Optimization of Ultrasound-Assisted Extraction of Cyclic Adenosine 3',5'-Monophosphate from Xinjiang Jujube by Deep Eutectic Solvent

ZHANG Xue; LIU Ya; LIU Xiumin; SHAN Chunhui

doi:10.13386/j.issn1002-0306.2021100308

Volume 43 Issue 14

Jul. 2022

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Science and Technology of Food Industry > 2022 > 43(14): 243-250. > DOI: 10.13386/j.issn1002-0306.2021100308

ZHANG Xue, LIU Ya, LIU Xiumin, et al. Optimization of Ultrasound-Assisted Extraction of Cyclic Adenosine 3',5'-Monophosphate from Xinjiang Jujube by Deep Eutectic Solvent[J]. Science and Technology of Food Industry, 2022, 43(14): 243−250. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2021100308.

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Optimization of Ultrasound-Assisted Extraction of Cyclic Adenosine 3',5'-Monophosphate from Xinjiang Jujube by Deep Eutectic Solvent

ZHANG Xue^1,,
LIU Ya¹,
LIU Xiumin¹,
SHAN Chunhui^{1, 2, ,}

1.
College of Food Science, Shihezi University, Shihezi 832000, China
2.
Engineering Research Center of Xinjiang Ministry of Education for Fruit and Vegetable Storage and Processing, Shihezi 832000, China

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Received Date: October 31, 2021
Available Online: May 17, 2022

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Abstract

Abstract

Using green and highly efficient deep eutectic solvent (DES) as the extraction agent, this study extracted the functional ingredient—cyclic adenosine 3',5'-monophosphate (cAMP) from Xinjiang jujube through ultrasound-assisted technology. The relationships between the molar ratio of deep eutectic solvent, water content of deep eutectic solvent, solid-liquid ratio, ultrasonic time, ultrasonic temperature and extraction amount of cAMP were studied. Through single factor experimentas and response surface optimization experiment, the optimal conditions for cAMP extraction from Xinjiang jujube were as follows: The molar ratio of choline chloride to glycerol was 1:3, the water content of DES system was 44%, the solid-liquid ratio of jujube powder to DES was 1:35 g/mL, the ultrasonic time was 45 min, and the ultrasonic temperature was 45 ℃. At this time, compared with water extraction and alcohol extraction under the same ultrasonic conditions, the highest content of cAMP extracted by deep eutectic solvent was (284.15±0.06) μg/g. Therefore, ultrasonic-assisted deep eutectic solvent extraction of cAMP in Xinjiang jujube was a new, efficient and safe method to obtain a higher extraction amount.
- Xinjiang jujube,
- cyclic adenosine monophosphate,
- deep eutectic solvent,
- ultrasonic assisted,
- high performance liquid chromatography

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References (34)

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