Abstract: As a dual-purpose resource of medicine and food, Moringa oleifera leaves are rich in protein, polysaccharide, vitamins, minerals and other nutrients, as well as flavonoids, polyphenols and other active chemical components, which has become a research hotspot in food, feed and medicine industries in recent years. Moringa oleifera leaves have many physiological functions, such as hypoglycemic, antioxidant, anticancer, antibacterial and so on. However, the health food with Moringa oleifera leaves as the effective component are still in the research stage, and its medicinal value needs to be further explored. In this paper, the nutritional composition, physiological activity, function and practical application of Moringa oleifera leaves are reviewed, and the future development in food, medicine and other fields is prospected, in order to provide theoretical basis for more scientific understanding and in-depth study of Moringa oleifera leaves, and provide effective reference for comprehensive utilization of Moringa oleifera leaves.