Effect of consumption of seasoned flour products on gut microbiota in young volunteers
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摘要: 招募了9名在校大学生志愿者,每位志愿者每隔一天食用一包约150 g的调味面制品,持续2周累计食用7包,分别于食用前一日、食用完次日及2周后采集粪便样品,并采用高通量测序技术对其肠道微生物群落结构进行解析。通过配对t检验发现,食用调味面制品2周可以显著提高志愿者肠道微生物的多样性和丰富度(p<0.05),而对优势菌属的相对含量没有影响(p>0.05)。通过基于Uni Frac距离的主坐标分析和基于Meta-Storm距离的非参数多元方差分析发现,食用调味面制品2周不会对志愿者肠道菌群群落结构产生影响。Abstract: In the current study, 9 young volunteers were recruited and each subject consumption of a packet of seasoned flour products with the weight of 150 g for a continuous period of 2 weeks. Meanwhile, gut microbiota of subjects were monitored before starting, during and after stopping consumption for 2 weeks using high throughput sequencing technologies. The result indicated that consumption of seasoned flour products for 2 weeks significantly increased the gut microbiota diversity and richness by paired t test ( p < 0.05) , but had no influence on the relative abundance of domain bacterial genus ( p > 0.05) .Through principal coordinate analysis based on Uni Frac and PERMANOVA based on Meta-Storm, it was shown that the consumption of seasoned flour products for 2 weeks couldn't alter the structural of gut microbiota.
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Keywords:
- seasoned flour products /
- high throughput sequencing /
- gut microbiota /
- young
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