nu13062008
    [68]
    DENG X, LI X, LUO S, et al. Antitumor activity of Lycium barbarum polysaccharides with different molecular weights: Anin vitro and in vivo study[J]. Food & Nutrition Research,2017,61(1):1399770−1399770.
    [69]
    FENG H, TIAN L. Study on extraction process of root of Henry wood betony polysaccharides and their antitumor activity against S180[J]. Molecules,2021,26(8):2359. doi: 10.3390/molecules26082359
    [70]
    刘丹奇, 任发政, 侯彩云. 几种植物多糖降血糖活性的对比研究[J]. 中国食品学报,2021,21(1):81−89. [LIU D Q, REN F Z, HOU C Y. Comparative studies on the hypoglycemic activity of several plant polysaccharides[J]. Journal of Chinese Institute of Food Science and Technology,2021,21(1):81−89.
    [71]
    吴亚楠, 邹辉, 刘玉茜, 等. 蒲公英根不同多糖组分的降血糖作用及调控途径研究[J]. 食品与发酵工业,2021,47(15):90−97. [WU Y N, ZOU H, LIU Y Q, et al. Hypoglycemic effect and regulatory pathway of different polysaccharide components from dandelion root[J]. Food and Fermentation Industries,2021,47(15):90−97. doi: 10.13995/j.cnki.11-1802/ts.026115
    [72]
    LI Q, LI W, GAO Q, et al. Hypoglycemic effect of Chinese yam (Dioscorea opposita rhizoma) polysaccharide in different structure and molecular weight[J]. Journal of Food Science,2017,82(10):2487−2494. doi: 10.1111/1750-3841.13919
    [73]
    LIU W, LV X, HUANG W, et al. Characterization and hypoglycemic effect of a neutral polysaccharide extracted from the residue of Codonopsis pilosula[J]. Carbohydrate Polymers,2018,197:215−226. doi: 10.1016/j.carbpol.2018.05.067
    [74]
    WU H, MA Z, ZHANG D, et al. Sequential extraction, characterization, and analysis of pumpkin polysaccharides for their hypoglycemic activities and effects on gut microbiota in mice[J]. Frontiers in Nutrition,2021,8:769181. doi: 10.3389/fnut.2021.769181
    [75]
    张廷婷, 赵文颖, 谢倍珍, 等. 黑木耳及其多糖对高脂饮食大鼠的降血脂和肠道菌群调节作用[J]. 中国食品学报,2021,21(9):89−101. [ZHANG T T, ZHAO W Y, XIE B Z, et al. Effects of auricularia auricula and its polysaccharides on hypolipidemic and regulating intestinal flora in high-fat diet rats[J]. Journal of Chinese Institute of Food Science and Technology,2021,21(9):89−101. doi: 10.16429/j.1009-7848.2021.09.010
    [76]
    杨明琛, 袁梦欣, 陆维, 等. 黄精多糖体外消化特性及对Ⅱ型糖尿病小鼠肠道菌群的调节作用[J]. 现代食品科技,2021,37(8):14−21. [YANG M C, YUAN M X, LU W, et al. In vitro digestion properties of Polygonatum sibiricum polysaccharide and its regulatory action on the gut microbiota in T2DM mice[J]. Modern Food Science & Technology,2021,37(8):14−21. doi: 10.13982/j.mfst.1673-9078.2021.8.1181
    [77]
    李珊, 孙万成, 罗毅皓. 非淀粉多糖对肠道菌群的调节作用及其对代谢疾病影响的研究概述[J]. 食品研究与开发,2021,42(19):219−224. [LI S, SUN W C, LUO Y H. Regulatory effects of non-starch polysaccharides and intestinal microbiota and their effects on metabolic diseases[J]. Food Research and Development,2021,42(19):219−224. doi: 10.12161/j.issn.1005-6521.2021.19.031
    [78]
    FU Y, FENG B, ZHU Z, et al. The Polysaccharides from Codonopsis pilosula modulates the immunity and intestinal microbiota of cyclophosphamide-treated immunosuppressed mice[J]. Molecules,2018,23(7):1801. doi: 10.3390/molecules23071801
    [79]
    WANG Y, SUN M, JIN H, et al. Effects of lycium barbarum polysaccharides on immunity and the gut microbiota in cyclophosphamide-induced immunosuppressed mice[J]. Frontiers in Microbiology,2021,12:701566. doi: 10.3389/fmicb.2021.701566
    [80]
    GE Y, AHMED S, YAO W, et al. Regulation effects of indigestible dietary polysaccharides on intestinal microflora: An overview[J]. Journal of Food Biochemistry,2021,45(1):45−52.
    [81]
    吴磊, 吴静, 胡居吾, 等. 白莲莲子皮多糖的理化性质及免疫调节活性[J]. 现代食品科技,2021,37(5):100−108,129. [WU L, WU J, HU J W, et al. Physicochemical properties and immunomodulatory activities of polysaccharides from white lotus seed skin[J]. Modern Food Science & Technology,2021,37(5):100−108,129. doi: 10.13982/j.mfst.1673-9078.2021.5.1008
    [82]
    郝敏, 李殿龙, 徐俊亭, 等. 黑木耳胞外多糖对小鼠肠道微生态及免疫调节的影响[J]. 中国食品学报,2021,21(3):63−70. [HAO M, LI D L, XU J T, et al. Effects of exopolysaccharides from auricularia auricula-judae on the intestine microecology and immunomodulatory in mice[J]. Journal of Chinese Institute of Food Science and Technology,2021,21(3):63−70. doi: 10.16429/j.1009-7848.2021.03.007
    [83]
    谌淑平, 李明智, 董楠, 等. 不同食用菌多糖复配物对RAW264.7巨噬细胞的免疫调节作用[J]. 食品工业科技,2021,42(17):366−372. [CHEN S P, LI M Z, DONG N, et al. Immunomodulatory effects of different edible fungi polysaccharide complex on RAW264.7 macrophages[J]. Science and Technology of Food Industry,2021,42(17):366−372. doi: 10.13386/j.issn1002-0306.2020110143
    [84]
    WANG Y, ZHANG Y, SHAO J, et al. Study on the immunomodulatory activity of a novel polysaccharide from the lichen Umbilicaria Esculenta[J]. International Journal of Biological Macromolecules,2019,121:846−851. doi: 10.1016/j.ijbiomac.2018.10.080
    [85]
    FAN W, ZHANG S, HAO P, et al. Structure characterization of three polysaccharides and a comparative study of their immunomodulatory activities on chicken macrophage[J]. Carbohydrate Polymers,2016,153:631−640. doi: 10.1016/j.carbpol.2016.07.116
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