鲟鱼皮二肽基肽酶-IV抑制肽咀嚼片的制备工艺优化

尹剑; 徐睿; 阿热爱·巴合提; 李平兰; 武瑞赟

doi:10.13386/j.issn1002-0306.2020030426

鲟鱼皮二肽基肽酶-IV抑制肽咀嚼片的制备工艺优化

1. 中国农业大学食品科学与营养工程学院, 北京 100083;
2. 北京水产技术推广站, 北京 100176;
3. 新疆维吾尔自治区产品质量监督检验研究院, 新疆乌鲁木齐 830013

基金项目:

北京市鲟鱼鲑鳟鱼创新团队项目（BAIC08-2020）。

详细信息

作者简介:
尹剑(1994-),男,硕士,研究方向:功能性食品,E-mail:yinjian398144775@163.com。

通讯作者:
武瑞赟(1990-),女,博士,研究方向:食品微生物,E-mail:wuruiyun814@163.com。

中图分类号: TS254.9
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- 文章访问数: 330
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出版历程
- 收稿日期: 2020-03-31
- 网络出版日期: 2021-01-20
- 刊出日期: 2021-01-14

Optimization of Preparation Technology of Sturgeon Skin Dipeptidyl Peptidase-IV Inhibitory Peptide Chewable Tablets

1. College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China;
2. Beijing Aquatic Technology Promotion Station, Beijing 100176, China;
3. Xinjiang Uygur Autonomous Region Product Quality Supervision and Inspection Institute, Urumqi 830013, China

摘要

摘要: 针对市场上含有鲟鱼皮二肽基肽酶-IV （Dipeptidyl peptidase IV，DPP-IV）抑制肽咀嚼片的相关产品较少的问题，采用湿法造粒技术和模糊数学法分析方法及单因素实验、响应面试验及正交试验，对咀嚼片配方及制备工艺进行优化。结果表明：咀嚼片最优配方为肽粉添加量46.52%，木糖醇添加量23.94%，CMC-Na添加量7.88%，硬脂酸镁添加量7.00%，奶粉及微晶纤维素添加量分别为10%与4.66%；在转台速度20 r/min，充填深度11 mm，充填压力28 kN，原料粒度350目的制备条件下，制得的咀嚼片硬度适中，表面光滑且色泽均匀，模糊数学分析法综合得分为69.75分。本研究通过辅助加料配合湿法造粒技术，对鲟鱼皮DPP-IV抑制肽咀嚼片的配方及制备工艺进行优化，旨在为咀嚼片产品的制备提供理论支持。
- 鲟鱼皮 /
- 二肽基肽酶-IV(DPP-IV)抑制肽咀嚼片 /
- 湿法制粒
Abstract: In order to solve the problem that there are few DPP-IV products in the market,the wet granulation technology,fuzzy mathematics analysis method,single factor test,response surface test and orthogonal test were used to optimize the formulation and preparation process of chewable tablets. The results showed that,the optimal formula of chewable tablet were 46.52% peptide powder,23.94% xylitol,7.88% CMC-Na,7.00% magnesium stearate,10% and 4.66% residual milk powder and microcrystalline cellulose. The speed was 20 r/min,the filling depth was 11 mm,and the filling pressure was 28 kN,under the condition of 350 mesh size of raw material,the chewable tablets had moderate hardness,smooth surface and uniform color,and the comprehensive score of fuzzy mathematical analysis was 69.75 scores. In this study,the formulation and preparation process of DPP-IV inhibitory peptide chewable tablets for sturgeon skin were optimized by auxiliary feeding and wet granulation technology to provide theoretical support for the preparation of chewable tablets.
- sturgeon skin /
- dipeptidyl peptidase IV(DPP-IV)inhibitory peptide chewable tablets /
- wet granulation

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