基于色谱-质谱法分析食品中硝基咪唑类药物残留的研究进展

基金项目:

国家重点研发计划(2018YFC1602300)

烟台市重点研发计划(2018ZDCX014)

山东省高等学校食品安全与营养健康创新团队发展计划

山东省重点研发计划(2019GSF108014)

莱阳市新旧动能转换科技创新计划。

泰山产业领军人才工程(LJNY201705)

详细信息

Advances in the Analysis of Nitroimidazoles Residues in Food by Chromatography-Mass Spectrometry

1. Key Laboratory of Food Processing Technology and Quality Control in Shandong Province, College of Food Science and Engineering, Shandong Agriculture University, Taian 271018, China;
2. Beijing Centre for Physical&Chemical Analysis, Beijing Key Laboratory of Organic Materials Testing Technology&Quality Evaluation, Beijing 100089, China;
3. Shandong Analysis and Test Center, Qilu University of Technology(Shandong Academy of Sciences), Jinan 250014, China

摘要: 硝基咪唑类药物是一类具有抗菌、抗原虫作用的化合物,广泛用于兽禽饲料。硝基咪唑类物质及其代谢物的复杂性导致该类组分的检测困难且方法复杂繁琐。本文论述了硝基咪唑类兽药分析检测的研究背景和现状,并对国内外肉类食品中硝基咪唑类兽药残留的前处理方法及其检测方法进行综述,同时对硝基咪唑类药物及其代谢产物残留分析的研究方向进行了展望。
- 兽药残留 /
- 硝基咪唑类 /
- 前处理 /
- 检测方法
Abstract: Nitroimidazole drugs are a kind of antibacterial and antigenic compounds, which are widely used in animal feed. The complexity of nitroimidazole and its metabolites make it difficult to detect these components and the method is complex and tedious. In this paper, the research background and present situation of nitroimidazole veterinary drug analysis and detection are discussed, and the pretreatment methods and detection methods of nitroimidazole veterinary drug residues in meat food at home and abroad are reviewed. At the same time, the research direction of nitroimidazole drugs and their metabolites residue analysis is prospected.
- veterinary drug residues /
- nitroimidazoles /
- pre-processing /
- detection method