Abstract: Mulberry leaves (MLs) have been used traditionally to raise silkworms and as herbs and herbal drinks . This article summarizes the pharmacological effects of mulberry leaves on the human body such as lowering blood sugar, lowering blood pressure, preventing cancer and urinating. The application of mulberry leaves in food and animal production are summarized, and the current problems in mulberry leaves research are carried out. The analysis and prospects for the further comprehensive utilization of mulberry leaves are aimed at providing theoretical references for mulberry leaf deep-processing technology innovation, high-efficiency comprehensive utilization of resources, and common key technology innovation and product development for high-value processing of resources.