Abstract: Aluminum and titanium in sweet potato vermicelli were detected by ICP-MS (Inductively Coupled Plasma Mass Spectrometry). After microwave digestion, the sample was used in the determination of aluminum and titanium, in the condition of ⁴⁵Sc as the internal standard. The linear ranges of Al and Ti were 0~80 ng·mL^-1 (R²=0.9993), 0~50 ng·mL^-1 (R²=1.0000). The recoveries rate of aluminum and titanium were 82.2%~95.5% and 86.3%~93.2% respectively, with the relative standard deviations 0.7%~1.7% and 0.3%~1.3%. The limit of detection (LOD) and the limit of quantization (LOQ) about Al were 0.01 mg/kg and 0.03 mg/kg, respectively. The LOD and LOQ of Ti were 0.01 mg/kg and 0.02 mg/kg, respectively. In the stability experiment, the RSD of aluminum and titanium were 4.67%, 9.12% during 8 hours. In the repeatability experiments, the RSD of aluminum and titanium were 2.04%, 1.97%. This simple, high sensitivity, wide linear range and accurate method was applied to the analysis of Al and Ti elements of the sweet potato vermicelli. This could provide data reference for the scientific evaluation of Al and Ti elements contents in the sweet potato vermicelli.