Optimization of Ultrasonic-Assisted Extraction of Phenolic Compounds from Eggplant Peel and Its Hypoglycemic Effect

GUAN Yuting; CHEN Ruirui; CAI Ruyu; FAN Bei; SUN Jing; ZHANG Rui; ZHANG Ziyang; CHANG Shimin

doi:10.13386/j.issn1002-0306.2022030322

Volume 43 Issue 24

Dec. 2022

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Science and Technology of Food Industry > 2022 > 43(24): 254-260. > DOI: 10.13386/j.issn1002-0306.2022030322

GUAN Yuting, CHEN Ruirui, CAI Ruyu, et al. Optimization of Ultrasonic-Assisted Extraction of Phenolic Compounds from Eggplant Peel and Its Hypoglycemic Effect[J]. Science and Technology of Food Industry, 2022, 43(24): 254−260. (in Chinese with English abstract). doi: 10.13386/j.issn1002-0306.2022030322.

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Optimization of Ultrasonic-Assisted Extraction of Phenolic Compounds from Eggplant Peel and Its Hypoglycemic Effect

GUAN Yuting^{1, 2,},
CHEN Ruirui^{1, 2,},
CAI Ruyu^{1, 2},
FAN Bei³,
SUN Jing³,
ZHANG Rui^{1, 2},
ZHANG Ziyang^{1, 2},
CHANG Shimin^{1, 2, ,}

1.
College of Life Sciences and Food Engineering, Hebei University of Engineering, Handan 056038, China
2.
Handan Key Laboratory of Natural Products and Functional Foods, Handan 056038, China
3.
Institute of Food Science and Technology CAAS, Beijing 100193, China

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Received Date: March 27, 2022
Available Online: October 11, 2022

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Abstract

Abstract

Objective: In order to improve the added value of eggplant peel, the best method of phenolic compounds from eggplant peel (EPP), as well as its hypoglycemic impact in vitro and in vivo were studied. Methods: EPP was extracted by ultrasonic-assisted method. The extraction parameters of EPP were optimized by single factor experiments and orthogonal experiment with yield as evaluation index. The inhibitory rate of EPP on α-glucosidase and its effects on body weight, fasting glucose, and glucose tolerance in mice were analyzed to evaluate its hypoglycemic efficacy in vitro and in vivo. Results: The optimal extraction conditions were as follows: Ultrasonic power 540 W, solid-liquid ratio 1:50 g/mL, extraction temperature 50 ℃ and extraction time 50 min. The extraction yield of EPP was 43.21%. The inhibitory rate on α-glucosidase increased with the increase of EPP concentration, and the inhibition rate of α-glucosidase was 45.46% with 1 mg/mL EPP. The body weight, fasting blood glucose and glucose tolerance of diabetic mice could be improved by EPP, and it had a significant hypoglycemic effect on diabetic mice. Conclusion: This study confirmed that EPP had hypoglycemic effect, which laid a theoretical foundation for comprehensive development and utilization of eggplant peel.
- eggplant peel,
- phenolic compounds,
- ultrasound-assisted,
- α-glucosidase,
- hypoglycemic,
- glucose tolerance

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Optimization of Ultrasonic-Assisted Extraction of Phenolic Compounds from Eggplant Peel and Its Hypoglycemic Effect

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