Abstract: A method for determination of 11 kinds of pesticide residues in apple and tomato by gas chromatography-mass spectrometry was established in this study. The sample was extracted by acetonitrile,purified through SPE NH₂ column,and then the purified solution wad concentrated,redissolved with n-hexane,and determined by gas chromatography-mass spectrometry,and quantified by external standard method. The results showed that within a certain mass concentration range,the correlation coefficients of the linear equation of 11 kinds of pesticides in the two substrates were more than 0.998,the detection limit and the quantitative limit were respectively 0.0038~0.0300 and 0.0126~0.1000 mg/kg,and the average recoveries of 6 parallel samples addition standards at 3 concentration points were between 81.4% and 118.3%,and the relative standard deviation was less than 10%. This method had the advantages of simple and rapid pretreatment,high accuracy and precision,and low detection cost relatively.