Supercritical fluid extraction of total flavonoids from Zanthoxylum bungeagum maxim pericarp

The total flavonoids from Zanthoxylum bungeagum maxim pericarp was extracted by supercritical fluid extraction (SFE) , and the total flavonoid content in the extract was investigated by the sodium nitrite-aluminum nitrate method with Rutin as a standard product. The effects of pressure, temperature, dosage of chemical preparation and time on extract abilities of flavone were investigated. The optimum technology parameter was investigated by the orthogonal design:the factors influencing the yield were as follows:temperature>pressure>time>dosage of chemical preparation, as a result, the best craft conditions were extraction temperature 50℃, extraction pressure 35MPa, extraction time 150min, dosage of chemical preparation 4mL/g, and the extraction rate was 19.574%.