Determination of 23 Low-molecular-weight Organic Components Content in Infant Formulas by Quantitative Nuclear Magnetic Resonance with Global Spectral Deconvolution

LI Wei; WANG Yihan; JIANG Jie; LIN Li

doi:10.13386/j.issn1002-0306.2020050061

Volume 42 Issue 3

Jan. 2021

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Science and Technology of Food Industry > 2021 > 42(3): 241-246. > DOI: 10.13386/j.issn1002-0306.2020050061

LI Wei, WANG Yihan, JIANG Jie, LIN Li. Determination of 23 Low-molecular-weight Organic Components Content in Infant Formulas by Quantitative Nuclear Magnetic Resonance with Global Spectral Deconvolution[J]. Science and Technology of Food Industry, 2021, 42(3): 241-246. DOI: 10.13386/j.issn1002-0306.2020050061

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Determination of 23 Low-molecular-weight Organic Components Content in Infant Formulas by Quantitative Nuclear Magnetic Resonance with Global Spectral Deconvolution

Beijing Municipal Center for Food Safety Monitoring and Risk Assessment, Beijing 100094, China

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Received Date: May 07, 2020
Available Online: February 02, 2021

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Abstract

Abstract

To establish the quantification method for 23 low-molecular-weight organic components(nucleotides,nucleosides,organic acids and amino acids)in infant formulas,quantitative nuclear magnetic resonance(qNMR)technique was employed based on processing approach of global spectral deconvolution(GSD).The results revealed that it showed a good linear correlation for 23 components in the given concentration ranges(R²=0.9960~0.9997),with the RSD of precision between 1.02%~3.72%,the RSD of repeatability between 1.34%~3.68%,the RSD of stability between 1.62%~3.20%,and the recovery rate between 85.02%~110.00%.The choline content determined by this method was compared with the national standard method,and the results were consistent(RSD<15%).The results indicated that GSD-qNMR method was better than the traditional qNMR method,and was more suitable for the quantitative detection of low-molecular-weight organic components in complex food matrix such as infant formula.
- quantitative nuclear magnetic resonance(qNMR),
- global spectral deconvolution,
- infant formulas,
- quantitation

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